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Organ-on-a-Chip: Global Markets

  • ID: 4807360
  • Report
  • July 2019
  • Region: Global
  • 134 Pages
  • BCC Research
1 of 5

FEATURED COMPANIES

  • 4Dcell
  • Bioivt
  • CN Bio
  • Fluigent
  • Insphero
  • Micronit
  • MORE

Report Scope:

The scope of this report is broad and covers various types of products available in the organ-on-a-chip market and potential application sectors in various industries. The organ-on-a-chip market is broken down by product into instruments and consumables. Revenue forecasts from 2018 to 2023 are given for each product, application, cell type, and end-user, with an estimated value derived from the revenues of manufacturers. Revenue generated from the installation and maintenance of instruments has been excluded from the report.

This report also includes a discussion of the major players in each regional organ-on-a-chip market. Further, it explains the major drivers and regional dynamics of the global market and current trends within the industry.

The report concludes with a special focus on the vendor landscape and includes detailed profiles of the major players in the global organ-on-a-chip market.

The Report Includes:

  • 56 data tables and 49 additional tables
  • An overview of the global market for organ-on-a-chip within the industry
  • Analyses of global market trends, with data from 2017 and 2018, and projections of compound annual growth rates (CAGRs) through 2023
  • Description of potential applications in pharmaceutical and life science research sectors, including preclinical drugs testing, drug screening, personalized medicine, phenotypic screening, lead optimization, and disease modeling
  • Information on multi-channel 3-D microfluidic cell culture chip and discussion of their ability to imitate human microenvironment in vitro
  • Discussion on how organ on a chip is emerging as a priority testing alternative which is replacing animals in life science research, toxicology testing and drug development studies
  • Knowledge about the implementation of 3rs (replacement, refinement, and reduction of animals-based research) in the industry
  • Insights into government programs and policies in support of organ-on-chip and coverage of revised laws involving animal testing
  • Company profiles of the top players in the industry, including Emulate, Hurel Corp., Insphero, Organovo and Synvivo
Note: Product cover images may vary from those shown
2 of 5

FEATURED COMPANIES

  • 4Dcell
  • Bioivt
  • CN Bio
  • Fluigent
  • Insphero
  • Micronit
  • MORE

Chapter 1 Introduction

  • Study Goals and Objectives
  • Reasons for Doing This Study
  • Scope of Report
  • Information Sources
  • Methodology
  • Geographic Breakdown
  • Analyst's Credentials
  • Custom Research
  • Related Reports

Chapter 2 Summary and Highlights

Chapter 3 Market and Technology Background

  • Introduction
  • Developments in Drug Discovery
  • 1950-1970
  • 1970-1990
  • 1990-2010
  • 2010 to the Present
  • Market Potential
  • Investment Analysis
  • Regulatory Framework
  • United States
  • European Union
  • China
  • Japan
  • Industry Growth Drivers
  • Rising Demand to Enhance the Effectiveness of Clinical Trials
  • Increasing Investments for Drug Research and Development
  • Increasing Adoption of Organ-on-a-Chip in Multiple Applications
  • Surging Demand for Lung-Based Organ Cultures in Clinical Studies

Chapter 4 Global Organ-on-a-Chip Market by Type

  • Liver
  • Liver on a Chip Classification Depending on Their Principal Actions
  • Heart
  • Kidney
  • Lung
  • Other Organs

Chapter 5 Global Organ-on-a-Chip Market by End User

  • Biotechnology and Pharmaceutical Companies
  • Cosmetics Industry
  • Academic and Research Institutes
  • Increasing R&D Spending
  • Other End Users

Chapter 6 Global Organ-on-a-Chip Market by Offering

  • Products
  • Services

Chapter 7 Global Organ-on-a-Chip Market by Application

  • Drug Discovery and Development
  • Toxicological Research
  • Physiological Model Development

Chapter 8 Global Organ-on-a-Chip Market by Region

  • North America
  • United States
  • Canada
  • Europe
  • United Kingdom
  • France
  • Germany
  • Spain
  • Rest of Europe
  • Asia-Pacific
  • China
  • Japan
  • India
  • Australia
  • Rest of Asia-Pacific
  • Rest of the World
  • Latin America
  • Middle East and Africa

Chapter 9 Organ-on-a-Chip Industry Structure

  • Raw Material Suppliers
  • Quality and Technology
  • Terms and Conditions
  • Cost-Effective Components
  • Manufacturers
  • Distributors
  • End Users of Consumables
  • Innovation Within the Industry
  • Competitive Analysis

