1. PREFACE
1.1. Scope of the Report
1.2. Research Methodology
1.3. Chapter Outlines
2. EXECUTIVE SUMMARY3. INTRODUCTION
3.1. Chapter Overview
3.2. Classification of Vaccines based on the Type of Active Ingredient
3.2.1. Live, Attenuated Vaccines
3.2.2. Inactivated Vaccines
3.2.3. Subunit Vaccines
3.2.4. Toxoid Vaccines
3.2.5. DNA Vaccines
3.3. Key Components within Vaccine Formulations
3.4. Vaccine Development and Manufacturing
3.4.1. Identification of Antigen and Manufacturing Process Development
3.4.2. Production of Vaccines in Different Expression System
3.4.2.1. Bacterial Expression System
3.4.2.2. Yeast Expression System
3.4.2.3. Insect Expression
3.4.2.4. Embryonated Chicken Eggs and Primary Chicken Embryonic Fibroblasts (CEFs)
3.4.2.5. Plant Expression Systems
3.4.2.6. Avian Expression Systems
3.4.2.7. Mammalian Expression Systems
3.4.3. Vaccine Manufacturing Process
3.4.3.1. Upstream Process
3.4.3.2. Downstream Process
3.4.3.3. Formulation and Fill / Finish
3.4.4. Clinical Development and Approval
3.4.5. Vaccine Supply Chain and Logistics
3.5. Vaccine Contract Manufacturing
3.5.1. Need for Outsourcing Vaccine Manufacturing Operations
3.5.2. Commonly Outsourced Operations
3.5.3. Selecting a CMO Partner
3.5.4. Advantages of Outsourcing Manufacturing Operations
3.5.5. Risk Factors and Challenges
4. COMPETITIVE LANDSCAPE
4.1. Chapter Overview
4.2. Vaccine Contract Manufacturers: Overall Market Landscape
4.2.1. Analysis by Year of Establishment
4.2.2. Analysis by Size of Employee Base
4.2.3. Analysis by Location of Headquarters
4.2.4. Analysis by Location of Manufacturing Facilities
4.2.5. Analysis by Type of Services Offered
4.2.6. Analysis by Scale of Operation
4.2.7. Analysis by Expression System Used
4.2.8. Analysis by Type of Vaccines Manufactured
5. COMPANY COMPETITIVE ANALYSIS
5.1. Chapter Overview
5.2. Methodology
5.3. Assumptions and Key Input Parameters
5.4. Competitiveness Analysis: Vaccine Contract Manufacturers in North America
5.4.1. Companies Offering Contract Vaccine Manufacturing Services based on Mammalian Expression System
5.4.2. Companies Offering Contract Vaccine Manufacturing Services based on Microbial Expression System
5.4.3. Companies Offering Contract Vaccine Manufacturing Services based on Other Expression System
5.5. Competitiveness Analysis: Vaccine Contract Manufacturers in Europe
5.5.1. Companies Offering Contract Vaccine Manufacturing Services based on Mammalian Expression System
5.5.2. Companies Offering Contract Vaccine Manufacturing Services based on Microbial Expression System
5.5.3. Companies Offering Contract Vaccine Manufacturing Services based on Other Expression System
5.6. Competitiveness Analysis: Vaccine Contract Manufacturers in Asia-Pacific and Rest of the World
5.6.1. Companies Offering Contract Vaccine Manufacturing Services based on Mammalian Expression System
5.6.2. Companies Offering Contract Vaccine Manufacturing Services based on Microbial Expression System
5.6.3. Companies Offering Contract Vaccine Manufacturing Services based on Other Expression System
6. VACCINE CONTRACT MANUFACTURING IN NORTH AMERICA
6.1. Chapter Overview
6.2. Albany Molecular Research (AMRI) / OSO BioPharmaceuticals Manufacturing (OsoBio)
6.2.1. Company Overview
6.2.2. Financial Information
6.2.3. Vaccine Manufacturing Services Portfolio
6.2.3.1. Fill / Finish Services
6.2.3.2. Regulatory Support and Quality Assurance Services
6.2.4. Vaccine Manufacturing Facilities
6.2.6. Recent Developments
6.2.6.1. Partnerships
6.2.6.2. Expansions
6.2.6.3. Awards and Accolades
6.2.7. Future Outlook
6.3. Catalent Biologics
6.3.1. Company Overview
6.3.2. Financial Information
6.3.3. Vaccine Manufacturing Services Portfolio
6.3.3.1. Cell Line Development Services
6.3.3.2. Clinical Manufacturing Services
6.3.3.3. Analytical Services
6.3.3.4. Clinical Supply Services
6.3.3.5. Regulatory Support Services
6.3.4. Vaccine Manufacturing Facilities
6.3.5. Recent Developments
6.3.5.1. Partnerships
6.3.5.2. Expansions
6.3.5.3. Awards and Accolades
6.3.6. Future Outlook
6.4. Charles River Laboratories
6.4.1. Company Overview
6.4.2. Financial Information
6.4.3. Vaccine Manufacturing Services Portfolio
6.4.3.1. Vaccine Development Services
6.4.3.2. Vaccine Manufacturing Services
6.4.3.3. Avian Vaccine Services
6.4.4. Vaccine Manufacturing Facilities
6.4.5. Recent Developments
6.4.5.1. Partnerships
6.4.5.2. Expansions
6.4.6. Future Outlook
6.5. Meridian Life Science (MLS)
6.5.1. Company Overview
6.5.2. Financial Information
6.5.3. Vaccine Manufacturing Services Portfolio
6.5.3.1. Cell and Virus Banking Services
6.5.3.2. Process development and Scale-up Services
6.5.3.3. Formulation Development and Fill/finish Services
6.5.3.4. Regulatory Support Services
6.5.4. Vaccine Manufacturing Facilities
6.5.5. Recent Developments
6.5.5.1. Partnerships
6.5.5.2. Awards and Accolades
6.5.6. Future Outlook
6.6. BioReliance (A Unit of Merck)
6.6.1. Company Overview
6.6.2. Financial Information
6.6.3. Vaccine Manufacturing Services Portfolio
6.6.3.1. cGMP Cell and Virus Banking Services
6.6.3.2. Process Development Services
6.6.3.3. Biorepository Services
