Biointegration of Medical Implant Materials, Second Edition, provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration. New sections discuss soft tissue integration, with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering, and vascular grafts. Other sections review tissue regeneration, inorganic nanoparticles for targeted drug delivery, alginate based drug delivery devices, and design considerations, with coverage of the biocompatibility of materials and their relevance to drug delivery and tissue engineering. With its distinguished editor and team of international contributors, this book is ideal for medical materials scientists and engineers in industry and academia.
- Provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration
- Discusses soft tissue biointegration, with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering, vascular grafts and replacement materials for facial reconstruction
- Includes new information on a variety of tissue regeneration techniques and applications
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1. Biointegration: an introduction
Part One Soft tissue biointegration 2. Interface biology of stem cell-driven tissue engineering: concepts, concerns, and approaches 3. Replacement materials for facial reconstruction at the soft tissue-bone interface 4. Tissue engineering for small-diameter vascular grafts 5. Clinical applications of mesenchymal stem cells
Part Two Tissue regeneration 6. Cardiac Regeneration 7. Tissue-based products 8. Tendon and tissue regeneration 9. Integration of dental implants: molecular interplay at tissue-material interface 10. Biointegration of bone graft substiutes from osteointegration to osteotranduction 11. Stem cell-based therapeutic approaches toward corneal regeneration
Part Three Drug delivery 12. Biocompatibility of materials and its relevance to drug delivery and tissue engineering 13. Inorganic nanoparticles for targeted drug delivery 14. Applications of alginate biopolymer in drug delivery
Part Four Design considerations 15. Failure mechanisms of medical implants and their effects on outcomes 16. Biointegration of three-dimensional-printed biomaterials and biomedical devices
Dr Chandra P. Sharma is the Founder of Society for Biomaterials and Artificial Organs India (SBAOI) & Society for Tissue Engineering and Regenerative Medicine India (STERMI). He is Hon. Emeritus Professor CBEAS Purbanchal University, Kathmandu, Nepal and Hon Editor in Chief Trends in Biomaterials and Artificial Organs-an international journal published by SBAOI.
He has been Senior Scientist and Head Biomedical Technology Wing (BMT Wing) Associate Head BMT Wing and Associate Dean PhD affairs Sree Chitra Thirunal Institute for Medical Science and Technology, Trivandrum, India. He has also been adjunct Professor Department of Pharmaceutical Biotechnology,Manipal University India. Dr Sharma is Fellow of the International Union of Societies for Biomaterials Science and Engineering. He has published over 400 papers including book chapters , processed 40 patents in various countries and edited/coauthored six books. He has been guest editor of several issues of international journals and presently member of the editorial board of many Journals.
Dr Sharma received his Biomaterials training with Prof DJ Lyman, University of Utah as a graduate student and with Prof David F Williams, University of Liverpool as Postdoctoral research associate.