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Epigenetic Mechanisms in the Brain

  • Book

  • 350 Pages
  • June 2020
  • Elsevier Science and Technology
  • ID: 4894748

Epigenetic Mechanisms in the Brain provides recent findings in the field of neuroepigenetics, covering how our genes encode our memories, transmit information about stressful events, and play a part in our addictions. This book helps to unlock these abstract processes, with a forward goal of improving individualized treatments.



  • Discusses how the epigenome affects long-term memory, stress and addiction
  • Reviews the concept of transgenerational memory
  • Describes treatment options for the epigenome

Table of Contents

1. What Qualifies as Epigenetic? 2. Lost in the Histone Code 3. The Prima Donna 4. How Neurons Use the Epigenome 5. Epigenetics in a Postmitotic Cell 6. Metaplasticity 7. Our Genes are as Plastic as Our Neurons 8. Long-term Memory formation 9. Stress 10. Addiction 11. Common Features of Regulation Across Epigenetic Marks 12. Transgenerational Memory 13. Inheriting Stress 14. Imprinted Cognitive Effects 15. Inheriting Spatial Cognition 16. Experience May Direct Evolution 17. Forgiving Lamarck 18. Epigenetics Guides Mutations 19. Editing and Drugging the Epigenome 20. Unique Pharmacokinetics 21. Ethical Concerns 22. Rewriting the Epigenome and the Past

Authors

Kennedy, Andrew J. Andrew J. Kennedy is at Bates College, Lewiston, ME, USA. Chua, Gabriella N.L. Gabriella N.L. Chua is a graduate student in the Tri-Institutional PhD Program in Chemical Biology, jointly sponsored by the Weill Cornell Medical College, Memorial Sloan Kettering Cancer Center, and The Rockefeller University.