6.6.3.4. Contract Manufacturing Support Services
6.6.4. Vaccine Manufacturing Facilities
6.6.5. Recent Developments
6.6.5.1. Partnerships
6.6.5.2. Expansions
6.6.5.3. Awards and Accolades
6.6.6. Future Outlook
7. VACCINE CONTRACT MANUFACTURING IN EUROPE
7.1. Chapter Overview
7.2. Cobra Biologics
7.2.1. Company Overview
7.2.2. Vaccine Manufacturing Services Portfolio
7.2.2.1. Viral Vaccines and Virus based Services
7.2.2.2. DNA Vaccines and DNA based Services
7.2.2.3. Other Services
7.2.3. Vaccine Manufacturing Facilities
7.2.4. Recent Developments
7.2.4.1. Partnerships
7.2.4.2. Expansions
7.2.5. Future Outlook
7.3. Eurogentec
7.3.1. Company Overview
7.3.2. Vaccine Manufacturing Services Portfolio
7.3.2.1. Manufacturing Services
7.3.2.2. Analytical and Regulatory Support Services
7.3.2.3. Other Services
7.3.3. Future Outlook
7.4. IDT Biologika
7.4.1. Company Overview
7.4.2. Vaccine Manufacturing Services Portfolio
7.4.2.1. Development Services
7.4.2.2. Vaccine Manufacturing Services
7.4.2.3. Fill / Finish Services
7.4.2.4. Labeling and Packaging Services
7.4.2.5. Storage Services
7.4.2.6. Quality Control Services
7.4.3. Vaccine Manufacturing Facilities
7.4.4. Recent Developments
7.4.4.1. Partnerships
7.4.4.2. Expansions
7.4.4.3. Awards and Accolades
7.4.5. Future Outlook
7.6. Lonza
7.6.1. Company Overview
7.6.2. Financial Information
7.6.3. Vaccine Manufacturing Services Portfolio
7.6.3.1. Process Development and Optimization Services
7.6.3.2. Vaccine Commercial Manufacturing Services
7.6.3.3. Fill / Finish Services
7.6.3.4. Other Services
7.6.4. Recent Developments
7.6.4.1. Partnerships
7.6.4.2. Expansions
7.6.4.3. Awards and Accolades
7.6.5. Future Outlook
8. VACCINE CONTRACT MANUFACTURING IN ASIA PACIFIC AND THE REST OF THE WORLD
8.1. Chapter Overview
8.2. GreenPak Biotech
8.2.1. Company Overview
8.2.2. Vaccine Manufacturing Services Portfolio
8.3. Hong Kong Institute of Biotechnology
8.3.1. Company Overview
8.3.2. Vaccine Manufacturing Services Portfolio
8.3.2.1. Manufacturing Services
8.3.3. Vaccine Manufacturing Facilities
8.4. WuXi AppTec ((WuXi Biologics)
8.4.1. Company Overview
8.4.2. Financial Information
8.4.3. Vaccine Manufacturing Services Portfolio
8.4.3.1. Non-Clinical Services
8.4.3.2. Discovery and Early Diagnostic Testing Services
8.4.3.3. Support Services
8.4.3.4. Manufacturing Services
8.4.3.5. Vaccine Testing Services
8.4.4. Recent Developments
8.4.4.1. Partnerships
8.4.4.2. Awards and Accolades
8.4.5. Future Outlook
8.5. Bharat Biotech
8.5.1. Company Overview
8.5.2. Vaccine Manufacturing Services Portfolio
8.5.3. Vaccine Manufacturing Facilities
8.5.4. Recent Developments
8.5.4.1. Partnerships
8.5.4.2. Awards and Accolades
8.5.5. Future Outlook
8.6. Biological E
8.6.1. Company Overview
8.6.2. Vaccine Manufacturing Services Portfolio
8.6.3. Vaccine Manufacturing Facilities
8.6.4. Recent Developments
8.6.4.1. Partnerships
8.6.4.2. Expansions
8.6.4.3. Awards and Accolades
8.6.5. Future Outlook
9. PARTNERSHIPS AND COLLABORATIONS
9.1. Chapter Overview
9.2. Partnership Models
9.3. Vaccine Contract Manufacturing: List of Partnerships and Collaborations
9.3.1. Analysis by Year of Partnership
9.3.2. Analysis by Type of Partnership
9.3.3. Analysis by Focus Area
9.3.4. Analysis by Scale of Operation
9.3.5. Most Active Players: Analysis by Number of Partnerships
9.3.6. Regional Analysis
9.3.6.1. Intercontinental and Intracontinental Agreements
10. RECENT EXPANSIONS
10.1. Chapter Overview
10.1.1. Vaccine Contract Manufacturing Service Providers: Recent Expansions
10.1.2. Analysis by Year of Expansion
10.1.3. Analysis by Type of Expansion
10.1.4. Analysis by Scale of Operation and Type of Expansion
10.1.5. Analysis by Geographical Distribution
10.1.6. Analysis by Company Headquarters and Company Size
10.1.7. Analysis by Location of Facility and Purpose of Expansion
10.1.8. Analysis by Type of Services Offered
10.1.9. Analysis by Type of Service and Purpose of Expansion
10.1.10. Most Active Players: Analysis by Number of Recent Expansions
11. CAPACITY ANALYSIS
11.1. Chapter Overview
11.2. Assumptions and Methodology
11.3. Vaccine Contract Manufacturing Market: Global Production Capacity (in Liters) 11.3.1.
11.3.2. Analysis by Expression System
11.3.3. Analysis by Scale of Operation
11.3.4. Analysis by Region
11.3.4.1. Production Capacity in North America (in Liters)
11.3.4.2. Production Capacity in Europe (in Liters)
11.3.4.3. Production Capacity in Asia and Middle East (in Liters)
11.4. Conclusion
12. DEMAND ANALYSIS
12.1. Chapter Overview
12.2. Scope and Methodology
12.3. Global Clinical Demand for Vaccines: Analysis by Number of Trials
12.3.1. Analysis by Trial Registration Year
12.3.2. Analysis by Type of Vaccine
12.3.3. Analysis by Clinical Dose
12.3.4. Analysis by Trial Status
12.3.5. Geographical Analysis by Number of Clinical Trials
12.3.6. Geographical Analysis by Trial Status and Trial Phase
12.3.7. Analysis by Type of Sponsors / Collaborators
12.3.8. Most Active Players
12.4. Global Clinical Demand for Vaccines: Analysis by Enrolled Patient Population
12.4.1. Geographical Analysis by Enrolled Patient Population
