The publisher explores Roche’s prescription pharmaceutical performance and outlook over 2019–29.
Snapshot
Model updates (24 July 2020)
Model updates (3 June 2020)
Model updates (4 March 2020)
Model updates (17 October 2019)
Model updates (16 August 2019)
Snapshot
- Overview: Roche is poised to grow despite significant biosimilar headwinds to legacy franchises, with several new blockbusters and a strong late-stage pipeline.
- Key themes: [1] Roche will see near-term growth even as key franchises encounter heavy biosimilar competition, as recent launches have been very strong [2] Ocrevus, Perjeta, Tecentriq, and Hemlibra are all seeing rapid growth at blockbuster levels [3] Roche’s recent string of acquisitions reflects the company’s ambition to reinforce its dominance in oncology, in anticipation of biosimilar erosion of its leading brands.
Model updates (24 July 2020)
- Avastin forecast adjusted lower due to higher-than-expected biosimilar impact
- Rituxan forecast adjusted lower due to higher-than-expected biosimilar impact
- Actemra forecast adjusted higher due to COVID-19 benefits
- Ocrevus forecast adjusted lower due to COVID-19 impacts to new patient starts in MS
- Lucentis forecast adjusted lower due to COVID-19 impact on ophthalmology patient access
- Pralsetinib forecast added due to in-licensing of asset from Blueprint Medicines
- Satralizumab name changed to Enspryng due to approval in Japan.
Model updates (3 June 2020)
- Avastin forecast adjusted lower due to biosimilar impact in the US
- Rozlytrek forecast adjusted lower due to launch trend
- Herceptin forecast adjusted lower due to biosimilar impact in the US
- Ocrevus forecast adjusted higher due to strong demand trends and continued market share gains
- Polivy forecast adjusted higher due to initial launch in Europe.
Model updates (4 March 2020)
- Rituxan forecast adjusted higher due to lower-than-expected initial impact from biosimilar launches in the US
- Herceptin forecast adjusted lower due to continued generic erosion and patients switching to Kadcyla
- Perjeta forecast adjusted higher due to increased patient demand for adjuvant early breast cancer
- Ocrevus forecast adjusted higher due to continued uptake across all types of multiple sclerosis and gains in earlier lines of therapy
- Tecentriq forecast adjusted higher due to uptake in extensive-stage small cell lung cancer and triple-negative breast cancer, in addition to first-line non-small cell lung cancer
- Kadcyla forecast adjusted higher due to adjuvant treatment and switching from Herceptin
- Hemlibra forecast adjusted higher due to continued share gains in non-inhibitors and inhibitors
- Alecensa forecast adjusted higher due to growth in first-line ALK+ non-small cell lung cancer and NDRL listing in China
- Rozlytrek forecast adjusted lower due to slower-than-expected launch
- Polivy forecast adjusted higher due to stronger-than-expected launch
- Satralizumab forecast added
- SPK-8011 forecast added
- SRP-9001 forecast added after $1.15bn upfront licensing deal with Sarepta.
Model updates (17 October 2019)
- Avastin forecast adjusted higher due to stronger sales in Rest of World, with notable growth in China driven by first-line CRC and NSCLC, along with longer duration of treatment
- Perjeta forecast adjusted higher due to growth driven by early breast cancer (eBC) adjuvant setting
- Tecentriq forecast adjusted higher due to growth in first-line NSCLC and launches in first-line SCLC and first-line TNBC
- Kadcyla forecast adjusted higher due to stronger-than-expected initial uptake in the US after real-time oncology review approval in HER2-positive eBC
- Hemlibra forecast adjusted higher due to strong uptake in the US and Japan in non-inhibitors.
Model updates (16 August 2019)
- Avastin forecast adjusted higher due to lower-than-expected biosimilar impact in 2019
- Ocrevus forecast adjusted higher due to continued strong adoption in the US
- Tecentriq forecast adjusted higher due to rapid uptake in triple-negative breast cancer and extensive-stage small cell lung cancer
- Kadcyla forecast adjusted higher due to initial uptake in the US after real-time oncology review approval in HER2-positive eBC
- Hemlibra forecast adjusted higher due to strong uptake globally
- Alecensa forecast adjusted lower due to less share gain in first-line NSCLC than anticipated
- Rozlytrek (entrectinib) forecast added
- Polivy (polatuzumab vedotin) forecast added
- Idasanutlin forecast added
- Ipatasertib forecast added
- Faricimab forecast added
- Satralizumab forecast added
- Risdiplam forecast added.
Table of Contents
Company Background
Recent Earnings Review
Company Forecast
Company Profile
Clinical Trial Overview