Arousal in Neurological and Psychiatric Diseases aims to focus attention on the dysregulation of arousal, which is found in many neurological and psychiatric disorders. Chapters describe the physiology of each process, how it is disturbed in each disorder, and what the most appropriate treatment(s) should be. The book also imparts the understanding of the RAS as a system not only modulating waking, but also in charge of survival mechanisms such as fight vs flight responses and reflexes. The full spectrum of these functions helps explain the complexity of symptoms evident in such disorders as disparate as schizophrenia and Parkinson's disease. The reader will develop an understanding of this homeostatic mechanism that has synergistic action with other such mechanisms as appetite.
This is the first book to discuss the function of the RAS with respect to higher functions, motor control, and the intertwining of arousal and motor disorders. This book will help neuroscientists, sleep researchers, neurologists and psychiatrists understand the basic mechanisms that modulate arousal in health and disease, and also promote the knowledge that therapies that address arousal dysregulation can alter the severity and manifestation of multiple disorders.
- Provides a comprehensive overview of the basic mechanisms behind dysregulation of arousal in neurological and psychiatric disorders
- Describes in detail the function of the Reticular Activating System with respect to higher functions, motor control, and the intertwining of arousal and motor disorders
- Cover multiple neurological disorders including epilepsy, Alzheimer's Disease, Parkinson's disease and autism
1. Physiology of Arousal 2. Schizophrenia and Arousal 3. PTSD and Arousal 4. Autism and Arousal 5. Arousal and Drug Abuse 6. Control of Arousal and Movement in Neurodegenerative Disorders 7. Parkinson's Disease and Arousal 8. Arousal and Narcolepsy 9. Arousal and Alzheimer's Disease 10. Epilepsy and Arousal 11. Future of Neuroscience and its Social Impact
Dr. Edgar Garcia-Rill is a Professor of Neurobiology and Developmental Sciences, and Psychiatry in the College of Medicine at the University of Arkansas for Medical Sciences (UAMS). He also holds graduate faculty appointments in the Neurobiology and Developmental Sciences and Interdisciplinary Biomedical Sciences program. He is the Director of the Center for Translational Neuroscience, a Center of Biomedical Research Excellence.