Risk Factors for Psychosis: Paradigms, Mechanisms, and Prevention combines the related, but disparate research endeavors into a single text that considers all risk factors for psychosis, including biological, psychological and environmental factors. The book also introduces the ethics and current treatment evidence that attempts to ameliorate risk or reduce the number of individuals with risk factors developing a psychotic disorder. Finally, the book highlights new research paradigms that will further enhance the field in the future.
Psychotic disorders affect more than 50 million people worldwide, creating a devastating effect on lives and causing major financial and emotional impact on families and on society as a whole. The search for risk factors for psychosis has developed rapidly over the past decades, invigorated by changes in the thinking about the malleability and treatability of psychotic disorders. The paradigms for investigating psychosis risk have developed, often in parallel, but there has been no book to date that has summarized and synthesized the current approaches.
- Integrates research from biological, psychological and environmental factors into a single resource
- Offers insight into at-risk paradigms, biomarkers, and the current state of research on treatment option for psychosis
- Presents a holistic and dynamic look at risk syndromes and how they can be measured through neuroimaging, neuropsychology and other methods
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1. Historical perspectives on psychosis risk 2. Risk, screening and prevention in psychosis and psychiatry 3. Risk for schizophrenia and the schizophrenia prodrome 4. The At-Risk Mental and Psychosis Risk Syndrome 5. Basic symptoms and self-disturbance 6. Schizotypy and schizotypal personality disorder 7. Genetic high risk and genetic high-risk studies 8. Psychotic-Like Symptoms in the general population 9. Imaging and risk for psychosis 10. Genes and risk 11. Risk and Potential Biomarkers 12. Neurochemical models of risk and onset 13. Clinical factors related to risk 14. Neuropsychological risk factors for psychosis 15. The environment and psychosis risk 16. Ethical issues of identifying and treating psychosis risk 17. Indicated prevention in psychosis risk 18. Population interventions to reduce risk 19. New paradigms to study psychosis risk 20. "At risk for what" - Psychosis risk and Youth Mental Health
Dr Andrew Thompson is a Principal Research Fellow and Associate Professor at Orygen, the Centre for Youth Mental Health at the University of Melbourne, Australia. He is the lead psychiatrist for the EPPIC early psychosis service and the National headspace Early Psychosis program in Australia and is currently head of clinical psychosis research at Orygen. He also retains a position as Associate Professor at the University of Warwick in the UK.
Andrew trained in medicine at the University of Oxford and London and in psychiatry in Nottingham and Bristol. He has an MD in clinical psychiatry from the University of London. He has worked in early psychosis practice and research for over 15 years in both the UK and Australia. He was previously clinical lead for the PACE at risk for psychosis clinic in Melbourne and has been involved in a number of research projects through this clinic and through his work at the University of Bristol and the University of Warwick.
Andrew's research interests include clinical risk factors for the development of psychosis and psychotic symptoms, novel treatments (including technology) in emerging or early psychosis, predictors of outcome in early psychosis and systems of care and prevention approaches in youth mental health.
Dr Matthew Broome is a Senior Clinical Research Fellow at the Department of Psychiatry, University of Oxford, and a Consultant Psychiatrist at the Early Intervention in Psychosis Service, Oxford. He trained in medicine at the University of Birmingham and in Psychiatry at the Maudsley hospital (where he worked at the at risk for psychosis clinic (OASIS). He has previously been a Lecturer at the Institute of Psychiatry and an Associate Clinical Professor at The University of Warwick. He has previously edited books on subjects such as phenomenology and the interface between psychiatry and philosophy and has published over 100 research papers mostly relating to at risk for psychosis groups.