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Nanotechnology Based Approaches for Tuberculosis Treatment

  • ID: 4894811
  • Book
  • June 2020
  • Region: Global
  • 370 Pages
  • Elsevier Science and Technology
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Nanotechnology Based Approaches for Tuberculosis Treatment discusses multiple nanotechnology-based approaches that may help overcome persisting limitations of conventional and traditional treatments. The book summarizes the types of nano drugs, their synthesis, formulation, characterization and applications, along with the most important administration routes. It also explores recent advances and achievements regarding therapeutic efficacy and provides possible future applications in this field. It will be a useful resource for investigators, pharmaceutical researchers, innovators and scientists working on technology advancements in the areas of targeted therapies, nano scale imaging systems, and diagnostic modalities in tuberculosis.

  • Addresses the gap between nanomedicine late discovery and early development of tuberculosis therapeutics
  • Explores tuberculosis nanomedicine standardization and characterization with newly developed treatment, diagnostic and treatment monitoring modalities
  • Covers the field thoroughly, from the pathogenesis of tuberculosis and multi-drug resistant mycobacterium tuberculosis, to treatment approaches using nanotechnology and different nanocarriers
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1. Tuberculosis: Introduction, drug regimens and multidrug-resistance
2. Pathogenesis and Immunology of tuberculosis
3. Role of essential trace elements in tuberculosis infection
4. Multi-drug resistant mycobacterium tuberculosis & oxidative stress complexity
5. Inhalable polymeric dry powders for anti-tuberculosis drug delivery
6. Nanotechnology based approaches in tuberculosis treatment
7. Liposome and niosmoes based drug delivery systems for tuberculosis treatment
8. Nanoparticle based drug delivery systems for tuberculosis treatment
9. Microemulsions and nanoemulsion-based drug delivery systems for tuberculosis treatment
10. Dendrimer and polymeric micelle based drug delivery systems for tuberculosis treatment
11. Nanostructured lipid carrier based drug delivery systems for tuberculosis treatment
12. DNA markers and nano-biosensing approaches for tuberculosis diagnosis
13. Agility of quantitative proteomics in tuberculosis research
14. Recent advancement and future perspectives for the treatment of multidrug resistant-tuberculosis
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Kesharwani, Prashant
Dr. Prashant Kesharwani is currently working as Assistant Professor, Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India. He received his doctoral degree in Pharmaceutical Sciences from the Dr H.S. Gour University (Sagar, India) with Prof N.K Jain's group. He is a recipient of several internationally acclaimed awards viz "Ramanujan Fellowship, DST, India-2017”, "Excellence Research Award-2014”, "Young Innovator Award (Gold medal)-2012”, "International Travel Award/Grant from DST (New Delhi), and INSA (CCSTDS, Chennai)-2012”. He has received ICMR Senior Research Fellowship (in PhD) and AICTE Junior Research Fellowship (in M. Pharm.). After his doctorate, he worked as postdoctoral fellows in the Wayne State University, Detroit (Michigan, USA). Dr. Kesharwani subsequently joined the School of Pharmacy, International Medical University (Malaysia) as lecturer in Pharmaceutical Technology. Subsequently he joined Central Drug Research Institute (CDRI), Lucknow as Ramanujan Fellow. An overarching goal of his current research is the development of nano-engineered drug delivery systems for cancer through with prime focus on dendrimer and polymeric nanomicelles mediated drug delivery systems. Dr. Kesharwani is a co-author on more than 120 publications in high impact factor international journals and 4 international books with total citations of more than 3300 (h index is 27 and i-10 index is 65 as per Google Scholar).
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