Chronic Refractory Cough (CRC) - Epidemiology Forecast to 2028

‘Chronic Refractory Cough (CRC)- Epidemiology Forecast to 2028’ report delivers an in-depth understanding of the disease, historical & forecasted epidemiology in the United States, EU5 (Germany, Spain, Italy, France and United Kingdom), and Japan.

Geography Covered

• The United States
• EU5 (Germany, France, Italy, Spain, and the United Kingdom)
• Japan

Chronic Refractory Cough (CRC) - Epidemiology
Chronic refractory cough (CRC) is defined as a cough lasting more than 8 weeks that persists despite guidelines based treatment which may be treated by different medical specialties: Pulmonology, Allergy, and Immunology, Digestive Health and Otorhinolaryngology. CRC is typically nonproductive and there is often a preceding history of viral respiratory tract infection. Patients frequently describe a dry, irritating cough which may be localized to the laryngeal region. Chronic cough lasts more than 8 weeks and can be caused by gastroesophageal reflux disease (GERD), postnasal drip from sinus infections or allergies, or chronic lung conditions, such as asthma, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, and interstitial lung diseases.

The Chronic Refractory Cough Epidemiology report gives the thorough understanding of the Chronic Refractory Cough by including details such as disease introduction, signs and symptoms, causes, risk factors, mechanism of Chronic cough, pathophysiology, the similarity between Chronic Refractory Cough and other neuropathic disorder diagnoses, pathogenesis, clinical features of CRC and diagnosis provides insights about historical and current patient pool and forecasted trend for every seven major countries. The epidemiology data for Chronic Refractory Cough are studied through all possible division to give a better understanding of the disease scenario in the 7MM. It also helps to recognize the causes of current and forecasted trends by exploring numerous studies, research papers, and views of key opinion leaders.

Chronic Refractory Cough (CRC) Epidemiology
In the United States, cough is the most common complaint for which patients seek medical attention and is the second most common reason for a general medical examination, accounting for more than 26 million office visits annually. Cough often results from an acute, self-limited, viral upper respiratory tract infection; however, there are multiple causes of cough beyond this, including both respiratory tract and nonrespiratory tract-related etiologies. Cough that lasts more than 8 weeks is considered to be chronic as per defined by the American College of Chest Physicians (ACCP). The cough becomes chronic if it persists, often due to an underlying etiology that is difficult to diagnose or treat.

The disease epidemiology covered in the report provides historical as well as forecasted epidemiology scenario of Chronic Refractory Cough in the 7MM covering the United States, EU5 countries (Germany, Spain, Italy, France, and the United Kingdom) and Japan from 2017 to 2028 for the following aspects:

• Prevalent Population of Chronic Cough
• Gender-wise Prevalent Population of Chronic Cough
• Prevalent Population of Chronic Refractory Cough
• Diagnosed Prevalent Population of Chronic Refractory Cough
• Diagnosed Prevalent Population of Chronic Refractory Cough in Idiopathic Pulmonary Fibrosis (IPF) patients

According to a study conducted by Jun et al. titled “Effect of pregabalin for the treatment of chronic refractory cough,” which stated that nearly 11–16% of patients suffer from chronic refractory cough during their life. Although many patients had received satisfactory treatment, there were still 20–40% of patients who suffered long-term cough symptoms even after standardized treatment. The study was concluded stating that an innovative treatment with fewer adverse effects and long-term relief was necessary for CRC patients.

According to a study conducted by Weinberger et al. titled “Long-lasting cough in an adult German population: incidence, symptoms, and related pathogens” researchers assessed the burden of suffering related to prolonged coughing and tried to identify further causative agents. It was found that incidence of pertussis in adults have shown that it accounted for only approximately 5–15% cases of prolonged coughing in which, symptoms were not indicative of a specific agent and a total of 64% of patients received antibiotics. The study was concluded by stating that prolonged adult coughing required medical attention, which prompted substantial healthcare use.

Report Scope

• The report covers a detailed overview of Chronic Refractory Cough explaining its causes, symptoms, and classification, pathophysiology, and diagnosis and treatment patterns.
• The report provides the insight about the historical and forecasted patient pool for seven major markets covering the United States, EU5 (Germany, Spain, France, Italy, UK), and Japan.
• The report assesses the disease risk and burden and highlights the unmet needs of Chronic Refractory Cough
• The report helps to recognize the growth opportunities in the 7MM with respect to the patient population.

Key Strengths

• 10 Year Forecast of Chronic Refractory Cough epidemiology
• 7MM Coverage
• Total Prevalent Cases of Chronic Refractory Cough
• Prevalent Cases according to the segmentation

Key Assessments

• Patient Segmentation
• Disease Risk & Burden
• Risk of disease by the segmentation
• Factors driving growth in a specific patient population