Iron Metabolism, Vol 110

  • ID: 4622075
  • Book
  • 300 Pages
  • Elsevier Science and Technology
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Iron Metabolism, Volume 110, the latest release in the Vitamins and Hormones series first published in 1943, covers the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms, with this release focusing on topics relating to hepcidin, bacterial infection, and iron overload, the role of heparan sulfates in hepcidin regulation, hepcidin CDNA and human gene sex hormones, growth factors and hepcidin, HFE gene polymorphisms and hereditary hemochromatosis, hepcidin and il-1beta, hepcidin-ferroportin axis, cardiomyocyte hepcidin, adipocyte iron, leptin and hepcidin, regulators of hepcidin expression, and much more.

  • Focuses on the newest aspects of hormone action in connection with diseases
  • Lays the groundwork for the focus of new chemotherapeutic targets
  • Represents reviews on emerging areas in hormone action, cellular regulators and signaling pathways
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Preface Gerald Litwack 1. HEPCIDIN, BACTERIAL INFECTION, AND IRON OVERLOAD Ron Acton and James Barton 2. THE ROLE OF HEPARAN SULFATES IN HEPCIDIN REGULATION Paolo Arosio 3. HEPCIDIN cDNA AND HUMAN GENE Mohamed Boumaiza 4. SEX HORMONES, GROWTH FACTORS AND HEPCIDIN Paresh Dandona 5. HFE GENE POLYMORPHISMS AND HEREDITARY HEMOCHROMATOSIS Nikolaos Drakoulis 6. HEPCIDIN & IL-1beta Funaba Masayuki 7. HEPCIDIN-FERROPORTIN AXIS Yelene Ginzburg 8. CARDIOMYOCYTE HEPCIDIN Samira Lakhal-Littleton 9. ADIPOCYTE IRON, LEPTIN AND HEPCIDIN Donald A. McClain 10. REGULATORS OF HEPCIDIN EXPRESSION Marie-Paule Roth and Helene Coppin 11. SPLICING VARIANT OF HEPCIDIN mRNA Katsunori Sasaki 12. HEPCIDIN AND THE BMP-SMAD PATHWAY Laura Silvestri, Antonella Nai and Alessia Pagani 13. Hfe/Tfr2 NULL MICE AND HEPCIDIN Nathan Subrumaniam
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Litwack, Gerald
Dr. Gerald Litwack obtained M.S. and PhD degrees from the University of Wisconsin Department of Biochemistry and remained there for a brief time as a Lecturer on Enzymes. Then he entered the Biochemical Institute of the Sorbonne as a Fellow of the National Foundation for Infantile Paralysis. He next moved to Rutgers University as an Assistant Professor of Biochemistry and later as Associate Professor of biochemistry at the University of Pennsylvania Graduate School of Medicine. After four years he moved to the Temple University School of Medicine as Professor of Biochemistry and Deputy Director of the Fels Institute for Cancer Research and Molecular Biology, soon after, becoming the Laura H. Carnell Professor. Subsequently he was appointed chair of Biochemistry and Molecular Pharmacology at the Jefferson Medical College as well as Vice Dean for Research and Deputy Director of the Jefferson Cancer Institute and Director of the Institute for Apoptosis. Following the move of his family, he became a Visiting Scholar at the Department of Biological Chemistry of the Geffen School of Medicine at UCLA and then became the Founding Chair of the Department of Basic Sciences at the Geisinger Commonwealth School of Medicine, becoming Professor of Molecular and Cellular Medicine and Associate Director of the Institute for Regenerative Medicine at the Texas A&M Health Science Center as his final position. During his career he was a visiting scientist at the University of California, San Francisco and Berkeley, Courtauld Institute of Biochemistry, London and the Wistar Institute. He was appointed Emeritus Professor and/or Chair at Rutgers University, Thomas Jefferson University and the Geisinger Commonwealth School of Medicine. He has published more than 300 scientific papers, authored three textbooks and edited more than sixty-five books. Currently he lives with his family and continues his authorship and editorial work in Los Angeles.
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