The importance of protein stability for the biological functions is widely recognized. It is the ability of the protein to preserve its function in given conditions over time. Protein stability is the net balance of forces, which determine whether a protein will be its native folded conformation or a denatured (unfolded or extended) state. Hence analysis of protein stability becomes important from research point of view.
The growth of the protein stability analysis market is primarily driven by the growing adoption of open innovation models in pharmaceutical & biotechnology companies and increasing pharmaceutical outsourcing. Emerging economies will provide new growth opportunities for players in the market. However, the high cost of protein stability analysis systems is expected to restrain the growth of this market to a certain extent.
Key Market Trends
Differential Scanning Calorimetry (DSC) is Expected to Register Healthy CAGR Over the Forecast Period
Differential Scanning Calorimetry technique has been widely used in characterizing the stability of proteins in their native form by measuring the amount of heat required to denature a particular biomolecule, like protein. This technique determines molecules with higher thermal transition midpoints as these are considered more stable than those with lower transition midpoints. This technique is widely used in research & development and drug discovery.
The importance of research and development (R&D) for the pharmaceutical industry is evidenced by the cumulative R&D expenditure in the sector. It has been observed that the R&D spending is increasing each year and several pharma and biotech companies are focusing on strengthening their R&D facilities which is ultimately driving the growth of market studied.
As the R&D expenditure increased further, the demand for protein stability analysis techniques like DSC are expected to increase.
North America is Expected to Dominate the Market
North American countries such as the United States (US) and Canada have a developed and well-structured health care system. These systems also encourage research and development and drug discovery efforts. The policies encourage global players to enter the US and Canadian market. As a result, these countries enjoy the presence of many global market players who are involved in R&D. Presence of the key players of market studied increases the demand for protein stability analysis techniques. As a result this region is expected to dominate the market.
Majority of the protein stability analysis instrumnets and techniques are being manufactured by the global key players. Market leaders with more funds for research and better distribution system have established their position in the market. Moreover, Asia-pacific is witnessing an emergence of some small players due to the rise of awareness. This has also helped the market grow.
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1.2 Study Assumptions
1.3 Scope of the Study
4.2 Market Drivers
4.2.1 Growing Adoption of Open Innovation Models in Pharmaceutical and Biotechnology Companies
4.2.2 Increasing Pharmaceutical Outsourcing
4.3 Market Restraints
4.3.1 High Cost of Protein Stability Analysis Instruments
4.4 Porter's Five Force Analysis
4.4.1 Threat of New Entrants
4.4.2 Bargaining Power of Buyers/Consumers
4.4.3 Bargaining Power of Suppliers
4.4.4 Threat of Substitute Products
4.4.5 Intensity of Competitive Rivalry
5.1.1 Reagents and Assay Kits
5.1.3 Consumables and Accessories
5.2 By Technique
5.2.3 Surface Plasmon Resonance
5.2.4 Differential Scanning Calorimetry
5.2.5 Differential Scanning Fluorimetry
5.2.6 Other Techniques
5.3 By End-User
5.3.1 Pharmaceutical & Biotechnology Companies
5.3.2 Academic and Research Organizations
5.4.1 North America
126.96.36.199 United States
188.8.131.52 United Kingdom
184.108.40.206 Rest of Europe
5.4.3 Asia Pacific
220.127.116.11 South Korea
18.104.22.168 Rest of Asia-Pacific
5.4.4 Middle East and Africa
22.214.171.124 South Africa
126.96.36.199 Rest of Middle East and Africa
5.4.5 South America
188.8.131.52 Rest of South America
6.1.1 Agilent Technologies, Inc.
6.1.2 NanoTemper Technologies
6.1.3 Horiba, Ltd
6.1.4 Perkinelmer, Inc.
6.1.5 Setaram Instrumentation
6.1.6 Shimadzu Corporation
6.1.7 Spectris PLC
6.1.8 Thermo Fisher Scientific
6.1.9 Unchained Labs
6.1.10 Danaher Corporation (Molecular Devices LLC-FORTEBIO)
6.1.11 Malvern Panalytical
6.1.12 Bruker Corporation
A selection of companies mentioned in this report includes:
- Agilent Technologies, Inc.
- NanoTemper Technologies
- Horiba, Ltd
- Perkinelmer, Inc.
- Setaram Instrumentation
- Shimadzu Corporation
- Spectris PLC
- Thermo Fisher Scientific
- Unchained Labs
- Danaher Corporation (Molecular Devices LLC–FORTEBIO)
- Malvern Panalytical
- Bruker Corporation