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The Laboratory Rat. Edition No. 3. American College of Laboratory Animal Medicine

  • ID: 4759427
  • Book
  • November 2019
  • Region: United States
  • Elsevier Science and Technology

The third edition of The Laboratory Rat features updated information on a variety of topics, including rats as research models for basic and translational research in areas such as genomics, alcoholism, diabetes, metabolic syndrome, obesity, neuroscience, spinal cord injury, traumatic brain injury, regenerative medicine, and infectious disease. New information related to the husbandry and veterinary care of rats is provided including topics related to nutrition, reproduction, anesthesia and surgery, infectious and noninfectious disease, and the care of surgical and other fragile models.  It is a premier source of information on the laboratory rat, this book will be of interest to veterinary and medical students, senior graduate students, postdocs and researchers who utilize animals in biomedical research.

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Background of the laboratory rat 1. Historical Foundations 2. Taxonomy and Stocks and Strains 3. Translational Potential of Rats in Research

Biology and care 4. Functional Anatomy and Physiology 5. Clinical Pathology of the Rat 6. Reproduction and Breeding 7. Assisted Reproductive Technologies and Genetic Modification in Rats 8. Analysis of Behavior in Laboratory Rats 9. Nutrition 10. Housing and Environment

Clinical care and disease 11. Medical Management and Diagnostic Approaches 12. Bacterial, Mycoplasmal, and Mycotic Infections 13. Viral Disease 14. Parasitic Diseases 15. Neoplastic Disease 16. Metabolic, Traumatic, and Miscellaneous Diseases 17. Anesthesia, Analgesia, and Euthanasia 18. Care of Surgical and Other Fragile Models

Rats as research models 19. General Experimental Techniques 20. Integrating Biology with Rat Genomic Tools 21. Gnotobiotics and the Microbiome 22. Toxicology 23. Embryology and Teratology 24. Rat Immunology 25. Cardiovascular Research 26. Rat Models of Alcohol Use Disorder 27. Rat Models of Obesity, Metabolic Syndrome, and Diabetes 28. The Rate in Neuroscience Research 29. Rat Models of Central Nervous System Injury 30. Use of the Rat as a Model in Regenerative Medicine 31. Rat Models of Infectious Disease
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Mark A. Suckow Associate Vice President for Research, Attending Veterinarian, Professor, Biomedical Engineering, University of Kentucky, Lexington, KY..

Mark A. Suckow, DVM, DACLAM, is the Associate Vice President for Research, Attending Veterinarian, and Professor of Biomedical Engineering at the University of Kentucky. He is on the council on Accreditation at the Association for Assessment and Accreditation of Laboratory Animal Care International. Dr. Suckow has 25 years of experience with IACUC organization and regulatory compliance, laboratory animal medicine, research with a variety of animal models, and animal facility design and management. He is the previous editor of laboratory animal publications with CRC Press and AP/Elsevier, including Principles of Animal Research, Research Regulatory Compliance and The Laboratory Rabbit, Guinea Pig, Hamster and Other Rodents
F. Claire Hankenson Director, MSU Campus Animal Resources, Michigan State University, East Lansing, MI, USA.

F. Claire Hankenson, DVM, MS, is the Director of MSU Campus Animal Resources and Attending Veterinarian at the Michigan State University. Research interests are refinements in the case and use of animals involved in research studies, particularly rodent clinical medicine, tail biopsy evaluations and humane endpoints.
Ronald P. Wilson Professor and Chair, Department of Comparative Medicine, Penn State University College of Medicine, Hershey, PA, USA.

Ronald P. Wilson, VMA, MS, DACLAM, is the Professor and Chair of Comparative Medicine at Pennsylvania State University. Research interests are related to experimental surgery, pain, analgesia and anesthesia of laboratory animals.
Patricia L. Foley Director, Division of Comparative Medicine, Georgetown University, Washington, DC, USA.

Patricia L. Foley, DVM, DCLAM, is the Director, Division of Comparative Medicine at Georgetown University.
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