Drug Overview
Vertex is developing several triple combination regimens in order to further its cystic fibrosis portfolio with the best such regimen, combining a new CFTR corrector compound with its tezacaftor + ivacaftor backbone, which is now approved as Symdeko. New CFTR correctors evaluated so far include VX-152, VX-440, VX-445, and VX-659, with Vertex targeting VX-445 and VX-659 for further development.
Vertex is developing several triple combination regimens in order to further its cystic fibrosis portfolio with the best such regimen, combining a new CFTR corrector compound with its tezacaftor + ivacaftor backbone, which is now approved as Symdeko. New CFTR correctors evaluated so far include VX-152, VX-440, VX-445, and VX-659, with Vertex targeting VX-445 and VX-659 for further development.
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OVERVIEW
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