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Pan-genomics: Applications, Challenges, and Future Prospects

  • ID: 4806637
  • Book
  • 600 Pages
  • Elsevier Science and Technology
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Pan-genomics: Applications, Challenges, and Future Prospects covers current approaches, challenges and future prospects of pan-genomics. The book discusses bioinformatics tools and their applications and focuses on bacterial comparative genomics in order to leverage the development of precise drugs and treatments for specific organisms. The book is divided into three sections: the first, an "overview of pan-genomics and common approaches,” brings the main concepts and current approaches on pan-genomics research; the second, "case studies in pan-genomics,” thoroughly discusses twelve case, and the last, "current approaches and future prospects in pan-multiomics”, encompasses the developments on omics studies to be applied on bacteria related studies.

This book is a valuable source for bioinformaticians, genomics researchers and several members of biomedical field interested in understanding further bacterial organisms and their relationship to human health.

  • Covers the entire spectrum of pangenomics, highlighting the use of specific approaches, case studies and future perspectives
  • Discusses current bioinformatics tools and strategies for exploiting pangenomics data
  • Presents twelve case studies with different organisms in order to provide the audience with real examples of pangenomics applicability
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1. Overview, applications, and future perspectives of Pan-genomics 2. Bioinformatics approaches applied in Pan-genomics and their challenges 3. Evolutionary pan-genomics and applications 4. Insights into old and new enemies: Pan-genomics of Corynebacterium diphtheriae and Corynebacterium ulcerans 5. Pan-genomics of Veterinary pathogens: Corynebacterium psedotuberculosis 6. Pan-genomics of Plant pathogens and its applications 7. Pan-genomics food pathogens and its applications 8. Pan-genomics of aquatic animal pathogens and its applications 9. Pan-genomics of model bacteria and their outcomes 10. Pan-genomics of multi drug-resistant human pathogenic bacteria and their resistome 11. Pan-genomics of Virus and its applications 12. Pan-genomics of Fungi and its applications 13. Pan-genomics of Algae and applications 14. Pan-genomics of Plants and its applications 15. Pan-cancer analysis and applications 16. Reverse vaccinology and drug target identification through Pan-genomics 17. Pan-metagenomics and its applications 18. Pan-transcriptomics and its applications 19. Pan-proteomics and its applications 20. Pan-metabolomics and its applications 21. Pan-interactomics and its applications

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Barh, Debmalya
M.Sc. (Applied Genetics), M.Tech. (Biotechnology), M.Phil. (Biotechnology), Ph.D. (Biotechnology), Ph.D. (Bioinformatics), Post-Doc (Bioinformatics), PGDM, is honorary Principal Scientist at Institute of Integrative Omics and Applied Biotechnology (IIOAB), India- a virtual global platform of multidicipliary research and advocacy. He is blended with both academic and industrial research and has more than 12 yrs bioinformatics and personalized diagnostic/ medicine Industry experience where his main focus is to translate academic research into high value commercial products for common mans' reach. He has published more than 150 articles in reputed international journals and has edited 15 cutting-edge omics related reference books published by Taylor& Francis, Springer, Elsevier etc. He has also co-authored 30+ book chapters. Dr. Barh also frequently reviewes articles for Nature publications, Elsevier, BMC Series, PLoS One etc like international Journals. Due to his significant contribution in the field; he has been recognized by Who's Who in the World and Limca Book of Records.
Soares, Siomar C.
Dr Soares holds a degree in Biomedicine, with special training in Bioinformatics, Master's Degree and PhD in Genetics by Federal University of Minas Gerais - UFMG, the latter with one year of study at the Center for Biotechnology (CeBiTec), Universität Bielefeld. He holds a Post-doctorate in Bioinformatics by UFMG. He was Senior Researcher Bioinformatics at the Central Official Laboratory of the Brazilian Ministry of Fisheries and Aquaculture (2014-2015). He is currently Professor at Federal University of the Triângulo Mineiro (UFTM) since 2015, Secretary of the Southeastern regional of the Brazilian Society of Genetics (2017-current), Substitute Coordinator of the undergraduate course in Biomedicine at UFTM (2017-current) and Substitute Research and Technology Development Coordinator of UFTM (2017-current). His research interests are molecular genetics, genomic sequencing and comparative genomics of microorganisms, focusing on pan-genomics, genomic plasticity in the identification of islands of pathogenicity and virulence factors, phylogenomics, molecular epidemiology, reverse vaccination and software development.
Tiwari, Sandeep
Sandeep Tiwari works at the Instituto de Ciencias Biologicas, Universidade Federal de Minas Gerais in Belo Horizonte, Minas Gerais, Brazil.
Azevedo, Vasco
Vasco Azevedo is graduated from veterinary school of the Federal University of Bahia in 1986. He obtained his Master (1989) and Ph.D. (1993) degrees in microbial genetics from Institut National Agronomique Paris-Grignon (INAPG) and Institut National de la Recherche Agronomique (INRA), France, respectively. He did his Post-doctoral research (1994) at Department of Microbiology, School of Medicine, University of Pennsylvania. USA. Since 1995, he is a Professor at Federal University of Minas Gerais (UFMG), Brazil. In 2004, Prof. Azevedo won the Livre-docência contest at the University of São Paulo, which is considered the best university in Brazil. Livre-docência is a degree awarded by the Higher Education Department of Brazil through a public examination open only to the doctoral degree holders and is a recognition to a superior quality of teaching and research. In 2017, Prof. Azevedo defended his third thesis to become a Doctorate in Bioinformatics from the UFMG. He is a also a Fellow of Brazilian Academy of Sciences. He has published 380 research articles, 3 books, and 29 book chapters. Prof. Azevedo is expert in bacterial genetics, genomics, transcriptome, proteomics, and development of new vaccines and diagnostics against infectious diseases. He is pioneer in genetics of Lactic Acid Bacteria and Corynebacterium pseudotuberculosis in Brazil.
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