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Artificial Intelligence and Deep Learning in Pathology

  • Book

  • June 2020
  • Elsevier Health Science
  • ID: 4911884

Recent advances in computational algorithms, along with the advent of whole slide imaging as a platform for embedding artificial intelligence (AI), are transforming pattern recognition and image interpretation for diagnosis and prognosis. Yet most pathologists have just a passing knowledge of data mining, machine learning, and AI, and little exposure to the vast potential of these powerful new tools for medicine in general and pathology in particular. In Artificial Intelligence and Deep Learning in Pathology, with a team of experts, Dr. Stanley Cohen covers the nuts and bolts of all aspects of machine learning, up to and including AI, bringing familiarity and understanding to pathologists at all levels of experience.

  • Focuses heavily on applications in medicine, especially pathology, making unfamiliar material accessible and avoiding complex mathematics whenever possible.

  • Covers digital pathology as a platform for primary diagnosis and augmentation via deep learning, whole slide imaging for 2D and 3D analysis, and general principles of image analysis and deep learning.
  • Discusses and explains recent accomplishments such as algorithms used to diagnose skin cancer from photographs, AI-based platforms developed to identify lesions of the retina, using computer vision to interpret electrocardiograms, identifying mitoses in cancer using learning algorithms vs. signal processing algorithms, and many more.

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Table of Contents

- The evolution of machine learning: past, present, and future

Stanley Cohen

- The basics of machine learning: strategies and techniques

Stanley Cohen

- Overview of advanced neural network architectures

Benjamin R. Mitchell

- Complexity in the use of artificial intelligence in anatomic pathology

Stanley Cohen

- Dealing with data: strategies of preprocessing data

Stanley Cohen

- Digital pathology as a platform for primary diagnosis and augmentation via deep learning.

Anil V. Parwani

- Applications of artificial intelligence for image enhancement in pathology

Tanishq Abraham, Austin Todd, Daniel A. Orringer and Richard Levenson

- Precision medicine in digital pathology via image analysis and machine learning

Peter D. Caie, Neofytos Dimitriou and Ognjen Arandjelovi'c

- Artificial intelligence methods for predictive image-based grading of human cancers

Gerardo Fernandez, Abishek Sainath Madduri, Bahram Marami, Marcel Prastawa, Richard Scott, Jack Zeineh and Michael Donovan

- Artificial intelligence and the interplay between tumor and immunity

Joel Haskin Saltz and Rajarsi Gupta

- Overview of the role of artificial intelligence in pathology: the computer as a pathology digital assistant

John E. Tomaszewski


Stanley Cohen PhD, MD. Dr. Cohen is currently interested in integrating computational imaging with digital workflows. He previously served as President of the American Society for Investigative Pathology (ASIP) and Treasurer and Member of the Executive Board of FASEB. Science-related activities also include chairmanships of study sections for the NIH and DOD and membership on multiple editorial boards. He is currently the Associate Editor for digital and computational pathology and artificial intelligence topic category for the American Journal of Pathology. He is a Senior Fellow of the Association of Pathology Chairs and Co-Chair of the ASIP Special Interest Group on Digital and Computational Pathology. Awards include the Gold-Headed Cane (ASIP) and the Golden Goose Award (AAAS). He is a member of the Digital Pathology Association (DPA), the Board of the International Academy of Digital Pathology (IADP), and Chair of the External Advisory Board of the Alpert Foundation.