+353-1-416-8900REST OF WORLD
+44-20-3973-8888REST OF WORLD
1-917-300-0470EAST COAST U.S
1-800-526-8630U.S. (TOLL FREE)

PRINTER FRIENDLY

From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors, Vol 88. Advances in Pharmacology

  • ID: 4894863
  • Book
  • June 2020
  • Region: Global
  • 312 Pages
  • Elsevier Science and Technology
1 of 2

From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors, Volume 88, the latest release in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this updated edition include Targeting muscarinic M1 receptor in neurodegeneration, Photo-switchable allosteric ligands, Computational approaches for the design of mGlu receptor allosteric modulators, Allosteric modulation of GLP-1 receptor in metabolic disorders, Group II mGluR roles in the nervous system and their roles in addiction, RAMPs as allosteric modulators of Class B GPCRs, Structure-based discovery and development of mGlu5 NAMs, and much more.

  • Includes the authority and expertise of leading contributors in pharmacology
  • Presents the latest release in the Advances in Pharmacology series
Note: Product cover images may vary from those shown
2 of 2
- The computational modeling of allosteric modulation of metabotropic glutamate receptors

Laura Pérez-Benito, Claudia Llinas del Torrent, Leonardo Pardo and Gary Tresadern

- Structure-based discovery and development of metabotropic glutamate receptor 5 negative allosteric modulators

Kirstie A. Bennett, John A. Christopher and Benjamin G. Tehan

- The function and allosteric control of the human sweet taste receptor

Guy Servant, Terry Kenakin, Lan Zhang, Mark Williams and Nicole Servant

- The different aspects of the GABAB receptor allosteric modulation

Julie Kniazeff

- RAMPs as allosteric modulators of the calcitonin and calcitonin-like class B G protein-coupled receptors

Augen A. Pioszak and Debbie L. Hay

- Strategies and considerations of G-protein-coupled receptor photopharmacology

Alice E. Berizzi and Cyril Goudet

- Discovery and pharmacology of the covalent GLP-1 receptor (GLP-1R) allosteric modulator BETP. A novel tool to probe GLP-1R pharmacology

Francis S. Willard, Joseph D. Ho and Kyle W. Sloop

- Allosteric modulation of metabotropic glutamate receptors in alcohol use disorder: Insights from preclinical investigations

Kari A. Johnson and David M. Lovinger

- Allosteric modulation of muscarinic receptors in alcohol and substance use disorders

Leigh C. Walker and Andrew J. Lawrence

- M1 muscarinic acetylcholine receptors: A therapeutic strategy for symptomatic and disease-modifying effects in Alzheimer's disease?

Miriam Scarpa, Sarah Hesse and Sophie J. Bradley
Note: Product cover images may vary from those shown
3 of 2

Loading
LOADING...

Adroll
adroll