This issue of Neurosurgery Clinics, guest edited by Drs. Guy McKhann and Hugues Duffau, with consulting editors Russell R. Lonser and Daniel K. Resnick, will focus on Low-Grade Glioma. Topics includes, but are not limited to, Epidemiology and Molecular Epidemiology; WHO Pathological and Molecular Classification; Molecular Pathogenesis; Glioma Cell Migration and Heterogeneity; Clinical Presentation, Natural History, and Prognosis; LGG Epilepsy; MRI, fMRI, DTI, Molecular Imaging; Brain Mapping Techniques in LGG; Surgical Adjuncts to Increase EOR iMRI, Flourescence, Raman Histology; Mapping Cognition and Emotion; Extent of Resection; EOR vs Molecular Classification; Chemotherapy Treatment and Trials; Radiotherapy Treatment and Trials; Higher Order Surgical Questions; and Building a Glioma Practice.
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Table of Contents
1. Epidemiology and Molecular Epidemiology2. Molecular Pathogenesis
3. Alterations in the Brain Microenvironment in Diffusely Infiltrating Low Grade Glioma
4. Clinical Presentation, Natural History and Prognosis of Diffuse Low-Grade Gliomas
5. LGG Epilepsy
6. Mapping in Low Grade Glioma Surgery: Low and High Frequency Stimulation
7. Surgical Adjuncts to Increase EOR iMRI, Fluorescence, Raman Histology
8. Beyond Language: Mapping Cognition and Emotion
9. Evidence for Improving Outcome through Extent of Resection
10. EOR Versus Molecular Classification: What Matters When?
11. Chemotherapy Treatment and Trials in Low Grade Gliomas
12. Low-Grade Glioma Radiotherapy Treatment and Trials
13. Higher Order Surgical Questions for Diffuse Low-Grade Gliomas: Supramaximal Resection, Neuroplasticity and Screening
14. Building a Glioma Practice
