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Global Opportunities in Cerebral Embolization Markets

  • ID: 4852641
  • Report
  • October 2019
  • Region: Global
  • 102 pages
  • Life Science Intelligence
1 of 3

FEATURED COMPANIES

  • Acandis
  • BALT
  • J&J Cerenovus
  • Medtronic
  • MicroPort Medical
  • Penumbra
  • MORE
Although the number of cerebral embolization procedures performed globally is fairly limited relative to many other interventions, the associated product sales are impressive: estimated at $1.75 billion globally in 2018, representing roughly $11,300 per procedure. These high outlays - which include not only the specialized coils, liquid embolics, flow diverters and stent-assisted coil devices but also the microcatheters, micro guidewires, access devices, micro-occluding balloons and other devices employed ancillary to them - reflect two major factors.

The first is the specialized “micro” nature of neuro-interventional products, which creates design and quality control challenges for manufacturers. The second is the limited number of procedures, which precludes the production economies of scale necessary to attract new suppliers and support competitive pricing. In essence, neurointerventional products carry premium prices because they are premium products. Even the fairly recent influx of new flow diversion products did not create downward pricing pressure in that segment as expected; rather, pricing increased slightly.

Thus, we have not incorporated an expectation of downward pricing pressure into our forecast for cerebral embolization products as procedure volumes are not expected to reach a critical mass. Nevertheless, product sales are projected to increase at an 8.0% real annual rate through 2023 to $2.58 billion, representing nearly $12,000 per procedure.

Competitors covered in this analysis include:
  • Acandis
  • BALT
  • J&J Cerenovus
  • Medtronic
  • MicroPort Medical
  • Penumbra
  • Phenox
  • Rapidmedical
  • Stryker
  • Terumo MicroVention
  • Others
Note: Product cover images may vary from those shown
2 of 3

FEATURED COMPANIES

  • Acandis
  • BALT
  • J&J Cerenovus
  • Medtronic
  • MicroPort Medical
  • Penumbra
  • MORE
Executive Summary
  • Cerebral Embolization Procedures
  • Embolization Products Market
  • Supplier Shares
Summary Exhibit 1: Global Trend in Subarachnoid Hemmorrhage (SAH), Intact Cerebral Aneurysms (CAs), Arteriovenous Malformations (AVMs) and Associated Embolization Procedures, 2018-2023
Summary Exhibit 2: Trends in SAH/Aneurysm Embolizations and AVM Embolizations, by Major Geography, 2018-2023
Summary Exhibit 3: Global Trend in Cerebral Embolization Products Market, by Major Category, 2018-2023
Summary Exhibit 4: Global Sales of Cerebral Embolization Products, by Major Geography, 2018-2023
Summary Exhibit 5: Global Cerebral Embolization Products, Supplier Shares, 2018

1. Etiology & Epidemiology of Acute Stroke
1.1 Overview of the Brain
1.1.1 Cerebral Arterial Blood Supply
1.2 Etiology of Stroke
1.2.1 Ischemic Stroke
1.2.1.1 Causative Mechanisms
1.2.1.2 Symptoms
1.2.1.3 Risk Factors
1.2.1.4 Diagnosis
1.2.1.5 Treatment
1.2.1.6 Incidence
1.2.2 Hemorrhagic Stroke
1.2.2.1 Intracerebral Hemorrhage
1.2.2.1.1 Symptoms
1.2.2.1.2 Diagnosis and Treatment
1.2.2.2 Subarachnoid Hemorrhage
1.2.2.2.1 Causes and Risk Factors
1.2.2.2.2 Symptoms
1.2.2.2.3 Diagnosis
1.2.2.2.4 Treatment
1.2.2.3 Incidence

Exhibit 1-1: Overview of the Brain
Exhibit 1-2: Arterial Blood Supply to Brain
Exhibit 1-3: Comparison of Ischemic and Hemorrhagic Stroke
Exhibit 1-4: Global Incidence of Ischemic and Hemorrhagic Stroke, 2018-2023
Exhibit 1-5: Incidence of Ischemic and Hemorrhagic Stroke, United States, 2018-2023
Exhibit 1-6: Incidence of Ischemic and Hemorrhagic Stroke, Major Europe, 2018-2023
Exhibit 1-7: Incidence of Ischemic and Hemorrhagic Stroke, Major Asia-Pacific, 2018-2023
Exhibit 1-8: Incidence of Ischemic and Hemorrhagic Stroke, Rest-of-World, 2018-2023
Exhibit 1-9: Comparison of Intracerebral and Subarachnoid Hemorrhage

