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US Fecal Microbiome Transplant Market Outlook 2025

  • ID: 4843064
  • Report
  • September 2019
  • Region: United States
  • 75 Pages
  • Kuick Research
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until Jun 30th 2020
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FEATURED COMPANIES

  • Finch Therapeutics
  • Maat Pharma
  • OpenBiome
  • Rebiotix
  • Seres Therapeutics
  • Vedanta Bioscience
  • MORE

"US Fecal Microbiome Transplant Market Outlook 2025" Report Highlights:

  • US Fecal Microbiota Transplant Market Scenario
  • US Fecal Microbiota Transplant Market Opportunity: > US$ 150 Million by 2025
  • Number of Fecal Microbiota Transplant Market in US: >20000 by 2025
  • US To Dominate Global Fecal Microbiota Transplant Market: > 50% Market Share
  • Fecal Microbiota Transplant vs. Antibiotic Therapy

The human microbiota has a major and vital role in the well-being of the human host and contributes actively to the occurrence of a wide variety of diseases. Microorganisms have extensive influence throughout the human body and hence research on the Microbiota modifying methods, such as Fecal Microbiota Transplant, are under investigation. Currently, the US is emerging as a global leader in Fecal Microbiota Transplant market. The number of procedures of Fecal Microbiota Transplant is increasing continuously in the US and it will continue to follow the same trajectory in future driven by increasing awareness and high regulatory approvals. In 2018, the US Fecal Microbiota Transplant market was less than US$ 100 Million and is expected to double its size by 2025.

The strong clinical pipeline of Fecal Microbiota Transplant is acting as a major driving force for the exponential growth of US Fecal Microbiota Transplant market. There are more than 250 trials under investigation from which about 36 trials are under Phase III and phase IV of clinical development. The trials are related to different diseases such as metabolic disorders, cardiovascular disorders, psychiatric disorders, and cancer also. This will indicate a bright future of Fecal Microbiota Transplant market and continuous growth will take place in future years.

Fecal Microbiota Transplant is currently approved only for the management of C. difficile infection. As the Prevalence rate of C. difficile infection is increasing day by day, the number of Fecal Microbiota Transplant procedures will increase continuously. High efficacy of Fecal Microbiota Transplant as compared to the standard antibiotic therapy is also acting as a major driving force, which will promote the Fecal Microbiota Transplant market. The approval of Fecal Microbiota Transplant for management of inflammatory bowel disease will also take place within a year, which further enhances the number of Fecal Microbiota Transplant procedures in future and all this leads to the rapid growth of Fecal Microbiota Transplant market.

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FEATURED COMPANIES

  • Finch Therapeutics
  • Maat Pharma
  • OpenBiome
  • Rebiotix
  • Seres Therapeutics
  • Vedanta Bioscience
  • MORE

1. What is Fecal Microbiome Transplant (FMT)
1.1 Overview
1.2 History of FMT

2. Need of Fecal Microbiota Transplantation
2.1 Therapeutic Needs
2.2 Supplementary Needs
2.3 Need for Disease Prevention

3. Clinical Trial Related To Fecal Microbiota Transplant
3.1 Clinical Trial for Recurrent C. Difficile
3.2 Clinical Trial for Inflammatory Bowel Disease (IBD)
3.3 Other FMT Related Clinical Trials

4. US - Fecal Microbiota Transplant Market Scenario
4.1 Overview
4.2 Current Market Scenario

5. Fecal Microbiota Transplant Price Analysis
5.1 FMT Preparation Formats - Availability & Cost Analysis
5.2 Additional Expenditures

6. FMT vs. Antibiotic Therapy
6.1 Efficacy Comparison
6.2 Cost Effectiveness of Antibiotic Therapeutics vs. FMT

7. US - Fecal Microbiota Transplant Market Drivers

8. Challenges for US Fecal Microbiota Transplant Market

9. US - Fecal Microbiota Transplant Market Future Outlook

10. Competitive Landscape
10.1 OpenBiome
10.2 Maat Pharma
10.3 Finch Therapeutics
10.4 Rebiotix
10.5 Seres Therapeutics
10.6 Vedanta Bioscience