Chapter 10 Company Profiles

  • 4Dcell
  • Axosim
  • Beonchip
  • Biomimx
  • Bioivt
  • Cherry Biotech
  • CN Bio
  • Elveflow
  • Emulate, Inc.
  • Fluigent
  • Hesperos, Inc.
  • Hurel Corp.
  • Insphero
  • Kirkstall
  • Micronit
  • Mesobio Tech
  • Mimetas
  • Nortis
  • Organovo
  • Synvivo
  • Tara Biosystems, Inc.
  • Tissuse Gmbh

List of Tables
Summary Table: Global Organ-on-a-Chip Market, by Type, Through 2023
Table 1: Drug Development Time Span
Table 2: Advantages of Organ-on-a-Chip Compared to Traditional Methods of Drug Discovery
Table 3: U.S. NIH Funding for Various Disease Conditions, 2014-2019
Table 4: Number of Animals Used for Clinical Research, by Country, 2016-2017
Table 5: Global Organ-on-a-Chip Market, by Type, Through 2023
Table 6: Liver-on-a-Chip Classifications
Table 7: Global Liver Organ-on-a-Chip Market, by Region, Through 2023
Table 8: Global Heart Organ-on-a-Chip Market, by Region, Through 2023
Table 9: Deaths from CVD and Number of People Living with CVD in United Kingdom, 2016
Table 10: Global Kidney Organ-on-a-Chip Market, by Region, Through 2023
Table 11: Global Burden of Chronic Kidney Disease, 1990 and 2016
Table 12: Global Lung Organ-on-a-Chip Market, by Region, Through 2023
Table 13: Mortality Rates Due to Leading Respiratory Causes, 2008-2030
Table 14: Global Other Organ-on-a-Chip Market, by Region, Through 2023
Table 15: Global Organ-on-a-Chip Market, by End User, Through 2023
Table 16: Global Biotechnology and Pharmaceutical Company Revenues from the Organ-on-a-Chip Market, by Region, Through 2023
Table 17: U.S. Pharmaceutical R&D Spending, 2005-2015
Table 18: R&D Spending, by India’s Six Largest Pharma Companies, 2016
Table 19: Global Cosmetics Industry Revenues from the Organ-on-a-Chip Market, by Region, Through 2023
Table 20: Global Academic and Research Institution Revenues from the Organ-on-a-Chip Market, by Region, Through 2023
Table 21: Current Grants, by Cancer Type, 2018
Table 22: Global Prevalence of Dementia, 2015-2050
Table 23: Global Other End Users of Organ-on-a-Chip Market, by Region, Through 2023
Table 24: Global Organ-on-a-Chip Market, by Offering, Through 2023
Table 25: Global Organ-on-a-Chip Products Market, by Region, Through 2023
Table 26: Global Organ-on-a-Chip Services Market, by Region, Through 2023
Table 27: Global Organ-on-a-Chip Market, by Application, Through 2023
Table 28: Global Pharmaceutical Market, 2015 and 2020
Table 29: Pharmaceutical Spending as a Percentage of Total Healthcare Spending, by Country, 2016
Table 30: Global Organ-on-a-Chip Market in Drug Discovery and Development, by Region, Through 2023
Table 31: Global Pharmaceutical R&D Spending, by Year, 2015-2022
Table 32: Member Companies of the Pharmaceutical Research and Manufacturers’ R&D Investment in the U.S., 2010-2016
Table 33: Global Organ-on-a-Chip Market in Toxicological Research, by Region, Through 2023
Table 34: Global Organ-on-a-Chip Market in Physiological Model Development, by Region, Through 2023
Table 35: Global Prevalence of Cancer, by Type, 2016
Table 36: Global Organ-on-a-Chip Market, by Region, Through 2023
Table 37: North American Organ-on-a-Chip Market, by Product, Through 2023
Table 38: North American Organ-on-a-Chip Market, by Application, Through 2023
Table 39: North American Organ-on-a-Chip Market, by End User, Through 2023
Table 40: North American Organ-on-a-Chip Market, by Offering, Through 2023
Table 41: NIH Spending on Stem Cell Research in the U.S., by Year, 2013-2016