2. Embolization Approaches to Stroke Management
2.1 Hemorrhagic Stroke Targeted Pathologies
2.1.1 Intracranial Aneurysms
2.1.2 Arteriovenous Malformations (AVMs)
2.2 Management Options
2.2.1 Surgical Repair
2.2.2 Endovascular Embolization
2.2.2.1 Microcoil Systems
2.2.2.2 Liquid Embolic Systems
2.2.2.3 Coil-Containing Stent Systems
2.2.2.4 PVA Particles and Beads
2.2.2.5 Neurovascular Occlusion Balloons
2.2.2.6 Occlusion Meshes
2.2.2.7 Flow Diverting Embolization Systems
2.3 Procedures

Exhibit 2-1: Comparison of Endovascular Approaches & Products for Stroke Management
Exhibit 2-2: Cerebral Aneurysm and Arteriovenous Malformation
Exhibit 2-3: Comparison of Endovascular Approaches & Products for Stroke Management
Exhibit 2-4: Surgical Aneurysm Clipping
Exhibit 2-5: Comparison of Cerebral Embolic Agents and Approaches
Exhibit 2-6: Selected Microcoil Products, 2019
Exhibit 2-7: Selected Coil-Containing Stent Systems, 2019
Exhibit 2-7: Selected Coil-Containing Stent Systems, 2019 (Continued)
Exhibit 2-8: Selected Neurovascular Occluding Balloons, 2019
Exhibit 2-9: Selected Neurovascular Occluding Meshes, 2019
Exhibit 2-10: Results of Selected Clinical Trials of Flow Diversion Embolization Systems
Exhibit 2-11: Selected Flow Diversion Embolization SystemsCoil-Containing Stent Systems, 2019
Exhibit 2-12: Global Endovascular Embolizations for Cerebral Aneurysms, 2018-2023
Exhibit 2-13: United States Endovascular Embolizations for Cerebral Aneurysms, 2018-2023
Exhibit 2-14: Major Europe Endovascular Embolizations for Cerebral Aneurysms, 2018-2023
Exhibit 2-15: Major Asia-Pacific Endovascular Embolizations for Cerebral Aneurysms, 2018-2023
Exhibit 2-16: Rest-of-World Endovascular Embolizations for Cerebral Aneurysms, 2018-2023

3. Product Markets
3.1 Market by Major Segment
3.1.1 Aneurysm Embolics and Associated Devices
3.1.2 AVM Embolics and Associated Devices
3.1.3 Supplier Shares
3.2 Market by Major Geography

Exhibit 3-1: Global Sales of Cerebral Embolization Products, by Major Segment and Geography, 2018-2023
Exhibit 3-2: Global Sales of Aneurysm Embolization Products, by Major Type, 2018-2023
Exhibit 3-3: Global Cerebral Embolization Products, Supplier Shares, 2018
Exhibit 3-4: United States Cerebral Embolization Procedures and Products, by Major Type, 2018-2023
Exhibit 3-5: United States, Cerebral Embolization Products, Supplier Shares, 2018
Exhibit 3-6: Major Europe Cerebral Embolization Procedures and Products, by Major Type, 2018-2023
Exhibit 3-7: Major Europe, Cerebral Embolization Products, Supplier Shares, 2018
Exhibit 3-8: Major Asia Pacific Cerebral Embolization Procedures and Products, by Major Type, 2018-2023
Exhibit 3-9: Major Asia-Pacific, Cerebral Embolization Products, Supplier Shares, 2018
Exhibit 3-10: Rest-of-World Cerebral Embolization Procedures and Products, by Major Type, 2018-2023
Exhibit 3-11: Rest-of-World, Cerebral Embolization Products, Supplier Shares, 2018
Note: Product cover images may vary from those shown
3 of 3
  • Acandis
  • BALT
  • J&J Cerenovus
  • Medtronic
  • MicroPort Medical
  • Penumbra
  • Phenox
  • Rapidmedical
  • Stryker
  • Terumo MicroVention
Note: Product cover images may vary from those shown
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