Handbook of Biomaterials Biocompatibility is a systematic reference on host response to different biomaterials, taking into account their physical, mechanical and chemical properties. The book reviews recent progress in the design and study of biomaterials biocompatibility, along with current understanding on how to control immune system response. Sections provide the fundamental theories and challenges of biomaterials biocompatibility, the role of different biomaterials physicochemical surface properties on cell responses, cell responses to different physicochemical properties of polymers, ceramics, metals, carbons and nanomaterials, and biomaterials in different tissues, such as the cardiac, nervous system, cartilage and bone.
This resource will be suitable for those working in the fields of materials science, regenerative engineering, medicine, medical devices and nanotechnology.
- Reviews the fundamental theories and challenges of biomaterials biocompatibility, including an overview of the standards and regulations
- Provides an overview on the cellular and molecular mechanisms involved in host responses to biomaterials
- Systematically looks at cellular response and tissue response to a wide range of biomaterials, including polymers, metals, ceramics, alloys and nanomaterials
Volume I: An introduction to biocompatibility 1. Biocompatibility Definition and Issues 2. Cell-Biomaterials Interactions 3. Protein Responses to Biomaterials 4. Macrophages Responses to Biomaterials 5. Dendritic Cells Responses to Biomaterials 6. Impact of Biomaterials' Physical Properties on Cellular and Molecular Responses 7. Impact of Biomaterials' Mechanics on Cellular and Molecular Responses 8. Impact of Biomaterials' Chemistry on Cellular and Molecular Responses 9. Cell-Biomaterials Interactions: The Role of Growth Factors 10. Cell-Biomaterials Interactions: The Role of Ligand Functionalization 11. Methods of Testing Cell-Biomaterials Interactions 12. In vivo Models for Biomaterials 13. Clinical impacts of biocompatibility: What surgeons ought to know 14. Standardization and Regulation of Biomaterials
Volume II: Cellular Response to Biomaterials 15. Cellular Response to Natural Polymers 16. Cellular Response to Synthetic Polymers 17. Cellular Response to Composite Polymers 18. Cellular Response to Zirconia 19. Cellular Response to Alumina 20. Cellular Response to Carbon-family materials 21. Cellular Response to Calcium phosphate cements 22. Cellular Response to Bioactive glasses and Glass-Ceramics 23. Cellular Response to Titanium Alloys 24. Cellular Response to Co-Based Alloys 25. Cellular Response to Stainless Steels 26. Cellular Response to Nano-Biomaterials
Volume III: Tissue Response to Biomaterials 27. Central Nervous System Responses to Biomaterials 28. Peripheral Nervous System Responses to Biomaterials 29. Cardiac Responses to Biomaterials 30. Vascular Responses to Biomaterials 31. Bone Responses to Biomaterials 32. Tendon and Muscle Responses to Biomaterials 33. Cartilage Responses to Biomaterials 34. Pulmonary system Responses to Biomaterials 35. Gastrointestinal Organs' Responses to Biomaterials 36. Ocular Responses to Biomaterials 37. Skin Responses to Biomaterials
Dr. Masoud Mozafari is a Fellow at Lunenfeld Tanenbaum Research Institute, Mount Sinai Health Hospital, University of Toronto. He was previously Assistant Professor and Director of the Bioengineering Lab, at the Nanotechnology and Advanced Materials Department, Materials and Energy Research Center, Cellular and Molecular Research Center, and Department of Tissue Engineering and Regenerative Medicine of the Iran University of Medical Sciences (IUMS), Tehran, Iran. Dr. Mozafari's research interests range across biomaterials, nanotechnology, and tissue engineering, and he is known for the development of strategies for the treatment of damaged tissues and organs, and controlling biological substances for targeted delivery into the human body. Dr. Mozafari has received several awards, including the Khwarizmi Award and the Julia Polak European Doctorate Award for outstanding translational research contributions to the field of biomaterials. He has also received the WIPO Medal for Inventors from The World Intellectual Property Organization (WIPO), in recognition of his contributions to economic and technological development. Dr. Mozafari is currently working on the editorial board of several journals.