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B-Cell Non-Hodgkin's Lymphoma: Epidemiology Forecast to 2027

  • ID: 4807488
  • Report
  • June 2019
  • Region: Global
  • 44 pages
  • GlobalData
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B-Cell Non-Hodgkin’s Lymphoma: Epidemiology Forecast to 2027

Summary
Non-Hodgkin’s lymphoma (NHL) refers to a group of cancers that develop in the lymphatic system. In NHL, the patient’s immune system is affected by the uncontrollable growth of malignant white blood cells, resulting in the body’s inability to fight infections and other diseases. NHL accounts for 90% of all malignant lymphomas. NHL is one of the most prevalent hematologic cancers in adults and is more commonly diagnosed in developed countries. B-cell lymphomas are the most common form of NHL diagnosed in developed countries, making up approximately 80-85% of NHL cases in the US.

The burden of diagnosed B-cell non-Hodgkin’s lymphoma (NHL) is expected to increase at an annual growth rate (AGR) of 1.87% from around 154,000 cases in 2017 to 183,000 cases in 2027 in the seven major markets (The US, France, Germany, Italy, Spain, the UK and Japan). In the 7MM, diffuse large B-cell lymphoma (DLBCL) was the most common subtype of B-cell NHL, followed by follicular lymphoma (FL), marginal zone lymphoma (MZL) and mantle cell lymphoma (MCL).

DLBCL is the most common subtype of B-cell NHL. This is important as it is the more aggressive form of cancer with poor prognosis and the risk of mortality from DLBCL will increase in the elderly population with other co-existing diseases and conditions; making it an important patient population to focus on.

In the 7MM, the majority of diagnosed incident cases of DLBCL were in stage IV and the fewest were in stage III in 2017. It is worrying that most cases of DLBCL were diagnosed in the advanced stages as survival will be poor and patients would have required aggressive therapy to get the cancer under control. There is a need for diagnostic tools to detect aggressive cancer such as DLBCL at earlier stages and treatment priorities should also be aligned to address the aggressive form of cancer.

The latest report, 'B-Cell Non-Hodgkin’s Lymphoma: Epidemiology Forecast to 2027', provides an overview of the risk factors and global trends B-Cell Non-Hodgkin's Lymphoma in the seven major markets (7MM: US, France, Germany, Italy, Spain, UK, and Japan).

This report also includes a 10-year epidemiological forecast for the following segmentations in ages 18 years and older across the 7MM: diagnosed incident cases of B-cell NHL; diagnosed prevalent cases of B-cell NHL; and diagnosed incident and prevalent cases of B-cell NHL types such as Diffuse Large B-Cell Lymphoma (DLBCL), Follicular Lymphoma (FL), Marginal Zone Lymphoma (MZL), and Mantle Cell Lymphoma (MCL) in these markets. Additionally, diagnosed incident cases of DLBCL, FL, MZL, and MCL are segmented according to Ann Arbor staging (stage I -IV). Diagnosed incident cases of FL based on grade (Grades 1-3) is also provided in this report.

Scope
  • The B-cell Non-Hodgkin's Lymphoma (B-cell NHL) Epidemiology Report provides an overview of the risk factors and global trends B-Cell Non-Hodgkin's Lymphoma in the seven major markets (7MM: US, France, Germany, Italy, Spain, UK, and Japan).
  • This report also includes a 10-year epidemiological forecast for the following segmentations in ages 18 years and older across the 7MM: diagnosed incident cases of B-cell NHL; diagnosed prevalent cases of B-cell NHL; and diagnosed incident and prevalent cases of B-cell NHL types such as Diffuse Large B-Cell Lymphoma (DLBCL), Follicular Lymphoma (FL), Marginal Zone Lymphoma (MZL), and Mantle Cell Lymphoma (MCL) in these markets. Additionally, diagnosed incident cases of DLBCL, FL, MZL, and MCL are segmented according to Ann Arbor staging (stage I -IV). Diagnosed incident cases of FL based on grade (Grades 1-3) is also provided in this report.
  • The B-cell NHL epidemiology report is written and developed by Masters- and PhD-level epidemiologists.
  • The Epidemiology Report is in-depth, high quality, transparent and market-driven, providing expert analysis of disease trends in the 7MM.
Reasons to buy
The B-cell NHL Epidemiology report will allow you to:
  • Develop business strategies by understanding the trends shaping and driving the global B-cell NHL market.
  • Quantify patient populations in the global B-cell NHL market to improve product design, pricing, and launch plans.
  • Organize sales and marketing efforts by identifying the age groups and sex that present the best opportunities for B-cell NHL therapeutics in each of the markets covered.
  • Understand magnitude of B-cell NHL market by subtypes such as DLBCL, FL, MZL, and MCL.
Note: Product cover images may vary from those shown
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1 Table of Contents
1.1 List of Tables
1.2 List of Figures