12.4.2. Geographical Analysis of Enrolled Patient Population by Trial Phase and Type of Vaccine
12.5. Global Clinical Demand for Vaccines: Annual Demand of Vaccines
12.6. Concluding Remarks
13. MARKET FORECAST
13.1. Chapter Overview
13.2. Forecast Methodology and Key Assumptions
13.3. Overall Vaccine Contract Manufacturing Market, 2019-2030
13.4. Vaccine Contract Manufacturing Market, 2019-2030: Distribution by Service Portfolio
13.5. Vaccine Contract Manufacturing Market, 2019-2030: Distribution by Expression System Used
13.6. Vaccine Contract Manufacturing Market, 2019-2030: Distribution by Scale of Operation
13.7. Vaccine Contract Manufacturing Market, 2019-2030: Distribution by Size of Manufacturers
13.8. Vaccine Contract Manufacturing Market, 2019-2030: Distribution by Geography
13.8.1. Vaccine Contract Manufacturing Market in North America, 2019-2030
13.8.1.1. Vaccine Contract Manufacturing Market in the US, 2019-2030
13.8.1.2. Vaccine Contract Manufacturing Market in Rest of North America, 2019-2030
13.8.1.3. Vaccine Contract Manufacturing Market in North America for Mammalian Cell-based Operations, 2019-2030
13.8.1.4. Vaccine Contract Manufacturing Market in North America for Microbial Cell-based Operations, 2019-2030
13.8.1.5. Vaccine Contract Manufacturing Market in North America for Other Expression System-based Operations, 2019-2030
13.8.1.6. Vaccine Contract Manufacturing Market in North America for Preclinical / Clinical Scale Operations, 2019-2030
13.8.1.7. Vaccine Contract Manufacturing Market in North America for Commercial Operations, 2019-2030
13.8.1.8. Vaccine Contract Manufacturing Market in North America for Small-sized Companies, 2019-2030
13.8.1.9. Vaccine Contract Manufacturing Market in North America for Mid-sized Companies, 2019-2030
13.8.1.10. Vaccine Contract Manufacturing Market in North America for Large / Very Large Companies, 2019-2030
13.8.2. Vaccine Contract Manufacturing Market in Europe, 2019-2030
13.8.2.1. Vaccine Contract Manufacturing Market in Italy, 2019-2030
13.8.2.2. Vaccine Contract Manufacturing Market in Germany, 2019-2030
13.8.2.3. Vaccine Contract Manufacturing Market in France, 2019-2030
13.8.2.4. Vaccine Contract Manufacturing Market in Spain, 2019-2030
13.8.2.5. Vaccine Contract Manufacturing Market in the UK, 2019-2030
13.8.2.6. Vaccine Contract Manufacturing Market in Rest of Europe, 2019-2030
13.8.2.7. Vaccine Contract Manufacturing Market in Europe for Mammalian Cell-based Operations, 2019-2030
13.8.2.8. Vaccine Contract Manufacturing Market in Europe for Microbial Cell-based Operations, 2019-2030
13.8.2.9. Vaccine Contract Manufacturing Market in Europe for Other Expression System-based Operations, 2019-2030
13.8.2.10. Vaccine Contract Manufacturing Market in Europe for Preclinical / Clinical Operations, 2019-2030
13.8.2.11. Vaccine Contract Manufacturing Market in Europe for Commercial Operations, 2019-2030
13.8.2.12. Vaccine Contract Manufacturing Market in Europe for Small-sized Companies, 2019-2030
13.8.2.13. Vaccine Contract Manufacturing Market in Europe for Mid-sized Companies, 2019-2030
13.8.2.14. Vaccine Contract Manufacturing Market in Europe for Large / Very Large Companies, 2019-2030
13.8.3. Vaccine Contract Manufacturing Market in Asia and Rest of the World, 2019-2030
13.8.3.1. Vaccine Contract Manufacturing Market in China, 2019-2030
13.8.3.2. Vaccine Contract Manufacturing Market in India, 2019-2030
13.8.3.3. Vaccine Contract Manufacturing Market in South Korea, 2019-2030
13.8.3.4. Vaccine Contract Manufacturing Market in Japan, 2019-2030
13.8.3.5. Vaccine Contract Manufacturing Market in Australia, 2019-2030
13.8.3.6. Vaccine Contract Manufacturing Market in Rest of Asia and Other Regions, 2019-2030
13.8.3.7. Vaccine Contract Manufacturing Market in Asia and Rest of the World for Mammalian Cell-based Operations, 2019-2030
13.8.3.8. Vaccine Contract Manufacturing Market in Asia and Rest of the World for Microbial Cell-based Operations, 2019-2030
13.8.3.9. Vaccine Contract Manufacturing Market in Asia and Rest of the World for Other Expression System-based Operations, 2019-2030
13.8.3.10. Vaccine Contract Manufacturing Market in Asia and Rest of the World for Preclinical / Clinical Operations, 2019-2030
13.8.3.11. Vaccine Contract Manufacturing Market in Asia and Rest of the World for Commercial Operations, 2019-2030
13.8.3.12. Vaccine Contract Manufacturing Market in Asia and Rest of the World for Small-sized Companies, 2019-2030
13.8.3.13. Vaccine Contract Manufacturing Market in Asia and Rest of the World for Mid-sized Companies, 2019-2030
13.8.3.14. Vaccine Contract Manufacturing Market in Asia and Rest of the World for Large / Very Large Companies, 2019-2030
14. SWOT ANALYSIS
14.1 Chapter Overview
14.2. Strengths
14.3. Weaknesses
14.4. Opportunities
14.5. Threats
14.6. Comparison of Swot Factors
14.7. Concluding Remarks
15. FUTURE TRENDS
15.1. Chapter Overview
15.2. Adoption of Innovative Technologies to Drive Growth
15.3. Shift to Single-Use Systems and Components
15.4. The Advent of Virus-like Particles (VLPs)
15.5. Growing Investments in Existing Infrastructure
