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Liver Diseases Therapeutics Market - Global Forecast 2025-2030

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    Report

  • 180 Pages
  • October 2025
  • Region: Global
  • 360iResearch™
  • ID: 4904957
UP TO OFF until Jan 01st 2026
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Senior executives in the liver diseases therapeutics market confront continual change and complexity—requiring agile leadership to manage evolving clinical practices, regulatory adjustments, and opportunities for innovation within a dynamic global landscape.

Liver Diseases Therapeutics Market Snapshot

The global liver diseases therapeutics market is estimated at USD 18.76 billion in 2024 and is projected to reach USD 20.26 billion by 2025, with the potential to achieve USD 30 billion by 2030. This expansion is underpinned by a Compound Annual Growth Rate (CAGR) of 8.13%, reflecting accelerating innovation in therapies focused on chronic and complex hepatic conditions. Continued investment in research and development, strengthening pharmaceutical pipelines, and a growing focus on patient-centered healthcare are increasing the depth and breadth of available treatment options. Companies actively pursue innovative delivery methods and advancements in clinical protocols to optimize patient results while responding to rising clinical and market demands.

Scope & Segmentation: Strategic Domains in the Liver Diseases Therapeutics Market

  • Disease Types: Includes alcoholic liver disease, hepatitis B and C, primary hepatic malignancies such as hepatocellular carcinoma and cholangiocarcinoma, and a variety of nonalcoholic liver disorders. Each category requires distinct therapeutic strategies, highlighting the necessity for ongoing clinical research and tailored treatment approaches.
  • Therapy Types: Consists of biologic immunotherapies, genome-editing treatments, microbiome-targeted modalities, regenerative medicine, advanced cell-based protocols, and innovative small-molecule drugs. These platforms enable personalization of care and improvements in treatment performance.
  • Routes of Administration: Encompasses intravenous, oral, and subcutaneous formulations, enabling acute intervention, long-term management, and facilitation of care delivery in hospital or home settings based on patient and provider preferences.
  • Drug Classes: Covers antifibrotics, antivirals, chemotherapeutic agents, monoclonal antibodies, corticosteroids, and immunosuppressives. This diversity allows clinicians flexibility in designing combination regimens to address disease progression for multiple liver conditions.
  • End Users: Involves hospitals, clinics, and home care organizations, illustrating the adaptation of service models in response to changes in patient expectations, clinical resources, and access priorities.
  • Distribution Channels: Includes hospital pharmacies, online platforms, and retail locations, each playing a role in supporting patient access, streamlining procurement, and strengthening the supply chain in varied regions.
  • Geographical Coverage: Spans the Americas, Europe, Middle East & Africa, and Asia-Pacific. Regional regulatory environments, infrastructure quality, and population health needs significantly influence adoption rates and competitive strategies.
  • Company Coverage: Features organizations such as Gilead Sciences, AbbVie, Merck & Co., Bristol-Myers Squibb, Johnson & Johnson Services, F. Hoffmann-La Roche, Pfizer, Novartis, GlaxoSmithKline, Intercept Pharmaceuticals by Alfasigma, Sanofi, Takeda, Vertex Pharmaceuticals, AstraZeneca, Boehringer Ingelheim, Eli Lilly, Genfit, Astellas Pharma, Moderna, and Alnylam Pharmaceuticals—recognized for driving innovation, collaboration, and next-generation clinical solutions.

Liver Diseases Therapeutics Market: Key Takeaways for Senior Leaders

  • Gene editing and advanced cell therapy solutions require investment in R&D and adjustments to regulatory protocols to facilitate market-ready innovations.
  • Regulatory frameworks are evolving to accept flexible clinical trial models and leverage real-world data, allowing organizations to bring therapies to market more efficiently.
  • Shifting toward value-based care models will affect product positioning and reimbursement, making robust proof-of-value a key determinant in market success.
  • Adaptation to regional diversity—through locally responsive strategies—remains essential for maintaining leadership as regulatory and healthcare infrastructures differ across global markets.
  • Robust partnerships across manufacturing, research, and supply entities provide a foundation for continuous product supply and expedited patient access.
  • Integration of digital health tools supports improved data flow, compliance, and engagement while enabling multidisciplinary, sustainable care frameworks.

Tariff Impact: Strengthening Supply Chain Resilience

Recent updates to U.S. tariff regulations for pharmaceutical inputs have prompted liver diseases therapeutics sector participants to diversify supply networks and utilize contract manufacturing and modular bioprocessing strategies. This approach helps minimize disruption risk, maintain product availability, and ensures alignment between stable supply chains and ambitious business growth initiatives.

Methodology & Data Sources

This market analysis draws on comprehensive secondary research—including clinical guidelines, current patent trends, and peer-reviewed evidence—supplemented by interviews with industry thought leaders and scenario modeling. The integrated methodology produces reliable, actionable insights for strategic risk management and planning in the liver diseases therapeutics sector.

Why This Report Matters

  • Arms executive teams with guidance for navigating regulatory changes and payment models, backing strategic and operational planning in a fast-moving environment.
  • Highlights new business development opportunities by aligning organizational strengths with competitive activity and emerging healthcare needs.
  • Delivers actionable intelligence for stakeholders to forge value-based partnerships and safeguard market standing as the industry changes.

Conclusion

This report offers senior leaders evidence-based perspectives and actionable recommendations for strategic adaptation, enhancing patient-centric care, and building lasting organizational resilience as the market for liver diseases therapeutics evolves.

 

Additional Product Information:

  • Purchase of this report includes 1 year online access with quarterly updates.
  • This report can be updated on request. Please contact our Customer Experience team using the Ask a Question widget on our website.

