Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors

Table of Contents

1. Fluorescence microscopy methods for the study of protein oligomerization Roberto Arturo Petazzi, Amit Koikkarah Aji and Salvatore Chiantia 2. Computational prediction and redesign of aberrant protein oligomerization Jaime Santos, Valent?n Iglesias and Salvador Ventura 3. Porphobilinogen synthase: An equilibrium of different assemblies in human health Eileen K. Jaffe 4. Prediction and targeting of GPCR oligomer interfaces Carlos A.V. Barreto, Salete J. Baptista, Ant?nio Jos? Preto, Pedro Matos-Filipe, Joana Mour?o, Rita Melo and Irina Moreira 5. Integrated structural modeling and super-resolution imaging resolve GPCR oligomers Francesca Fanelli, Aylin C. Hanyaloglu and Kim Jonas 6. Exploring functional consequences of GPCR oligomerization requires a different lens Kyla Bourque, Jace Jones-Tabah, Dominic Devost, Paul B.S. Clarke and Terence E. H?bert 7. Continuing challenges in targeting oligomeric GPCR-based drugs Joaquin Botta, Julia Appelhans and Peter J. McCormick 8. Adenosine A2A-dopamine D2 receptor-receptor interaction in neurons and astrocytes: Evidence and perspectives Diego Guidolin, Manuela Marcoli, Cinzia Tortorella, Guido Maura and L. Francesco Agnati 9. Genetic variants in dopamine receptors influence on heterodimerization in the context of antipsychotic drug action Faron-G?recka Agata, Kusmider Maciej, Solich Joanna, G?recki Andrzej and Dziedzicka-Wasylewska Marta 10. Oligomerization of G protein-coupled receptors: Still doubted? Sergi Ferr?, Francisco Ciruela, Vicent Casad? and Leonardo Pardo