15.6. Evolving Client / Sponsor and CMO / CDMO Relationships
15.7. Business Acquisition and Consolidation Activity
16. EXECUTIVE INSIGHTS
16.1. Chapter Overview
16.2. Batavia Biosciences
16.2.1 Company Snapshot
16.2.2 Interview Transcript: Menzo Havenga, CEO and Claire Otjes, Marketing Manager
16.3. Goodwin Biotechnology
16.3.1. Company Snapshot
16.3.2 Interview Transcript: David C Cunningham, Director Of Corporate Development
16.4. Statens Serum Institut
16.4.1. Company Snapshot
16.4.2 Interview Transcript: Ingrid Cromann, Director - Vaccine Development
16.5. Novasep Synthesis
16.5.1. Company Snapshot
16.5.2 Interview Transcript: Kevin Daley, Director Pharmaceuticals
16.6. ProBioGen
16.6.1. Company Snapshot
16.6.2 Interview Transcript: Oliver Schub, Senior Business Development Manager
16.7. Wacker Biotech
16.7.1 Company Snapshot
16.7.2 Interview Transcript: Sebastian Schuck, Head of Business Development
17. APPENDIX 1: TABULATED DATA18. APPENDIX 2: LIST OF COMPANIES AND ORGANIZATIONSList of Figures
Figure 3.1 Differences Between Vaccines and Small Molecule Drugs
Figure 3.2 Classification of Vaccines
Figure 3.3 Vaccine Manufacturing Process
Figure 3.4 Key Steps in Vaccine Transportation
Figure 3.5 Types of Third-Party Service Providers in the Pharmaceutical Industry
Figure 3.6 Commonly Outsourced Vaccine Development Operations
Figure 3.7 Key Considerations for Selecting a CMO Partner
Figure 3.8 Risks and Challenges Associated with Contract Manufacturing
Figure 4.1 Vaccine CMOs: Distribution by Year of Establishment
Figure 4.2 Vaccine CMOs: Distribution by Size of Employee Base
Figure 4.3 Vaccine CMOs: Distribution by Location of Headquarters (Region-wise)
Figure 4.4 Vaccine CMOs: Distribution by Location of Headquarters (Country-wise)
Figure 4.5 Vaccine CMOs: Distribution by Location of Manufacturing Facility (Region-wise)
Figure 4.6 Vaccine CMOs: Distribution by Location of Manufacturing Facility (Country-wise)
Figure 4.7 Vaccine CMOs: Distribution by Type of Services Offered
Figure 4.8 Vaccine CMOs: Distribution by Scale of Operation
Figure 4.9 Vaccine CMOs: Distribution by Expression System Used
Figure 4.10 Vaccine CMOs: Distribution by Type of Vaccines Manufactured
Figure 5.1. Competitiveness Analysis of Vaccine Contract Manufacturers in North America
Figure 5.2. Competitiveness Analysis of North American Service Providers Offering Contract Manufacturing of Vaccines based on Mammalian Expression
Figure 5.3. Competitiveness Analysis of North American Service Providers Offering Contract Manufacturing of Vaccines based on Microbial Expression System
Figure 5.4. Competitiveness Analysis of North American Service Providers Offering Contract Manufacturing of Vaccines based on Other Expression System
Figure 5.5. Competitiveness Analysis of Vaccine Contract Manufacturers in Europe
Figure 5.6. Competitiveness Analysis of European Service Providers Offering Contract Manufacturing of Vaccines based on Mammalian Expression System
Figure 5.7. Competitiveness Analysis of European Service Providers Offering Contract Manufacturing of Vaccines based on Microbial Expression System
Figure 5.8. Competitiveness Analysis of European Service Providers Offering Contract Manufacturing of Vaccines based on Other Expression System
Figure 5.9. Competitiveness Analysis of Vaccine Contract Manufacturers in Asia-Pacific
Figure 5.10. Competitiveness Analysis of Asia Pacific Service Providers Offering Contract Manufacturing of Vaccines based on Mammalian Expression System
Figure 5.11. Competitiveness Analysis of Asia Pacific Service Providers Offering Contract Manufacturing of Vaccines based on Microbial Expression System
Figure 5.12. Competitiveness Analysis of Asia Pacific Service Providers Offering Contract Manufacturing of Vaccines based on Other Expression System
Figure 6.1 AMRI: Annual Revenues, 2012- Q1 2017 (USD Million)
Figure 6.2 AMRI: Overview of Service Portfolio
Figure 6.3 Catalent: Revenues, 2013 – Q1 2019 (USD Million)
Figure 6.4 Catalent: Revenues by Business Divisions, 2018 (USD Million)
Figure 6.5 Catalent: Vaccine Manufacturing Services Portfolio
Figure 6.6 Charles River Laboratories: Annual Revenues, 2011–2018 (USD Billion)
Figure 6.7 Charles River Laboratories: Distribution of Revenues by Business Segments, 2018 (USD Billion)
Figure 6.8 Charles River Laboratories: Products and Services
Figure 6.9 Meridian Life Science: Annual Revenues, 2013- H1 2019 (USD Million)
Figure 6.10 Merck: Annual Revenues, 2012 –2018 (EUR Billion)
Figure 6.11 Merck: Distribution of Revenues by Business Segments, 2018 (EUR Billion)
Figure 6.12 SAFC: Contract Manufacturing Support Services
Figure 6.13 SAFC Carlsbad Facility: Vaccine Manufacturing Services
Figure 7.1 Eurogentec: Manufacturing Technologies and Capabilities
Figure 7.2 IDT Biologika: Vaccine-related Service Portfolio
Figure 7.1 Lonza: Annual Revenues, 2012-2018 (CHF Million)
Figure 7.2 Lonza: Vaccine Manufacturing Services Portfolio
Figure 8.1 Hong Kong Institute of Biotechnology: Service Portfolio
Figure 8.2 WuXi Biologics: Annual Revenues, 2014-2018 (RMB Million)
Figure 8.3 WuXi Biologics: Vaccine Development Services