List of Figures
Figure 1-1: Procedure of Fecal Microbiota Transplantation (FMT)
Figure 1-2: Approaches for Microbiome Therapeutics
Figure 1-3: Types of Microbiota Transplant
Figure 1-4: Microbiome Composition of Healthy Human Gut
Figure 1-5: Historical Development of Fecal Transplantation (300AD-1950AD)
Figure 1-6: Historical Development of FMT (After 1950)
Figure 2-1: Needs of Fecal Microbiota Transplant
Figure 2-2: Disorders with Positive Effect of FMT
Figure 3-1: Number of Clinical Trial Studies Related to Fecal Microbiota Transplant in Different Phases, 2019
Figure 3-2: Fecal Microbiota Transplant in Different Phases of Clinical Trial (%), 2019
Figure 3-3: Status of Active FMT Clinical Trials
Figure 3-4: FMT Clinical Trial in Management of C. Difficile Infection, 2019
Figure 3-5: FMT Clinical Trial in Management of Inflammatory Bowel Disease, 2019
Figure 4-1: US – Total C. Difficile Patients vs. FMT Eligible C. Difficile Patients, 2019
Figure 4-2: US - Antibiotic Responsive vs. Non-Responsive C. Fifficile Patients (%), 2019
Figure 4-3: Probability of 1st, 2nd, & 3rd Episode of C. Difficile Infection Reoccurrence (%), 2019
Figure 4-4: US – Number of FMT Treatments Shipped by OpenBiome, 2014 - 2019
Figure 4-5: Global Microbiome Therapeutic Market Size  (US$ Million), 2018 - 2025
Figure 4-6: Microbiome Therapeutic Market Size – Global vs. US (US$ Million), 2018
Figure 4-7: Global Microbiome Therapeutic Market Share (%) – US, Europe & Rest of World, 2018 & 2025
Figure 4-8: US – Number of FMT Procedures, 2018 - 2025
Figure 4-9: US – FMT Market Size (US$ Million), 2018 - 2025
Figure 5-1: Components of Total Cost for Fecal Microbiota
Figure 5-2: US - Fecal Microbiota Transplant Preparation Formats Available in Market
Figure 5-3: US – Price of OpenBiome’s Upper, Lower and Oral Delivery FMT Preparation (US$), September’2019
Figure 5-4: US – Cost of 30 Capsules & per Unit Price of OpenBiome FMT (US$), September’2019
Figure 5-5: Additional Expenditure Associated with Fecal Microbiome Transplantation
Figure 5-6: US – Average Cost of Colonoscopy, Sigmoidoscopy & Endoscopy Procedures (US$), 2018
Figure 5-7: US – Average Stay Charges/ Day in Local Government, Non-Profit & Profitable Hospital (US$), 2016
Figure 6-1: Standard Antibiotics for Management of C. Difficile Infection
Figure 6-2: Patient Cure Efficacy of FMT (Colonoscopy) & Oral Vancomycin against Recurrent CDI (%)
Figure 6-3: Patient Cure Efficacy of FMT (Nasogastric), Oral Vancomycin & Vancomycin + Bowel Lavage against Recurrent CDI (%)
Figure 6-4: Treatment Duration of Vancomycin, Metronidazole & Fidaxomycine for CDI (Days)
Figure 6-5: Daily Unit Dose of Vancomycin, Metronidazole & Fidaxomycine Orally for CDI
Figure 6-6: Vancomycin – Price for Single Capsule of 250mg, 20 Capsule Supply & Full Treatment Cost vs. Oral FMT Cost (US$), September’2019
Figure 6-7: Vancomycin – Price for Single Dose of 500mg & Full Treatment Cost vs. Oral FMT Cost (US$), September’2019
Figure 6-8: Metronidazole - Price for Single Dose of 500mg & Full Treatment Cost vs. Oral FMT Cost (US$), September’2019
Figure 6-9: Metronidazole - Price for Single Dose of 250mg & Full Treatment Cost vs. Oral FMT Cost (US$), September’2019
Figure 6-10: Metronidazole – Price for Single Dose of 500mg/100ml IV Solution, 2400 ml Supply & Full Treatment cost vs. Oral FMT Cost (US$), September’2019
Figure 6-11: Fedaxomycin - Price for Single Dose of 200mg & Full Treatment Cost vs. Oral FMT Cost (US$), September’2019
Figure 7-1: US – Fecal Microbiota Transplant Market Drivers
Figure 8-1: Challenges for US Fecal Microbiota Transplant Market

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  • Finch Therapeutics
  • Maat Pharma
  • OpenBiome
  • Rebiotix
  • Seres Therapeutics
  • Vedanta Bioscience
Note: Product cover images may vary from those shown
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