Table 42: Shares of the Annual Budget of the Canadian Institutes of Health Research, by Type of Research, 2016
Table 43: European Organ-on-a-Chip Market, by Type, Through 2023
Table 44: European Organ-on-a-Chip Market, by End User, Through 2023
Table 45: European Organ-on-a-Chip Market, by Offering, Through 2023
Table 46: European Organ-on-a-Chip Market, by Application, Through 2023
Table 47: Government Funding for Drug-Related Research in France, 2010-2016
Table 48: Rising Prevalence of Cancer Cases in Spain, 2012 and 2015
Table 49: Percentage of Hospitals and Research Centers Participating in Clinical Trials on Cancer, 2004-2016
Table 50: Rising Prevalence of Breast Cancer Cases in Norway, 2014-2015
Table 51: Asia-Pacific Organ-on-a-Chip Market, by Type, Through 2023
Table 52: Asia-Pacific Organ-on-a-Chip Market, by Offering, Through 2023
Table 53: Asia-Pacific Organ-on-a-Chip Market, by End User, Through 2023
Table 54: Asia-Pacific Organ-on-a-Chip Market, by Application, Through 2023
Table 55: Growth in Japanese Pharmaceutical Industry, 2010-2015
Table 56: R&D Spending, by Top Six Pharmaceutical Companies in India, 2018
Table 57: Overall R&D Expenditures in Rest of the World, 2017
Table 58: Rest of the World Organ-on-a-Chip Market, by Application, Through 2023
Table 59: Rest of the World Organ-on-a-Chip Market, by Offering, Through 2023
Table 60: Rest of the World Organ-on-a-Chip Market, by End User, Through 2023
Table 61: Rest of the World Organ-on-a-Chip Market, by Type, Through 2023
Table 62: Capital Raised by Israeli High-Tech Companies, 2013-2017
Table 63: Raw Material/Part Manufacturers
Table 64: Manufacturers Operating in the Organ-on-a-Chip Market
Table 65: End Users of Consumables Operating in the Organ-on-a-Chip Market
Table 66: Shares of Competitive Strategies Used in the Global Organ-on-a-chip Market, 2015-2018
Table 67: 4Dcell: Product Portfolio
Table 68: AxoSim, Inc.: Product Portfolio
Table 69: AxoSim, Inc.: Recent Developments, 2016-2019
Table 70: BEOnChip: Product Portfolio
Table 71: BEOnChip: Recent Developments, 2016-2018
Table 72: BiomimX: Product Portfolio
Table 73: BioIVT: Product Portfolio
Table 74: BioIVT: Recent Developments, 2016-2018
Table 75: Cherry Biotech: Product Portfolio
Table 76: CN Bio: Product Portfolio
Table 77: CN Bio: Recent Developments, 2016-2018
Table 78: Elveflow: Product Portfolio
Table 79: Elveflow: Recent Developments, 2016-2018
Table 80: Emulate, Inc.: Product Portfolio
Table 81: Emulate, Inc.: Recent Developments, 2016-2018
Table 82: Fluigent: Product Portfolio
Table 83: Fluigent: Recent Developments, 2016-2018
Table 84: Hesperos, Inc.: Product Portfolio
Table 85: Hesperos, Inc.: Recent Developments, 2016-2018
Table 86: Hurel Corp.: Product Portfolio
Table 87: Hurel Corp.: Recent Developments, 2016-2018
Table 88: InSphero: Product Portfolio
Table 89: InSphero: Recent Developments, 2016-2018
Table 90: Kirkstall Ltd.: Product Portfolio
Table 91: Micronit: Product Portfolio
Table 92: Micronit: Recent Developments, 2016-2018
Table 93: MesoBio Tech: Product Portfolio
Table 94: Mimetas B.V.: Product Portfolio
Table 95: Mimetas B.V.: Recent Developments, 2016-2019
Table 96: Nortis: Product Portfolio
Table 97: Organovo: Product Portfolio
Table 98: Organovo: Recent Developments, 2016-2018
Table 99: SynVivo: Product Portfolio
Table 100: SynVivo: Recent Developments, 2016-2018
Table 101: Tara Biosystems, Inc.: Product Portfolio
Table 102: Tara Biosystems, Inc.: Recent Developments, 2016-2019
Table 103: Tissuse GmbH: Product Portfolio
Table 104: Tissuse GmbH: Recent Developments, 2016-2018