Figure 8.4 WuXi Biologics: Vaccine Testing Services
Figure 9.1 Partnerships and Collaborations: Cumulative Trend by Year, 2013-2019
Figure 9.2 Partnerships and Collaborations: Distribution by Type of Partnership
Figure 9.3 Partnerships and Collaborations: Trend by Type of Partnership and Year (2013-2018)
Figure 9.4 Partnerships and Collaborations: Distribution by Type of Vaccines
Figure 9.5 Partnerships and Collaborations: Distribution by Therapeutic Area and Type of Partnership
Figure 9.6 Partnerships and Collaborations: Distribution by Scale of Operation and Type of Partnership
Figure 9.7 Partnerships and Collaborations: Most Active Players
Figure 9.8 Partnerships and Collaborations: Regional Distribution
Figure 9.9 Partnerships and Collaborations: Intercontinental and Intracontinental Distribution
Figure 10.1 Facility Expansions: Distribution by Year, 2013-2019
Figure 10.2 Facility Expansions: Distribution by Type of Expansion
Figure 10.3 Facility Expansions: Distribution by Scale of Operation and Type of Expansion
Figure 10.4 Facility Expansions: Distribution by Geography and Year, 2013-2019
Figure 10.5 Facility Expansions: Distribution by Company Headquarters and Company Size
Figure 10.6 Facility Expansions: Distribution by Location of Facility and Type of Expansion
Figure 10.7 Facility Expansions: Distribution by Type of Services Offered
Figure 10.8 Facility Expansions: Distribution by Type of Services and Type of Expansion
Figure 10.9 Facility Expansions: Most Active Players
Figure 11.1 Vaccine Contract Manufacturing Market: Global Capacity: Distribution by Range of Installed Capacity
Figure 11.2 Capacity Analysis: Global Vaccine Contract Manufacturing Capacity by Size of CMOs
Figure 11.3 Capacity Analysis: Global Vaccine Contract Manufacturing Capacity based on Expression System
Figure 11.4 Capacity Analysis: Global Vaccine Contract Manufacturing Capacity based on Scale of Manufacturing
Figure 11.5 Capacity Analysis: Regional Distribution of Vaccine CMOs
Figure 11.6 Capacity Analysis: Vaccine Contract Manufacturing Capacity of the US
Figure 11.7 Capacity Analysis: Regional Vaccine Contract Manufacturing Capacity of Canada
Figure 11.8 Capacity Analysis: Regional Vaccine Contract Manufacturing Capacity of the UK
Figure 11.9 Capacity Analysis: Regional Vaccine Contract Manufacturing Capacity of Germany
Figure 11.10 Capacity Analysis: Regional Vaccine Contract Manufacturing Capacity of France
Figure 11.11 Capacity Analysis: Regional Vaccine Contract Manufacturing Capacity of Italy
Figure 11.12 Capacity Analysis: Regional Vaccine Contract Manufacturing Capacity of Spain
Figure 11.13 Capacity Analysis: Regional Vaccine Contract Manufacturing Capacity of rest of Europe
Figure 11.14 Capacity Analysis: Regional Vaccine Contract Manufacturing Capacity of South Korea
Figure 11.15 Capacity Analysis: Regional Vaccine Contract Manufacturing Capacity of India
Figure 11.16 Capacity Analysis: Regional Vaccine Contract Manufacturing Capacity of China
Figure 11.17 Capacity Analysis: Regional Vaccine Contract Manufacturing Capacity of Japan
Figure 11.18 Capacity Analysis: Regional Vaccine Contract Manufacturing Capacity of Rest of Asia and Middle East
Figure 12.1 Global Clinical Demand for Vaccines: Cumulative Distribution of Trials by Registration Year
Figure 12.2 Global Clinical Demand for Vaccines: Distribution of Trials by Type of Vaccines
Figure 12.3 Global Clinical Demand for Vaccines: Distribution of Trials by Phase
Figure 12.4 Global Clinical Demand for Vaccines: Distribution of Trials by Status
Figure 12.5 Global Clinical Demand for Vaccines: Geographical Distribution of Trials (Country-Wise)
Figure 12.6 Global Clinical Demand for Vaccines: Geographical Distribution of Trials by Status and Phase
Figure 12.7 Global Clinical Demand for Vaccines: Distribution of Trials by Type of Sponsors / Collaborators
Figure 12.8 Global Clinical Demand for Vaccines: Most Active Industry Players in Terms of Number of Trials Conducted
Figure 12.9 Global Clinical Demand for Vaccines: Most Active Non-Industry Players in Terms of Number of Trials Conducted
Figure 12.10 Global Clinical Demand for Vaccines: Geographical Distribution of Enrolled Patient Population (Country-Wise)
Figure 12.11 Global Clinical Demand for Vaccines: Geographical Distribution of Enrolled Patient Population by Type of Vaccine
Figure 12.12 Global Clinical Demand for Vaccines: Annual Demand for Vaccines (in Liters)
Figure 13.1 Overall Vaccine Contract Manufacturing Market, 2019-2030 (USD Million)
Figure 13.2 Vaccine Contract Manufacturing Market, 2019-2030: Distribution by Type of Services Offered (USD Billion)
Figure 13.3 Vaccine Contract Manufacturing Market, 2019-2030: Distribution by Expression System Used (USD Million)
Figure 13.4 Vaccine Contract Manufacturing Market, 2019-2030: Distribution by Scale of Operation (USD Million)
Figure 13.5 Vaccine Contract Manufacturing Market, 2019-2030: Distribution by Size of Employee Base of Contract Manufacturers (USD Million)
Figure 13.6 Vaccine Contract Manufacturing Market, 2019-2030: Distribution by Geography (USD Million)
