Companion Diagnostics (CDx) Market - Forecasts from 2022 to 2027

A companion diagnostic device is a medical device that enables the user to receive crucial information regarding the use of corresponding drugs or biological products. The prime reason which is forecasted to drive the market growth is the rising prevalence of chronic diseases which has increased the market adoption of companion diagnostics. Furthermore, increasing healthcare expenditure with the rise in the standard of living and availability of technology coupled with demand for precision medicine has created notable opportunities for the companion diagnostic device.



Based on geography, the companion diagnostics (CDx) market is segmented into North America, South America, Europe, the Middle East and Africa, and the Asia Pacific. The Asia Pacific region is forecasted to hold a substantial share of the market owing to a surge in medical tourism and advancement in the medical sector. The North American and European regions are projected to hold the largest share of the market with an increase in healthcare spending.

A next-generation sequencing companion diagnostic is expected to hold a notable share of the market.

Based on technology, the companion diagnostic market can be distinguished as a polymerase chain reaction, immunohistochemistry, in-situ hybridization, and next-generation sequencing. A next-generation sequencing companion diagnostic is expected to hold a significant share of the market, owing to technological effectiveness and better market prospects.

Lung and Breast Cancer indication is expected to dominate the market for a companion diagnostic.

By indication, the companion diagnostic market can be segmented into lung cancer, breast cancer, colorectal cancer, and others. Lung and breast cancer indication is expected to dominate the companion diagnostic market, owing to a higher number of cases. Lung and breast cancer are the two most prevalent types of cancers. These two are also the form of cancers with the highest number of deaths. A report published by the World Health Organization (WHO) shows that in 2020, there were 2.26 million cases of breast cancer, while 2.21 million cases of lung cancer. Breast cancer caused 685 thousand deaths in 2020, while lung cancer killed 1.80 million people. The growing prevalence of these forms of cancers is expected to create significant demand for a companion diagnostic.

Growth Factors

Rising cases of cancer

One of the prime reasons supporting the growth in the companion diagnostics (CDx) market is the surging cancer cases. Companion diagnostic notably helps in cancer diagnostic and treatment. The device facilitates identifying a specific therapeutic solution for an individual suffering from cancer. A rise in cancer cases is expected to drive notable demand for companion diagnostic devices. Data from National Cancer Institute, NIH shows that 1.806 million new cases of cancer were diagnosed in the United States in 2020, increasing the rate of new cancer cases to 442.4% per 100,000 people. The rise in cancer cases is expected to surge the demand for diagnostic and treatment, hence supporting the market for a companion diagnostic.

The surge in healthcare expenditure

Another key factor that supports the market for companion diagnostics (CDx) is a surge in healthcare expenditure with the rise in the standard of living and the adoption of advanced medical technology. Data from The World Bank shows that global per capita healthcare expenditure has been increasing at a remarkable rate. Per capita healthcare expenditure reached US$1,110.286 in 2018 from US$1,020.88 in 2016. Promising investment in the industry is expected to expand the market prospects further. In the US, for instance, healthcare expenditure is expected to grow at a CAGR from 2019 to 2028 and is expected to reach US$6.2 trillion by 208, from US$4.1 trillion in 2020. It is expected to invest in the healthcare industry and is projected to provide exceptional growth opportunities.

COVID Insights

The coronavirus pandemic resiliently impacted the market for a companion diagnostic. The surge in cases and the emergency situation created by the robust spread of the COVID-19 led to more fund investment towards the vaccination and hence impacted the market for a companion diagnostic. Furthermore, fear of catching the virus refrained patients from going for regular checks, which impacted the discovery of new or potential cases and affected the market prospects.

Key Development

• April 2021, Approval. The FDA gave a green signal to the country’s first-ever companion diagnostic device developed especially for endometrial cancer diagnosis, innovated by Roche. Ltd. The VENTANA MMR RxDx Panel developed by the latter successfully identifies endometrial cancer and helps in its treatment. Annually, around 90 thousand women die due to endometrial cancer. The companion diagnostic developed by Roche can identify the patient’s eligibility for JEMPERLI monotherapy.

Market Segmentation:

By Technology

• Polymerase Chain Reaction (PCR)
• Immunohistochemistry (IHC)
• In-situ Hybridization (ISH)
• Next-Generation Sequencing (NGS)

By Indication

• Lung Cancer
• Breast Cancer
• Colorectal Cancer
• Others

By Geography

• North America
• USA
• Canada
• Mexico
• South America
• Brazil
• Argentina
• Others
• Europe
• Germany
• France
• United Kingdom
• Italy
• Others
• Middle East and Africa
• Saudi Arabia
• Israel
• Others
• Asia Pacific
• China
• India
• Japan
• South Korea
• Others