Drug Overview
Pomalyst (pomalidomide; Celgene) is an oral class I thalidomide analog, immunomodulatory drug with antineoplastic activity.
In vitro studies have shown that the drug acts through multiple mechanisms. Evidence suggests that in addition to anti-angiogenic effects, Pomalyst inhibits proliferation and induces apoptosis of hematopoietic tumor cells, and may have antineoplastic effects. Pomalyst also enhanced T cell- and natural killer cell-mediated immunity and inhibited production of pro-inflammatory cytokines by monocytes.
Pomalyst (pomalidomide; Celgene) is an oral class I thalidomide analog, immunomodulatory drug with antineoplastic activity.
In vitro studies have shown that the drug acts through multiple mechanisms. Evidence suggests that in addition to anti-angiogenic effects, Pomalyst inhibits proliferation and induces apoptosis of hematopoietic tumor cells, and may have antineoplastic effects. Pomalyst also enhanced T cell- and natural killer cell-mediated immunity and inhibited production of pro-inflammatory cytokines by monocytes.
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