Figure 13.7 Vaccine Contract Manufacturing Market in North America, 2019-2030 (USD Million)
Figure 13.8 Vaccine Contract Manufacturing Market in the US, 2019-2030 (USD Million)
Figure 13.9 Vaccine Contract Manufacturing Market in Rest of North America, 2019-2030 (USD Million)
Figure 13.10 Vaccine Contract Manufacturing Market in North America for Mammalian Cell-based Operations, 2019-2030 (USD Million)
Figure 13.11 Vaccine Contract Manufacturing Market in North America for Microbial Cell-based Operations, 2019-2030 (USD Million)
Figure 13.12 Vaccine Contract Manufacturing Market in North America for Other Expression System-based Operations, 2019-2030 (USD Million)
Figure 13.13 Vaccine Contract Manufacturing Market in North America for Preclinical / Clinical Scale Operations, 2019-2030 (USD Million)
Figure 13.14 Vaccine Contract Manufacturing Market in North America for Commercial Operations, 2019-2030 (USD Million)
Figure 13.15 Vaccine Contract Manufacturing Market in North America for Small-sized Companies, 2019-2030 (USD Million)
Figure 13.16 Vaccine Contract Manufacturing Market in North America for Mid-sized Companies, 2019-2030 (USD Million)
Figure 13.17 Vaccine Contract Manufacturing Market in North America for Large / Very Large Companies, 2019-2030 (USD Million)
Figure 13.18 Vaccine Contract Manufacturing Market in Europe, 2019-2030 (USD Million)
Figure 13.19 Vaccine Contract Manufacturing Market in Italy, 2019-2030 (USD Million)
Figure 13.20 Vaccine Contract Manufacturing Market in Germany, 2019-2030 (USD Million)
Figure 13.21 Vaccine Contract Manufacturing Market in France, 2019-2030 (USD Million)
Figure 13.22 Vaccine Contract Manufacturing Market in Spain, 2019-2030 (USD Million)
Figure 13.23 Vaccine Contract Manufacturing Market in the UK, 2019-2030 (USD Million)
Figure 13.24 Vaccine Contract Manufacturing Market in Rest of Europe, 2019-2030 (USD Million)
Figure 13.25 Vaccine Contract Manufacturing Market in Europe for Mammalian Cell-based Operations, 2019-2030 (USD Million)
Figure 13.26 Vaccine Contract Manufacturing Market in Europe for Microbial Cell-based Operations, 2019-2030 (USD Million)
Figure 13.27 Vaccine Contract Manufacturing Market in Europe for Other Expression System-based Operations, 2019-2030 (USD Million)
Figure 13.28 Vaccine Contract Manufacturing Market in Europe for Preclinical / Clinical Operations, 2019-2030 (USD Million)
Figure 13.29 Vaccine Contract Manufacturing Market in Europe for Commercial Operations, 2019-2030 (USD Million)
Figure 13.30 Vaccine Contract Manufacturing Market in Europe for Small-sized Companies, 2019-2030 (USD Million)
Figure 13.31 Vaccine Contract Manufacturing Market in Europe for Mid-sized Companies, 2019-2030 (USD Million)
Figure 13.32 Vaccine Contract Manufacturing Market in Europe for Large / Very Large Companies, 2019-2030 (USD Million)
Figure 13.33 Vaccine Contract Manufacturing Market in Asia and Rest of the World, 2019-2030 (USD Million)
Figure 13.34 Vaccine Contract Manufacturing Market in China, 2019-2030 (USD Million)
Figure 13.35 Vaccine Contract Manufacturing Market in India, 2019-2030 (USD Million)
Figure 13.36 Vaccine Contract Manufacturing Market in South Korea, 2019-2030 (USD Million)
Figure 13.37 Vaccine Contract Manufacturing Market in Japan, 2019-2030 (USD Million)
Figure 13.38 Vaccine Contract Manufacturing Market in Australia, 2019-2030 (USD Million)
Figure 13.39 Vaccine Contract Manufacturing Market in Rest of Asia and Other Regions, 2019-2030 (USD Million)
Figure 13.40 Vaccine Contract Manufacturing Market in Asia and Rest of the World for Mammalian Cell-based Operations, 2019-2030 (USD Million)
Figure 13.41 Vaccine Contract Manufacturing Market in Asia and Rest of the World for Microbial Cell-based Operations, 2019-2030 (USD Million)
Figure 13.42 Vaccine Contract Manufacturing Market in Asia and Rest of the World for Other Expression System-based Operations, 2019-2030 (USD Million)
Figure 13.43 Vaccine Contract Manufacturing Market in Asia and Rest of the World for Preclinical / Clinical Operations, 2019-2030 (USD Million)
Figure 13.44 Vaccine Contract Manufacturing Market in Asia and Rest of the World for Commercial Operations, 2019-2030 (USD Million)
Figure 13.45 Vaccine Contract Manufacturing Market in Asia and Rest of the World for Small-sized Companies, 2019-2030 (USD Million)
Figure 13.46 Vaccine Contract Manufacturing Market in Asia and Rest of the World for Mid-sized Companies, 2019-2030 (USD Million)
Figure 13.47 Vaccine Contract Manufacturing Market in Asia and Rest of the World for Large / Very Large Companies, 2019-2030 (USD Million)
Figure 14.1 Vaccine Contract Manufacturing: SWOT Analysis
Figure 14.2 Comparison of SWOT Factors: Harvey Ball Analysis
List of Tables
Table 3.1 Classification of Vaccines based on Method of Development
Table 3.2 Live Attenuated Vaccines: Commonly Reported Adverse Events
Table 3.3 Inactivated Vaccines: Commonly Reported Adverse Events
Table 3.4 Subunit Vaccines: Commonly Reported Adverse Events
Table 3.5 Toxoid Vaccines: Commonly Reported Adverse Events
Table 3.6 Vaccine Excipients and their Functions
Table 4.1 Vaccine Contract Manufacturers: List of Service Providers