Table of Contents

1. Preface
1.1. Objectives of the Study
1.2. Market Segmentation & Coverage
1.3. Years Considered for the Study
1.4. Currency & Pricing
1.5. Language
1.6. Stakeholders
2. Research Methodology
3. Executive Summary
4. Market Overview
5. Market Insights
5.1. Adoption of gene editing therapies for hereditary liver disorders with improving delivery vector safety profiles
5.2. Increasing prevalence of liver diseases drives therapeutic need
5.3. Integration of artificial intelligence platforms in optimizing nonalcoholic steatohepatitis clinical trials
5.4. Emerging regulatory pathways support cell-based therapeutic innovations for liver failure and cirrhosis
5.5. Growth of patient-centric remote monitoring solutions for early detection and management of hepatic complications
5.6. Surging venture capital investments fuel early-stage liver therapeutics
5.7. Collaborations between pharmaceutical companies and biotech firms to accelerate liver fibrosis drug candidate pipelines
5.8. Growth of combination small molecule and biologic therapies for advanced hepatocellular carcinoma
5.9. Government initiatives and public awareness drive early detection of liver diseases
5.10. Development of personalized medicine pipelines using multiomic biomarkers to predict patient responses in NASH trials
6. Cumulative Impact of United States Tariffs 2025
7. Cumulative Impact of Artificial Intelligence 2025
8. Liver Diseases Therapeutics Market, by Disease Type
8.1. Alcoholic Liver Disease
8.2. Hepatitis B
8.3. Hepatitis C
8.4. Liver Cancer
8.4.1. Cholangiocarcinoma
8.4.2. Hepatocellular Carcinoma
8.5. Non Alcoholic Lever Disease
9. Liver Diseases Therapeutics Market, by Therapy Type
9.1. Biologic Immunotherapies
9.2. Cell-Based & Regenerative Therapy
9.3. Gene Therapy
9.4. Microbiome-Modulating Therapies
9.5. Small-Molecule Drugs
10. Liver Diseases Therapeutics Market, by Route Of Administration
10.1. Intravenous
10.2. Oral
10.3. Subcutaneous
11. Liver Diseases Therapeutics Market, by Drug Class
11.1. Antifibrotic
11.1.1. Pirfenidone
11.1.2. Simtuzumab
11.2. Antivirals
11.2.1. Interferons
11.2.2. NS5A Inhibitors
11.2.3. NS5B Polymerase Inhibitors
11.2.4. Nucleotide/Nucleoside Analogues
11.2.5. Protease Inhibitors
11.3. Chemotherapeutic
11.4. Corticosteroids
11.5. Immunosuppressants
11.6. Monoclonal Antibody
12. Liver Diseases Therapeutics Market, by End User
12.1. Clinic
12.2. Home Care Settings
12.3. Hospital
13. Liver Diseases Therapeutics Market, by Distribution Channel
13.1. Hospital Pharmacy
13.2. Online Pharmacy
13.3. Retail Pharmacy
14. Liver Diseases Therapeutics Market, by Region
14.1. Americas
14.1.1. North America
14.1.2. Latin America
14.2. Europe, Middle East & Africa
14.2.1. Europe
14.2.2. Middle East
14.2.3. Africa
14.3. Asia-Pacific
15. Liver Diseases Therapeutics Market, by Group
15.1. ASEAN
15.2. GCC
15.3. European Union
15.4. BRICS
15.5. G7
15.6. NATO
16. Liver Diseases Therapeutics Market, by Country
16.1. United States
16.2. Canada
16.3. Mexico
16.4. Brazil
16.5. United Kingdom
16.6. Germany
16.7. France
16.8. Russia
16.9. Italy
16.10. Spain
16.11. China
16.12. India
16.13. Japan
16.14. Australia
16.15. South Korea
17. Competitive Landscape
17.1. Market Share Analysis, 2024
17.2. FPNV Positioning Matrix, 2024
17.3. Competitive Analysis
17.3.1. Gilead Sciences, Inc.
17.3.2. AbbVie Inc.
17.3.3. Merck & Co., Inc.
17.3.4. Bristol-Myers Squibb Company
17.3.5. Johnson & Johnson Services Inc.
17.3.6. F. Hoffmann-La Roche Ltd.
17.3.7. Pfizer Inc.
17.3.8. Novartis AG
17.3.9. GlaxoSmithKline plc
17.3.10. Intercept Pharmaceuticals, Inc. by Alfasigma S.p.A.
17.3.11. Sanofi SA
17.3.12. Takeda Pharmaceutical Company Limited
17.3.13. Vertex Pharmaceuticals Incorporated
17.3.14. AstraZeneca PLC
17.3.15. C. H. Boehringer Sohn AG & Co. KG
17.3.16. Eli Lilly and Company
17.3.17. Genfit S.A.
17.3.18. Astellas Pharma Inc.
17.3.19. Moderna, Inc.
17.3.20. Alnylam Pharmaceuticals, Inc.

Companies Mentioned

The companies profiled in this Liver Diseases Therapeutics market report include:
  • Gilead Sciences, Inc.
  • AbbVie Inc.
  • Merck & Co., Inc.
  • Bristol-Myers Squibb Company
  • Johnson & Johnson Services Inc.
  • F. Hoffmann-La Roche Ltd.
  • Pfizer Inc.
  • Novartis AG
  • GlaxoSmithKline plc
  • Intercept Pharmaceuticals, Inc. by Alfasigma S.p.A.
  • Sanofi SA
  • Takeda Pharmaceutical Company Limited
  • Vertex Pharmaceuticals Incorporated
  • AstraZeneca PLC
  • C. H. Boehringer Sohn AG & Co. KG
  • Eli Lilly and Company
  • Genfit S.A.
  • Astellas Pharma Inc.
  • Moderna, Inc.
  • Alnylam Pharmaceuticals, Inc.

Table Information