2 B-Cell NHL: Executive Summary
2.1 Related Reports
2.2 Upcoming Reports

3 Epidemiology
3.1 Disease Background
3.2 Risk Factors and Comorbidities
3.3 Global and Historical Trends
3.3.1 US
3.3.2 5EU
3.3.3 Japan
3.4 Forecast Methodology
3.4.1 Sources
3.4.2 Forecast Assumptions and Methods
3.5 Epidemiological Forecast for B-Cell NHL (2017-2027)
3.5.1 Diagnosed Incident Cases of B-Cell NHL
3.5.2 Age-Specific Diagnosed Incident Cases of B-Cell NHL
3.5.3 Sex-Specific Diagnosed Incident Cases of B-Cell NHL
3.5.4 Diagnosed Incident Cases of DLBCL, FL, MZL, and MCL
3.5.5 Diagnosed Incident Cases of DLBCL by Cancer Staging
3.5.6 Diagnosed Incident Cases of FL by Cancer Staging
3.5.7 Diagnosed Incident Cases of MZL by Cancer Staging
3.5.8 Diagnosed Incident Cases of MCL by Cancer Staging
3.5.9 Diagnosed Incident Cases of FL by Grade
3.5.10 Diagnosed Prevalent Cases of B-Cell NHL
3.5.11 Diagnosed Prevalent Cases of DLBCL, FL, MZL, and MCL
3.6 Discussion
3.6.1 Epidemiological Forecast Insight
3.6.2 Limitations of the Analysis
3.6.3 Strengths of the Analysis

4 Appendix
4.1 Bibliography
4.2 About the Authors
4.2.1 Epidemiologist
4.2.2 Reviewers
4.2.3 Global Director of Therapy Analysis and Epidemiology
4.2.4 Global Head and EVP of Healthcare Operations and Strategy
4.3 About the author
4.4 Contact Us
4.5 Disclaimer

1.1 List of Tables
Table 1: B-Cell NHL Cancer Stages
Table 2: Risk Factors and Comorbidities for NHL

1.2 List of Figures
Figure 1: 7MM, Diagnosed Incident Cases of B-Cell NHL, Both Sexes, Ages ≥18 Years, 2017 and 2027
Figure 2: 7MM, Age-Standardized Diagnosed Incidence of B-Cell NHL, Ages ≥18 Years, 2017
Figure 3: 7MM, Age-Standardized Diagnosed Prevalence of B-Cell NHL, Ages ≥18 Years, 2017
Figure 4: Sources Used for Diagnosed Incident Cases of B-Cell NHL
Figure 5: Sources Used for Diagnosed Incident Cases of DLBCL, FL, MZL, and MCL
Figure 6: Sources Used for Diagnosed Incident Cases of DLBCL, FL, MZL, and MCL by Cancer Staging
Figure 7: Sources Used for Diagnosed Incident Cases of FL by Grade
Figure 8: Sources Used for Diagnosed Prevalent Cases of B-Cell NHL
Figure 9: Sources Used for Diagnosed Prevalent Cases of DLBCL, FL, MZL, and MCL
Figure 10: 7MM, Diagnosed Incident Cases of B-Cell NHL, Men and Women, Ages ≥18 Years, 2017
Figure 11: 7MM, Age-Specific Diagnosed Incident Cases of B-Cell NHL, Men and Women, 2017
Figure 12: 7MM, Sex-Specific Diagnosed Incident Cases of B-Cell NHL, Men and Women, Ages ≥18 Years, 2017
Figure 13: 7MM, Diagnosed Incident Cases of DLBCL, FL, MZL, and MCL, Men and Women, Ages ≥18 Years, 2017
Figure 14: 7MM, Diagnosed Incident Cases of DLBCL by Cancer Stage, Men and Women, Ages ≥18 Years, 2017
Figure 15: 7MM, Diagnosed Incident Cases of FL by Cancer Stage, Men and Women, Ages ≥18 Years, 2017
Figure 16: 7MM, Diagnosed Incident Cases of MZL by Cancer Stage, Men and Women, Ages ≥18 Years, 2017
Figure 17: 7MM, Diagnosed Incident Cases of MCL by Cancer Stage, Men and Women, Ages ≥18 Years, 2017
Figure 18: 7MM, Diagnosed Incident Cases of FL by Grade, Men and Women, Ages ≥18 Years, 2017
Figure 19: 7MM, Diagnosed Prevalent Cases of B-Cell NHL, Men and Women, ≥18 Years, 2017
Figure 20: 7MM, Diagnosed Prevalent Cases of DLBCL, FL, MZL, and MCL, Men and Women, Ages ≥18 Years, 2017
Note: Product cover images may vary from those shown
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