Table 4.2 Vaccine CMOs: Information on Type of Services Offered
Table 4.3 Vaccine CMOs: Information on Scale of Operation
Table 4.4 Vaccine CMOs: Information on Expression System Used
Table 4.5 Vaccine CMOs: Information on Type of Vaccines Manufactured
Table 6.1 Vaccine CMOs: List of Profiled Companies (North America)
Table 6.2 AMRI (OsoBio): Company Overview
Table 6.3 AMRI (OsoBio): Recent Partnerships
Table 6.4 Catalent Biologics: Company Overview
Table 6.5 Catalent: Biologics Manufacturing and Laboratory Facilities
Table 6.6 Catalent: Recent Partnerships
Table 6.7 Charles River Laboratories: Recent Partnerships
Table 6.8 Charles River Laboratories: Future Outlook
Table 6.9 Meridian Life Science: Recent Partnerships
Table 6.10 BioReliance: Company Overview
Table 6.11 Merck: Recent Partnerships
Table 7.1 Vaccine CMOs: List of Profiled Companies (Europe)
Table 7.2 Cobra Biologics: Recent Partnerships
Table 7.3 IDT Biologika: Recent Partnerships
Table 7.4 Lonza: Company Overview
Table 7.5 Lonza: Recent Partnerships
Table 8.1 Vaccine CMOs: List of Profiled Companies (Emerging Regions)
Table 8.2 Hong Kong Institute of Biotechnology: Vaccine Contract Manufacturing Services
Table 8.3 WuXi Biologics: Biologics Development and Manufacturing Services
Table 8.4 WuXi Biologics: Recent Partnerships
Table 8.5 Bharat Biotech: Recent Partnerships
Table 8.6 Biological E: Recent Partnerships
Table 9.1 Vaccine Contract Manufacturing Market: Partnerships and Collaborations, 2013-2019
Table 10.1 Vaccine Contract Manufacturing Market: List of Recent Expansions, 2013-2019
Table 10.2 Expansions: Information on Types of Services
Table 14.1 Capacity Analysis: CMO Size Adjustments based on Capacity
Table 14.2 Capacity Analysis: CMO Size Adjustments based on Size of Employee Base
Table 14.3 Capacity Analysis: Key Assumptions and Inputs
Table 14.4 Capacity Analysis: Global Contract Vaccine Manufacturing Capacity
Table 14.5 Capacity Analysis: Regional Contract Vaccine Manufacturing Capacity
Table 17.1 Vaccine CMOs: Distribution by Year of Establishment
Table 17.2 Vaccine CMOs: Distribution by Size of Employee Base
Table 17.3 Vaccine CMOs: Distribution by Location of Headquarters (Region-wise)
Table 17.4 Vaccine CMOs: Distribution by Location of Headquarters (Country-wise)
Table 17.5 Vaccine CMOs: Distribution by Location of Manufacturing Facility (Region-wise)
Table 17.6 Vaccine CMOs: Distribution by Location of Manufacturing Facility (Country-wise)
Table 17.7 Vaccine CMOs: Distribution by Type of Services Offered
Table 17.8 Vaccine CMOs: Distribution by Scale of Operation
Table 17.9 Vaccine CMOs: Distribution by Expression System Used
Table 17.10 Vaccine CMOs: Distribution by Type of Vaccines Manufactured
Table 17.11 AMRI: Annual Revenues (USD Million)
Table 17.12 Catalent: Annual Revenues (USD Million)
Table 17.13 Catalent: Annual Revenues by Business Divisions (USD Million)
Table 17.14 Charles River Laboratories: Annual Revenues (USD Billion)
Table 17.15 Charles River Laboratories: Distribution of Revenues by Business Segments (USD Billion)
Table 17.16 Meridian Life Science: Annual Revenues (USD Million)
Table 17.17 Merck: Annual Revenues (EUR Billion)
Table 17.18 Lonza: Annual Revenues (CHF Billion)
Table 17.19 Wuxi Biologics: Annual Revenues (RMB Million)
Table 17.20 Wuxi Biologics: Annual Revenues by Regions of Operation (RMB million)
Table 17.21. Partnerships and Collaborations: Distribution by Year, 2013-2019
Table 17.22. Partnerships and Collaborations: Distribution by Type of Partnership
Table 17.23. Partnerships and Collaborations: Distribution by Type of Partnership and Year
Table 17.24. Partnerships and Collaborations: Distribution by Type of Vaccines
Table 17.25. Partnerships and Collaborations: Distribution by Therapeutic Area and Type of Partnership
Table 17.26. Partnerships and Collaborations: Distribution by Scale of Operation and Type of Partnership
Table 17.27. Partnerships and Collaborations: Most Active Players
Table 17.28. Partnerships and Collaborations: Distribution by Geographical Location
Table 17.29. Facility Expansions: Distribution by Year, 2013-2019
Table 17.30. Facility Expansions: Distribution by Type of Expansion
Table 17.31. Facility Expansions: Distribution by Scale of Operation and Type of Expansion
Table 17.32. Facility Expansions: Distribution by Distribution by Company Headquarters and Company Size
Table 17.33. Facility Expansions: Distribution by Location of Facility and Type of Expansion
Table 17.34. Facility Expansions: Distribution by Types of Services Offered
Table 17.35. Facility Expansions: Distribution by Types of Services and Type of Expansion
Table 17.36. Facility Expansions: Most Active Players
Table 17.37 Capacity Analysis: Global Contract Biomanufacturing Capacity by Size of CMOs
Table 17.38 Capacity Analysis: Global Vaccine Contract Manufacturing Capacity based on Expression System
Table 17.39 Capacity Analysis: Global Vaccine Contract Manufacturing Capacity based on Scale of Manufacturing
Table 17.40 Overall Vaccine Contract Manufacturing Market, 2019-2030 (USD Million)
