The global market for viral vector and plasmid DNA technologies is expected to grow from USD 2.9 Billion in 2023 to USD 7.1 Billion by the end of 2028, at a compound annual growth rate (CAGR) of 19.70% from 2023 through 2028.
Report Scope
The report provides a comprehensive summary of the viral vector and plasmid DNA technologies market focusing cell and gene therapies, along with detailed competitive landscape and profiles of key market players that include revenue, product portfolios and recent activities. The report analyzes trends and dynamics, including drivers, limitations, challenges, and opportunities. This research study discusses historical, current, and potential market size. The report will enable market players and new entrants to make informed decisions about the production and licensing of goods and services. Organizations, distributors, and exporters should find the information about market development and trends useful. The study segments the market on the basis of product type, applications, and end use. Geographical market analysis is provided for all the major segments. The report offers country-level analysis of markets to provide a better understanding of the major segments.
The market is divided into segments and by application/industry as follows
By product type
- Viral vector
- Plasmid DNA
By application
- Cancer
- Genetic disorders
- Infectious diseases
- Cardiovascular diseases.
- Other diseases
By end-user
- Research institutes
- Pharmaceutical and biopharmaceutical companies
Each area is covered in detail, identifying current products in the market in the base year (2022), measuring the current market size and identifying current and potential market drivers, forecasting for 2028, assessing current and potential competitors, and identifying current competitor market shares for 2022.
Report Includes
- 93 data tables and 47 additional tables
- An overview of the global market for viral vector and plasmid DNA
- Analyses of global market trends, with data from 2020-2022, estimates for 2023, and projections of compound annual growth rates (CAGRs) through 2028
- Evaluation of the current market size and revenue growth prospects for viral vector and plasmid DNA, along with a market share analysis by product type, application and geographic region
- A look at the innovations, technological advances, and product launches from leading companies
- Analysis of the industry’s regulatory framework and policies, and its product pipeline
- Discussion of ESG challenges and ESG practices
- Analysis of the key companies’ market shares, proprietary technologies, strategic alliances and other market strategies, and patents
- Profiles of the leading players in the industry
Table of Contents
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Executive Summary
Viral vectors are viruses developed through cultured DNA recombination techniques. This modification makes the viruses ideal for delivering genetic material into target cells or tissues for therapeutic purposes. Types of viral vectors include adenoviruses, retroviruses, poxviruses, adeno-associated viruses (AAV), and herpes simplex viruses (HSVs). Delivery of foreign DNA using viral vectors has flaws, particularly when attempts are made to apply the technology to gene therapy. However, as researchers learn more about viral vectors and their impact on human immune response, advancements in safe and effective viral-based treatments continue. Meanwhile, the refinement of viral-mediated gene delivery protocols proceeds, providing a convenient, flexible, and reproducible system for in vitro transfection studies. Plasmid DNA vaccines offer speed, simplicity, and breadth of immune response by overcoming the issues regarding effectiveness and safety of therapy during treatment. Innovative plasmid DNA vaccines can be useful for the immunization of humans against infectious diseases and cancers.
The global viral vector and plasmid DNA technologies market’s projected growth stems from factors such as the rising prevalence of various diseases such as cancer, infectious diseases, and other genetic disorders, the growing trend toward gene therapy owing to their promising clinical results, and increasing partnerships and collaborations between companies and research institutes in gene therapy.
The rising incidence and prevalence rate of cancer is considered a key factor in the growth of the global viral vector and plasmid DNA technologies market. According to the WHO (World Health Organization), cancer is the second-leading cause of mortality in the world, responsible for 9.6 million deaths and accounting for 18.1 million new cases in 2018. Consequently, there is significant demand for cancer therapeutics based on innovative technologies such as viral vectors and plasmid DNA. Viral vectors are being researched for applications in cancer therapies and to support the delivery of genetic information to a tumor, which will permit the development of therapeutic proteins. The process typically involves introducing DNA into a cell (transfection), which encodes for a protein and other important genetic elements needed for the introduction of the gene of interest expression that facilitates successful production of protein. Some approved gene therapies, like Kymriah for acute lymphoblastic leukemia (ALL) and large B cell lymphoma, have induced market players to research and develop gene therapy for cancer treatment. However, regulatory challenges, vector characterization, and QC testing, and manufacturing challenges have restrained growth in the global viral vector and plasmid DNA technologies market.
The global viral vector and plasmid DNA technologies market was segmented based on the product, application, and end-user. Based on the product, the global viral vector and plasmid DNA technologies market further is analyzed into plasmid DNA and viral vectors. The viral vector is the most operative resource of gene transfer to modify specific cell type or tissue and can be manipulated to express therapeutic genes. Various types of viruses include adenoviruses, retroviruses (?-retroviruses and lentiviruses), poxviruses, AAV, baculoviruses, and HSV. These viruses are under investigation as applications to deliver genes to cells for either transient or permanent transgene expression. The rising applications of these viruses should boost the growth of the viral vector in gene therapy.
Companies Mentioned
- Agilent Technologies Inc.
- Bluebird Bio Inc.
- Catalent Inc.
- Danaher Corp.
- Fujifilm Holdings Corp.
- Genscript
- Gilead Sciences Inc.
- Lonza
- Novartis Ag
- Oxford Biomedica Plc
- Plasmidfactory Gmbh
- Regenxbio Inc.
- Thermo Fisher Scientific Inc.
- VGXI Inc
Table Information
Report Attribute | Details |
---|---|
No. of Pages | 128 |
Published | March 2024 |
Forecast Period | 2023 - 2028 |
Estimated Market Value ( USD | $ 2.9 Billion |
Forecasted Market Value ( USD | $ 7.1 Billion |
Compound Annual Growth Rate | 19.7% |
Regions Covered | Global |
No. of Companies Mentioned | 14 |