Delivery of Drugs: Expectations and Realities of Multifunctional Drug Delivery Systems, Volume Two examines the formulation of micro-nanosized drug delivery systems and recaps opportunities for using physical methods to improve efficacy via mechano-, electroporation. The book highlights innovative delivery methods like PIPAC, including discussions on the regulatory aspects of complex injectables. Written by a diverse range of international researchers from industry and academia, the chapters examine specific aspects of characterization and manufacturing for pharmaceutical applications as well as regulatory and policy aspects.
This book connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stakeholders. This level of discussion makes it a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about the status of drug delivery systems.
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Table of Contents
1. Polymer lipid hybrid (PLH) formulations: a synergistic approach to oral delivery of challenging therapeuticsPAUL JOYCE, HAYLEY B. SCHULTZ, TAHLIA R. MEOLA, AND CLIVE A. PRESTIDGE
2. Dendrimers for pharmaceutical applicationsdpotential and challenges
J�RN B. CHRISTENSEN
3. Electrospun nanofibers for biomedical applications
FRANCIS KAMAU MWIIRI AND ROLF DANIELS
4. Nanocarriers for topical delivery in psoriasis
GAUTAM SINGHVI, SIDDHANTH HEJMADY, VAMSHI KRISHNA RAPALLI, SUNIL KUMAR DUBEY, AND� SACHIN DUBEY
5. Mitochondria-targeted drug delivery in neurodegenerative diseases
SARAVANA BABU CHIDAMBARAM, BIPUL RAY, ABID BHAT, AREHALLY MARAPPA MAHALAKSHMI, TULADHAR SUNANDA, PADAMATI JAGADEESWARI, MYSORE PRAKASH GOWRAV, RAMESH CHANDRA, AND� MEENA KISHORE SAKHARKAR
6. Nano-structured microparticles for inhalation
ALJOSCHA KOENNEKE, MARCEL POURASGHAR, AND MARC SCHNEIDER
7. Physical approaches for drug delivery: an overview
PALLAVI SHINDE, AMOGH KUMAR, KAVITHA, KOYEL DEY, L. MOHAN, SRABANI KAR, TARUN KUMAR BARIK, JAVAD SHARIFI-RAD, MOETO NAGAI, AND TUHIN SUBHRA SANTRA
8. Complex injectables: development, delivery, and advancement
ABHIJEET PANDEY, DEBJANI SINGH, NAMDEV DHAS, AKHILESH KUMAR TEWARI, KAMLA PATHAK, VIVEKANAND CHATAP, KAMAL SINGH RATHORE, AND SRINIVAS MUTALIK
9. Pressurized intraperitoneal aerosol chemotherapy (PIPAC) in colorectal cancer treatment
XAVIER DELGADILLO AND PHILIPPE WUTHRICH
