The Europe early toxicity testing market accounted for $265 million in 2017, and is expected to reach $460 million by 2025, registering a CAGR of 7.1% from 2018 to 2025.
Toxicity is the degree of threat posed by a substance to the living organism, and toxicology is a branch of science that deals with measurement and further analysis of these chemical substances and their adverse effects on the body of an organism. The effects of chemical substances on the body are studied to choose a potential drug candidate during the development of newer molecules. Early toxicity testing is carried out at preclinical stages of a drug development process and is essential as toxicity serves as the major reason for the failure of potential drug candidates in the later stages of drug development leading to huge financial loss to companies. Moreover, companies perform early toxicity testing to comply with the government standards to market the drug. Early toxicity testing can be performed using different techniques such as in vivo, in vitro, and in silico. These techniques are employed to carry out different toxicity tests such as ocular toxicity, carcinogenicity, systemic toxicity, and others.
Major factors that drive the market growth are surge in the research and development activities and increase in stringency of regulatory authorities concerning public healthcare welfare. In addition, technological advancements in vitro techniques, rise in adoption of in vitro models in the Europe early toxicity testing industry and surge in adoption of early toxicity testing further boost the market growth. However, limitations associated with preclinical testing hamper the market growth. Furthermore, the technological advancements related to early toxicity testing provide lucrative opportunities for the market growth during the forecast period.
This report segments the Europe early toxicity testing market on the basis of technique, application, end users, and country to provide a detailed assessment of the market. Based on technique, the market is divided into in vivo, in vitro, and in silico. The market on the basis of in vitro is further divided into in vitro toxicity testing market by assays and in vitro toxicity testing market by toxicity endpoints. The in vitro toxicity testing market by assays is further segmented into enzyme toxicity assays, bacterial toxicity assays, cell-based ELISA & western blots, receptor binding assays, and other assays. The in vitro toxicity testing market by toxicity endpoints is further divided into dermal toxicity, systemic toxicity, carcinogenicity, ocular toxicity, skin sensitization and irritation, neurotoxicity, organ toxicity, and other toxicity endpoints. Based on country, the market is studied across different countries of Europe such as Germany, France, the UK, and rest of Europe.
KEY BENEFITS FOR STAKEHOLDERS
KEY MARKET SEGMENTS
o In Vitro
In Vitro Toxicity Testing Market by Assays
o Chemical testing
o Others
o Food Industry
o Chemicals Industry
o Cosmetics Industry
o Other Industries
o France
o UK
o Rest of Europe
LIST OF KEY PLAYERS PROFILED IN THE REPORT (DEVICE PROVIDERS)
LIST OF OTHER PLAYERS IN THE VALUE CHAIN (These players are not profiled in the report. The same will be included on request)
Major factors that drive the market growth are surge in the research and development activities and increase in stringency of regulatory authorities concerning public healthcare welfare. In addition, technological advancements in vitro techniques, rise in adoption of in vitro models in the Europe early toxicity testing industry and surge in adoption of early toxicity testing further boost the market growth. However, limitations associated with preclinical testing hamper the market growth. Furthermore, the technological advancements related to early toxicity testing provide lucrative opportunities for the market growth during the forecast period.
This report segments the Europe early toxicity testing market on the basis of technique, application, end users, and country to provide a detailed assessment of the market. Based on technique, the market is divided into in vivo, in vitro, and in silico. The market on the basis of in vitro is further divided into in vitro toxicity testing market by assays and in vitro toxicity testing market by toxicity endpoints. The in vitro toxicity testing market by assays is further segmented into enzyme toxicity assays, bacterial toxicity assays, cell-based ELISA & western blots, receptor binding assays, and other assays. The in vitro toxicity testing market by toxicity endpoints is further divided into dermal toxicity, systemic toxicity, carcinogenicity, ocular toxicity, skin sensitization and irritation, neurotoxicity, organ toxicity, and other toxicity endpoints. Based on country, the market is studied across different countries of Europe such as Germany, France, the UK, and rest of Europe.
KEY BENEFITS FOR STAKEHOLDERS
- The study provides an in-depth analysis of the Europe early toxicity testing market along with the current trends and future estimations to elucidate the imminent investment pockets.
- A quantitative analysis from 2017 to 2025 is discussed to enable the stakeholders to capitalize on the prevailing market opportunities.
- In-depth analysis of early toxicity testing techniques such as in vivo, in vitro, and in silico is carried out in the report.
- The profiles and growth strategies of the key players are thoroughly analyzed to understand the competitive outlook of the European market.
KEY MARKET SEGMENTS
- By Technique
o In Vitro
In Vitro Toxicity Testing Market by Assays
- Enzyme Toxicity Assays
- Bacterial Toxicity Assays
- Cell-Based ELISA and Western Blots
- Tissue Culture Assays
- Receptor Binding Assays
- Other Assays
- Dermal Toxicity
- Systemic Toxicity
- Carcinogenicity
- Ocular Toxicity
- Skin Sensitization and Irritation
- Genotoxicity
- Neurotoxicity
- Organ Toxicity
- Other Toxicity Endpoints
- By Application
o Chemical testing
o Others
- By End User
o Food Industry
o Chemicals Industry
o Cosmetics Industry
o Other Industries
- By Country
o France
o UK
o Rest of Europe
LIST OF KEY PLAYERS PROFILED IN THE REPORT (DEVICE PROVIDERS)
- Agilent Technologies, Inc.
- General Electric Company (GE Healthcare)
- Danaher Corporation (Beckman Coulter, Inc.)
- Evotec AG (Cyprotex)
- Bioanalytical Systems, Inc.
- Bruker Corporation
- Thermo Fisher Scientific, Inc.
- PerkinElmer Inc.
