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Peripartum Cardiomyopathy. From Pathophysiology to Management

  • Book
  • January 2021
  • Elsevier Science and Technology
  • ID: 4911809

Peripartum Cardiomyopathy: From Pathophysiology to Management covers the pathophysiology and the heterogenous mode of presentation of PPCM to assist in risk stratification and provide a guide for the acute and long-term management of women affected by this serious condition. Each chapter provides structured figures and practical algorithms as well as prints of electrocardiograms, echocardiographic, MRI images and several case studies throughout. This title is a must have reference for those doing basic research in this area as well as all healthcare providers caring for peripartum women, including obstetricians, general physicians, cardiologists, intensivists, as well as nurses caring for heart failure patients.

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Table of Contents

1. Foreword by editor 2. What is known about etiology and pathophysiology of PPCM? 3. How to diagnose the condition? 4. How to risk stratify women with newly diagnosed PPCM? 5. How to manage a woman presenting with acute PPCM? 6. What needs to be known about longer-term management and prognosis? 7. Is a subsequent pregnancy safe? 8. How to advise on safe delivery and best contraception? 9. What can be learned from the Global Registry on PPCM? 10. What are the gaps in knowledge on PPCM?


Karen Silwa MD, PhD; Director, Hatter Institute for Cardiovascular Research in Africa & CHI; Faculty of Health Sciences, University of Cape Town, South Africa. Prof. Sliwa is the Director of the Hatter Institute for Cardiovascular Research in Africa, University of Cape Town, South Africa. Born in Germany, studying Medicine, undergoing training as a physician and cardiologist in many countries, she has lived in South Africa since 1992. Cardiovascular disease in pregnancy and postpartum is one of her main areas of clinical and pathophysiological research. Recent progress in understanding underlying pathophysiology of Peripartum Cardiomyopathy, enabled by novel experimental approaches interlinked with unique international efforts has led to great progress in awareness and management of the disease. To coordinate efforts even better, a Study Group, 'Peripartum Cardiomyopathy', of the Heart Failure Association of the European Cardiac Society, chaired by her and others was formed in 2009. That has led to a large international registry under the EuroObservational Programe on Peripartum Cardiomyopathy. In recognition of her work Prof Sliwa has received several awards, including the South Africa/Germany Year of Science Celebrations Award (2012), German Cardiac Society Paul Morawitz Award for Exceptional Cardiovascular Research (2013) and the Cardiac Disease in Pregnancy award (2014) and the Africa's most influential women in Business & Government life-time award (2015 and 2016). In 2017 Prof. Sliwa was awarded an Honorary Doctorate University Diderot-Sorbonne, Paris, France. This is the Highest Distinction of French Universities as a recognition towards Research and Global Engagement which is awarded by the French University Research Board and approved by the French Ministry of Foreign Affairs. She serves on many editorial boards and is also an editorial consultant to 'The Lancet'. Furthermore, she is former president of the South African Heart Association and on the board of the South African Heart Failure Society, which was established under her leadership in 2005. She is president-elect of the World Heart Federation (2017-2018), serves on the European Cardiac Society International Affairs Committee and is Vice-president South and board member of the Pan African Society of Cardiology. She has been the Faculty of Health Science Deputy Dean for Research from 1 March 2017-30 April 2018.