Handbook of Amygdala Structure and Function, Volume 26, provides an updated overview on the functional neuroanatomy of amygdala nuclei, with an emphasis on interconnections (basolateral, central amygdala, medial amygdala) and their integration into related networks/circuits (prefrontal cortex, bed nucleus, nucleus accumbens). The design of this volume builds upon the foundations of functional neural circuits and the corresponding (cellular) electrophysiology important for the homeostatic control of amygdala function. This volume contains a dedicated section on the anatomical organization of the amygdala nuclei, emphasizing the role of neurotransmitters and neuropeptides that integrate signals and regulate behavior.
Additional chapters discuss cellular physiology, plasticity and the integration of electrical signals that contribute to neural activity. The final section of the book connects the role of amygdala dysfunction and the development of disorders in human health and disease.
- Emphasizes a comparative and multidisciplinary approach on the topic of the amygdala
- Discusses, in detail, the role of amygdala dysfunction and the development of disorders in human health and disease
- Examines the current state of research in cellular physiology, plasticity and the integration of electrical signals
- Includes a dedicated section on neuropeptides, neurotransmitters and cannabinoids that links to behavior control
1. Functional Neuroanatomy of the Basolateral Amygdala: Neurons, Neurotransmitters, and Circuits 2. The Medial Amygdala: Structure and Function 3. Amygdala Neuron Subtypes Based on Genetics, Physiology and Anatomy 4. Amygdala physiology in pain 5. Neural Plasticity of the Amygdala 6. Plasticity of amygdala neurons underlying fear learning and extinction 7. Neuropeptide Y and Amygdala Circuitry: Modulation of Stress Behaviors 8. The Amygdalar Opioid System 9. Noradrenergic Regulation of the Basolateral Amygdala 10. Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) in Stress, Pain, and Learning 11. Protect and Harm
Effects of Stress on the Amygdala 12. Sex Differences in Amygdala Structure and Function: From Rodents to Humans
Dr. Urban graduated from Saint Mary's College, Notre Dame, Indiana with a degree in Biology and Chemistry. She completed her PhD thesis work in the Department of Pharmacology and Experimental Therapeutics at Loyola University Stritch School of Medicine where her work focused on the serotonergic regulation of stress hormone secretion. Afterwards, Janice pursued postdoctoral work in the Department of Pharmacology at the University of Washington in Seattle, WA examining the regulation of neuropeptides in limbic brain regions by gonadal steroids. Dr. Urban continued postdoctoral research in the Department of Neurobiology and Physiology at Northwestern University, and was a member of the Center for Reproductive Sciences at Northwestern University, Evanston, IL prior to joining the faculty in the Department of Physiology and Biophysics at the Chicago Medical School. Dr. Urban has an active research program in the areas of neuroendocrinology and elucidating mechanisms underlying stress resilience. She is active in graduate and medical teaching and is a member of the Society for Neuroscience, American Physiological Society, Endocrine Society and American Neuroendocrine Society. Dr. Urban is currently Professor and Chair of the department of Physiology and Biophysics.
Rosenkranz, J. Amiel
Dr. Rosenkranz graduated from the University of Pittsburgh in 1997. He remained at the University of Pittsburgh to earn the M. S. degree in 1999 and the PhD in 2002, both in Neuroscience. Following postdoctoral work at the Baylor College of Medicine and University of Texas-Austin he joined the faculty of the Department of Cellular and Molecular Pharmacology of the Chicago Medical School in 2007.