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Kidney Transplantation - Principles and Practice. Edition No. 8

  • Book
  • December 2019
  • Elsevier Health Science
  • ID: 4806701
Offering practical guidance for all members of the transplant team, Kidney Transplantation, Principles and Practice, 8th Edition, provides the balanced, up-to-date information you need to achieve optimal outcomes for your patients. A global team of internationally renowned surgeons and nephrologists, many new to this edition, offers fresh perspectives on everything from applied science and surgical techniques to immunosuppressive methods, outcomes, risks, and medical considerations related to kidney transplantation, in both adults and children.

- Offers state-of-the-art coverage of all areas of kidney transplantation such as preservation of kidneys; mechanisms of rejection and the induction of tolerance; techniques of laparoscopic live donor nephrectomy; and immunosuppression.

- Contains up-to-date outcomes data and analysis of the evidence supporting current practice in the field.

- Includes new information on desensitization and considerable new data on the clinical use of costimulation blockade.

- Keeps you current with new chapters on kidney allocation policy that reflects the ethical and societal values of different countries and populations; and biomarkers of kidney injury and rejection, including the need for better monitoring tools to guide therapy and patient management.

- Covers hot topics such as management of chronic allograft failure, the sensitized patient and antibody-mediated rejection, and paired exchange principles.

- Features hundreds of superb illustrations to help you visualize key concepts and nuances of renal transplantation.

- Provides dynamic visual guidance with new real-time video coverage of ultrasound-guided pancreas allograft biopsy; a new animation of calcineurin inhibitor mechanism of action animation; and videos that demonstrate the formation of an immune synapse, 3-D rotational images of immune synapses, an NK cell killing its target, peritoneal dialysis-catheter insertion techniques, laparoendoscopic single site (LESS) donor nephrectomy, and more. - Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices

Table of Contents

Kidney Transplantation - Principles and Practice, 8e

1. Kidney Transplant: A History

2. The Immunology of Transplantation

3. Chronic Kidney Failure: Renal Replacement Therapy

4. The Recipient of A Renal Transplant

5. Access for Renal Replacement Therapy

6. Brain Death and Cardiac Death: Donor Criteria and Care of Deceased Donor

7. Medical Evaluation of the Living Donor

8. Donor Nephrectomy

9. Kidney Preservation

10. Histocompatability in Kidney Transplantation

11. Surgical Techniques of Kidney Transplantation

12. Transplantation and the Abnormal Bladder

13. Perioperative Care of Patients Undergoing Kidney Transplantation

14. Early Course of the Patient with a Kidney Transplant

15. Azathioprine and Mycophenolates

16. Steroids

17. Calcineurin Inhibitors

18. mTor Inhibitors: Sirolimus & Everolimus

19. Antilymphocyte Globulin, Monoclonal Antibodies, and Fusion Proteins

20. Other Forms of Immunosuppression

21. Approaches to the Induction of Tolerance

22. Transplantation in the Sensitized Recipient & Across ABO Blood Groups

23. Paired Exchange Programs for Living Donors

24. Kidney allocation

25. Pathology of Kidney Transplantation

26. Biomarkers in Kidney Injury and Rejection

27. Chronic Allograft Failure

28. Vascular and Lymphatic Complications after Kidney Transplantation

29. Urological Complications after Kidney Transplantation

30. Cardiovascular Disease in Renal Transplantation

31. Infection in Kidney Transplant Recipients

32. Liver Disease among Renal Transplant Recipients

33. Neurological Complications after Kidney Transplantation

34. Cutaneous Disease in Kidney Transplantation Patients

35. Cancer in Dialysis and Transplant Patients

36. Pancreas & Kidney Transplantation for Diabetic Nephropathy

37. Kidney Transplantation in Children

38. Kidney Transplantation in Developing Countries

39. Results of Renal Transplantation

40. Psychological Aspects of Kidney Transplantation and Living Kidney Donation

41. Ethical and Legal Aspects of Kidney Donation

42. Evidence in Transplantation


Stuart J. Knechtle William R. Kenan, Jr. Professor of Surgery; Executive Director, Duke Transplant Center, Adjunct Professor, Department of Medicine, Duke University School of Medicine, Durham, North Carolina. Stuart Knechtle, M.D. is the William R. Kenan, Jr. Professor of Surgery and Executive Director of the Duke Transplant Center. He trained in surgery at Duke and in transplant surgery at the University of Wisconsin, Madison where he was appointed as the first Ray D. Owen Professor of Transplantation. He moved to Emory University in 2008 as the Carlos and Marguerite Mason Professor of Liver Transplantation. In 2015 he returned to Duke to establish the Duke Transplant Center and serve as its Executive Director. He holds the William R. Kenan, Jr. Chair in Surgery at Duke. His clinical practice includes kidney, pancreas, and liver transplantation. He directs translational research in transplant immunology and currently serves as Principal Investigator of two NIH-funded clinical trials addressing the challenges of antibody-mediated injury of kidney transplants. He has published over 400 peer reviewed papers, over 60 book chapters, edited four textbooks, and serves on several editorial boards including Annals of Surgery. Lorna P. Marson Senior Lecturer in Transplant Surgery, University of Edinburgh; Honorary Consultant Transplant Surgeon, Royal Infirmary of Edinburgh. Lorna Marson is Professor of Transplant Surgery at the University of Edinburgh, and Honorary Consultant Surgeon at the Royal Infirmary of Edinburgh. Lorna held a Clinician Scientist Award from the Academy of Medical Sciences/ Health Foundation from 2003-2008, and continues to work in clinically relevant research in renal transplantation, with translation of a novel agent from bench to bedside. Lorna is Past President of the British Transplantation Society, elected Board member of the European Kidney Transplant Association, and Co-Director of the UK Organ Donation and Transplantation Research Network. She is Associate Medical Director for Research and Development, Organ and Tissues Donation and Transplantation, NHS Blood and Transplant. Peter Morris Emeritus Nuffield Professor of Surgery, University of Oxford; Honorary Professor, University of London; Director, Centre for Evidence in Transplantation, Royal College of Surgeons of England; London, UK.