Table 17.41 Vaccine Contract Manufacturing Market, 2019-2030: Distribution by Type of Services Offered (USD Billion)
Table 17.42 Vaccine Contract Manufacturing Market, 2019-2030: Distribution by Expression System Used (USD Billion)
Table 17.43 Vaccine Contract Manufacturing Market, 2019-2030: Distribution by Scale of Operation (USD Billion)
Table 17.44 Vaccine Contract Manufacturing Market, 2019-2030: Distribution by Size of Employee Base of Contract Manufacturers (USD Billion)
Table 17.45 Vaccine Contract Manufacturing Market, 2019-2030: Distribution by Geography (USD Billion)
Table 17.46 Vaccine Contract Manufacturing Market in North America, 2019-2030 (USD Million)
Table 17.47 Vaccine Contract Manufacturing Market in the US, 2019-2030 (USD Million)
Table 17.48 Vaccine Contract Manufacturing Market in Rest of North America, 2019-2030 (USD Million)
Table 17.49 Vaccine Contract Manufacturing Market in North America for Mammalian Cell-based Operations, 2019-2030 (USD Million)
Table 17.50 Vaccine Contract Manufacturing Market in North America for Microbial Cell-based Operations, 2019-2030 (USD Million)
Table 17.51 Vaccine Contract Manufacturing Market in North America for Other Expression System-based Operations, 2019-2030 (USD Million)
Table 17.52 Vaccine Contract Manufacturing Market in North America for Preclinical / Clinical Scale Operations, 2019-2030 (USD Million)
Table 17.53 Vaccine Contract Manufacturing Market in North America for Commercial Operations, 2019-2030 (USD Million)
Table 17.54 Vaccine Contract Manufacturing Market in North America for Small-sized Companies, 2019-2030 (USD Million)
Table 17.55 Vaccine Contract Manufacturing Market in North America for Mid-sized Companies, 2019-2030 (USD Million)
Table 17.56 Vaccine Contract Manufacturing Market in North America for Large / Very Large Companies, 2019-2030 (USD Million)
Table 17.57 Vaccine Contract Manufacturing Market in Europe, 2019-2030 (USD Million)
Table 17.58 Vaccine Contract Manufacturing Market in Italy, 2019-2030 (USD Million)
Table 17.59 Vaccine Contract Manufacturing Market in Germany, 2019-2030 (USD Million)
Table 17.60 Vaccine Contract Manufacturing Market in France, 2019-2030 (USD Million)
Table 17.61 Vaccine Contract Manufacturing Market in Spain, 2019-2030 (USD Million)
Table 17.62 Vaccine Contract Manufacturing Market in the UK, 2019-2030 (USD Million)
Table 17.63 Vaccine Contract Manufacturing Market in Rest of Europe, 2019-2030 (USD Million)
Table 17.64 Vaccine Contract Manufacturing Market in Europe for Mammalian Cell-based Operations, 2019-2030 (USD Million)
Table 17.65 Vaccine Contract Manufacturing Market in Europe for Microbial Cell-based Operations, 2019-2030 (USD Million)
Table 17.66 Vaccine Contract Manufacturing Market in Europe for Other Expression System-based Operations, 2019-2030 (USD Million)
Table 17.67 Vaccine Contract Manufacturing Market in Europe for Preclinical / Clinical Operations, 2019-2030 (USD Million)
Table 17.68 Vaccine Contract Manufacturing Market in Europe for Commercial Operations, 2019-2030 (USD Million)
Table 17.69 Vaccine Contract Manufacturing Market in Europe for Small-sized Companies, 2019-2030 (USD Million)
Table 17.70 Vaccine Contract Manufacturing Market in Europe for Mid-sized Companies, 2019-2030 (USD Million)
Table 17.71 Vaccine Contract Manufacturing Market in Europe for Large / Very Large Companies, 2019-2030 (USD Million)
Table 17.72 Vaccine Contract Manufacturing Market in Asia and Rest of the World, 2019-2030 (USD Million)
Table 17.73 Vaccine Contract Manufacturing Market in China, 2019-2030 (USD Million)
Table 17.74 Vaccine Contract Manufacturing Market in India, 2019-2030 (USD Million)
Table 17.75 Vaccine Contract Manufacturing Market in South Korea, 2019-2030 (USD Million)
Table 17.76 Vaccine Contract Manufacturing Market in Japan, 2019-2030 (USD Million)
Table 17.77 Vaccine Contract Manufacturing Market in Australia, 2019-2030 (USD Million)
Table 17.78 Vaccine Contract Manufacturing Market in Rest of Asia and Other Regions, 2019-2030 (USD Million)
Table 17.79 Vaccine Contract Manufacturing Market in Asia and Rest of the World for Mammalian Cell-based Operations, 2019-2030 (USD Million)
Table 17.80 Vaccine Contract Manufacturing Market in Asia and Rest of the World for Microbial Cell-based Operations, 2019-2030 (USD Million)
Table 17.81 Vaccine Contract Manufacturing Market in Asia and Rest of the World for Other Expression System-based Operations, 2019-2030 (USD Million)
Table 17.82 Vaccine Contract Manufacturing Market in Asia and Rest of the World for Preclinical / Clinical Operations, 2019-2030 (USD Million)
Table 17.83 Vaccine Contract Manufacturing Market in Asia and Rest of the World for Commercial Operations, 2019-2030 (USD Million)
Table 17.84 Vaccine Contract Manufacturing Market in Asia and Rest of the World for Small-sized Companies, 2019-2030 (USD Million)
Table 17.85 Vaccine Contract Manufacturing Market in Asia and Rest of the World for Mid-sized Companies, 2019-2030 (USD Million)
Table 17.86 Vaccine Contract Manufacturing Market in Asia and Rest of the World for Large / Very Large Companies, 2019-2030 (USD Million)