- Enzo Biochem, Inc. (Enzo Clinical Labs, Inc.)
- The Jackson Laboratory
LIST OF OTHER PLAYERS IN THE VALUE CHAIN (These players are not profiled in the report. The same will be included on request)
- Randox Toxicology
- Geneva Laboratories, Inc.
- Advanced Chemistry Development (ACD/Labs)
Table of Contents
CHAPTER 1: INTRODUCTION
Chapter 2: EXECUTIVE SUMMARY
Chapter 3: MARKET OVERVIEW
Chapter 4: EUROPE EARLY TOXICITY TESTING MARKET, BY TECHNIQUE
Chapter 5: EUROPE EARLY TOXICITY TESTING MARKET, BY APPLICATION
Chapter 6: EUROPE EARLY TOXICITY TESTING MARKET, BY END USER
Chapter 7: EUROPE EARLY TOXICITY TESTING MARKET, BY COUNTRY
Chapter 8: COMPANY PROFILES, KEY MANUFACTURERS
Executive Summary
According to this report titled 'Europe Early Toxicity Testing Market by Technique, Application and End User: Opportunity Analysis and Industry Forecast, 2018 - 2025', the Europe early toxicity testing market is expected to reach $460 million by 2025, registering a CAGR of 7.1% from 2018 to 2025, in terms of value.Early toxicity testing is the analysis of a new drug compound in the drug development process. The testing is conducted to determine the damage caused to the body by the compound. Toxicity testing of drugs is vital as it helps in avoiding severe adverse drug reactions in the body. The testing is carried out in different mediums such as in vivo, in vitro, and in silico. These tests are carried out before pre-clinical trials to analyze the drug candidates, which are further tested in clinical studies carried out in humans. Moreover, early toxicology testing is necessary as it can prevent financial losses that occur during the failure of drugs in further late stages of drug development.
Factors that drive the growth of the Europe early toxicity testing market include rise in R&D activities and surge in stringent regulatory authorities concerning public healthcare welfare. In addition, increase in adoption of in vitro model due to strict guidelines in favor of animal protection also serves as factors for the growth of market. However, challenges of preclinical testing hamper the market growth. Furthermore, technological advancements in preclinical procedures provide lucrative opportunities for the market growth.
On the basis of technique, in vitro segment is major revenue contributor in 2017 and is expected to maintain its dominant position throughout the analysis period due to rise in adoption of this technique across different diagnostic areas. Europe is extensively active toward protection of animals. Europe government has banned testing of cosmetic and household products on animals. Therefore, in vitro testing serves as a feasible alternative to in vivo testing, which serves as another major reason for the growth of the in vitro market. Moreover, lower costs associated with carrying out this technique also boost the growth of this market. In silico segment is the fastest growing segment during the forecast period, owing to rise in its adoption due to advantages offered by the technique. In silico techniques have revolutionized the drug discovery process as these techniques are not only applied to find new targets and new molecule with high affinity to those targets but also used to determine the metabolic pathways of those active molecules. In addition, these techniques are computer-based that eliminate animal sacrifice, which is another factor that fuels the growth of this market.
Based on application the Europe early toxicity testing market is segmented into drug discovery, chemical testing and others. According to end users, pharmaceutical segment is expected to be the fastest growing segment throughout the forecast period. It also accounted for the highest share in 2017, and is anticipated to maintain this trend over the forecast period, owing to rise in number of clinical trials for drug development. During drug development, early toxicity testing can help reduce the risk of later stage failure for drug development, which predominantly fuel the growth of the pharmaceutical industry market.
In 2017, Germany accounted approximately one fifth share of the total Europe early toxicity testing market and is expected to continue this trend owing to higher number of R&D activities, high presence of research lab, companies and institutes, and wide availability of technologically advanced preclinical diagnostic instruments. On the other side the UK is estimated to register the fastest growth during the forecast period.
Key Findings of the Europe Early Toxicity Testing Market:
Germany occupied approximately one fifth share of the Europe early toxicity testing market in 2017.
The in silico segment is anticipated to grow with the highest CAGR throughout the forecast period.
The pharmaceutical industry segment accounted for more than two third share of the market in 2017.
The cosmetic industry is anticipated to grow at the highest rate during the analysis period.
The major companies profiled in this report include Agilent Technologies, Inc., General Electric Company (GE Healthcare), Danaher Corporation (Beckman Coulter, Inc.), Evotec AG (Cyprotex), Bioanalytical Systems, Inc., Bruker Corporation, Thermo Fisher Scientific, Inc., PerkinElmer Inc., Enzo Biochem, Inc. (Enzo Clinical Labs, Inc.), The Jackson Laboratory.
Methodology
The analyst offers exhaustive research and analysis based on a wide variety of factual inputs, which largely include interviews with industry participants, reliable statistics, and regional intelligence. The in-house industry experts play an instrumental role in designing analytic tools and models, tailored to the requirements of a particular industry segment. The primary research efforts include reaching out participants through mail, tele-conversations, referrals, professional networks, and face-to-face interactions.
They are also in professional corporate relations with various companies that allow them greater flexibility for reaching out to industry participants and commentators for interviews and discussions.
They also refer to a broad array of industry sources for their secondary research, which typically include; however, not limited to:
- Company SEC filings, annual reports, company websites, broker & financial reports, and investor presentations for competitive scenario and shape of the industry
- Scientific and technical writings for product information and related preemptions
- Regional government and statistical databases for macro analysis
- Authentic news articles and other related releases for market evaluation
- Internal and external proprietary databases, key market indicators, and relevant press releases for market estimates and forecast
Furthermore, the accuracy of the data will be analyzed and validated by conducting additional primaries with various industry experts and KOLs. They also provide robust post-sales support to clients.
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