List of Figures
Summary Figure: Global Organ-on-a-Chip Market, by Type, 2017-2023
Figure 1: Development of Organ-on-a-Chip
Figure 2: Drug Research Cycle
Figure 3: FDA Stages of New Medicine Review and Regulation
Figure 4: Research and Development Process of a Drug
Figure 5: Comparison of the Pipelines of Priority R&D Projects of the Top 20 Companies, by Disease Type, 2018
Figure 6: Global Pharmaceutical R&D Spending, 2015-2022
Figure 7: U.S. NSF Funding for Biological Science Research Studies, 2017
Figure 8: Global Tissue Engineering and Cell Therapy Market Growth, 2009-2018
Figure 9: Major Applications of Organ-on-a-Chip
Figure 10: Global Projections for Deaths from the Top Three Chronic Diseases, 2005-2030
Figure 11: Share of Heart Disease Deaths in the U.S., by Disease, 2017
Figure 12: Organ-on-a-Chip Market End Users
Figure 13: Major Factors Driving the Growth of the Organ-on-a-Chip Market
Figure 14: U.S. Pharmaceutical R&D Spending, 2005-2015
Figure 15: R&D Spending, by India’s Six Largest Pharma Companies, 2016
Figure 16: Shares of Global R&D Funding, by Region, 2018
Figure 17: Top 10 Countries’ R&D Expenditures in Drug Discovery and the Life Sciences, 2016-2018
Figure 18: Global Prevalence of Dementia, 2015-2050
Figure 19: Key Products: Organ-on-a-Chip
Figure 20: Global Pharmaceutical Market, 2015 and 2020
Figure 21: Pharmaceutical Spending as a Percentage of Total Healthcare Spending, by Country, 2016
Figure 22: Global Pharmaceutical R&D Spending, by Year, 2015-2022
Figure 23: Member Companies of Pharmaceutical Research and Manufacturers’ R&D Investment in the U.S., 2010 and 2016
Figure 24: Global Prevalence of Cancer, by Type, 2016
Figure 25: NIH Spending on Stem Cell Research in the U.S., by Year, 2013-2016
Figure 26: Shares of the Annual Budget of the Canadian Institute of Health Research, by Type of Research, 2016
Figure 27: Government Funding for Drug-Related Research in France, 2010-2016
Figure 28: Rising Prevalence of Cancer Cases in Spain, 2012 and 2015
Figure 29: Growth in Japanese Pharmaceutical Industry, 2010-2015
Figure 30: R&D Spending, by the Top Six Pharmaceutical Companies in India, 2018
Figure 31: Overall R&D Expenditures in Rest of the World, 2016-2017
Figure 32: Capital Raised by Israeli High-Tech Companies, 2013-2017
Figure 33: Industry Structure of Instruments Used in the Organ-on-a-Chip Market
Figure 34: Shares of Competitive Strategies Used in the Global Organ-on-a-chip Market, 2015-2018

Note: Product cover images may vary from those shown
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4 of 5

FEATURED COMPANIES

  • 4Dcell
  • Bioivt
  • CN Bio
  • Fluigent
  • Insphero
  • Micronit
  • MORE

An organ-on-a-chip is a type of artificial organ that possesses the capability to simulate activities, mechanics and physiological response similar to that of an organ system. These are multi-channel 3-D microfluidic cell culture chips that are primarily being used in life science and drug development research because of their ability to imitate human microenvironments in vitro. The unique characteristics of organ-on-a-chip are worked out by integrating biology and advanced engineering. Cell biology, microfluidics, and microfabrication are core fields paving their way towards the development of organ-on-a-chip.

Organ-on-a-chip is seen as a priority testing alternative replacing animals in life science research, toxicology testing and drug development studies around the globe. The European Union parliament is looking forward to revising laws involving animal testing. Through groups such as the European Partnership for Alternative Approaches to Animal Testing (EPAA) and International Council of Animal Protection in OECD Programmes (ICAPO), the parliament is seeking to implement policies circumventing 3R (refinement, reduction, and replacement) practices in biomedical research, according to the National Centre for the Replacement Refinement & Reduction of Animals in Research. The Federation of American Societies for Experimental Biology (FASEB), the largest coalition of biomedical research in the U.S. has made organ-on-a-chip a priority investment for research and development for the next five years. Through organ-on-a-chip, FASEB is looking forward to improved productivity in research.

Note: Product cover images may vary from those shown
5 of 5
  • 4Dcell
  • Axosim
  • Beonchip
  • Bioivt
  • Biomimx
  • Cherry Biotech
  • CN Bio
  • Elveflow
  • Emulate, Inc.
  • Fluigent
  • Hesperos, Inc.
  • Hurel Corp.
  • Insphero
  • Kirkstall
  • Mesobio Tech
  • Micronit
  • Mimetas
  • Nortis
  • Organovo
  • Synvivo
  • Tara Biosystems, Inc.
  • Tissuse Gmbh
Note: Product cover images may vary from those shown
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