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Seasonal Influenza Vaccines: Forecast in Asia-Pacific Markets to 2028

  • ID: 4912014
  • Report
  • December 2019
  • Region: Asia Pacific
  • 104 pages
  • GlobalData
1h Free Analyst Time

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FEATURED COMPANIES

  • Cadila
  • Denka Seiken
  • Medicago
  • Mitsubishi Tanabe
  • Sanofi
  • Seqirus
  • MORE
Seasonal Influenza Vaccines: Forecast in Asia-Pacific Markets to 2028

Summary

Seasonal influenza is a viral infection that occurs annually in the winter months from December to March/April in the Northern Hemisphere and from May to August/September in the Southern Hemisphere, though most of India follows Southern Hemisphere seasonality Two types of influenza virus, type A and B, are responsible for the majority of seasonal influenza infections in humans, and due to frequent virus mutations annual vaccination is recommended. The WHO estimates three to five million cases of severe seasonal influenza infections and 290,000 to 650,000 influenza-related respiratory deaths, most of them in the elderly population. Therefore, many countries recommend annual immunization against seasonal influenza, especially for high-risk groups such as young children, pregnant women, elderly people, and people with chronic diseases, but seasonal influenza is not on the national immunization schedule in China and India.

Immunization provides the best protection against the influenza virus and vaccines have been available for decades with a recent switch from trivalent to quadrivalent vaccines that protect against each two influenza type A and two B strains. Traditionally, seasonal influenza vaccines have been produced in eggs, but a slow manufacturing process and viral egg-adaptations have led to a push for cell-based and recombinant vaccine production methods in recent years.

During the 10-year forecast period, there are nine pipeline products that are on track to launch, driving a forecast growth in the 3GM from $914M in 2018 to $1.05B in 2028, which represents a CAGR of 1.4%.

The late stage pipeline for seasonal influenza vaccines in the 3GM includes the first quadrivalent seasonal influenza vaccines in China from Sinovac, Chongqing Zhifei, and Wuhan, as well as a quadrivalent formulation of Fluad. Quadrivalent live-attenuated vaccines will launch in India (from the Serum Institute) and Japan (AstraZeneca’s FluMist, licensed by Daiichi Sankyo). Furthermore, two new inactivated quadrivalent vaccines from Biken and Denka Seiken will launch during the forecast period, as well as a novel plant-based influenza vaccine in Japan.

Medicago’s MDG-2271 will be the first non-egg-based vaccine to launch in the 3GM, addressing the urgent unmet need of influenza vaccine efficacy by shortening production time and minimizing virus mutations.

Another major unmet need in the 3GM is a high vaccination rate and the lack of government support for seasonal influenza immunization in China and India, resulting in vaccination rates around 2%. Vaccination rates in Japan are projected to remain low due to vaccine hesitancy and skepticism.

Key Questions Answered -
  • How will the seasonal influenza vaccine market landscape in the 3GM (China, India Japan) change from 2018-2028?
  • What are the most promising late-stage pipeline products for seasonal influenza vaccination?
  • How do the clinical and commercial attributes of late-stage pipeline products compare with one another, and against existing immunization options?
  • What are the remaining unmet needs in seasonal influenza immunization?
  • What drivers and barriers will affect seasonal influenza vaccine sales in the 3GM over the forecast period?
Scope
  • Overview of seasonal influenza, including epidemiology, etiology, pathophysiology, symptoms, diagnosis, and current management strategies.
  • Topline Seasonal influenza market revenue from 2018-2028. Annual cost of immunization and major pipeline product sales in this forecast period are included.
  • Key topics covered include current vaccination options, unmet needs and opportunities, and the drivers and barriers affecting seasonal influenza vaccine sales in the 3GM.
  • Pipeline analysis: comprehensive data split across different phases, emerging novel trends under development, synopses of innovative early-stage projects, and detailed analysis of late-stage pipeline products.
  • Analysis of the current and future market competition in the APAC seasonal influenza vaccine market. Insightful review of the key industry drivers, restraints and challenges. Each trend is independently researched to provide qualitative analysis of its implications.
Reasons to buy

The report will enable you to -
  • Develop and design your in-licensing and out-licensing strategies through a review of pipeline products and technologies, and by identifying the companies with the most robust pipeline.
  • Develop business strategies by understanding the trends shaping and driving the APAC seasonal influenza vaccine market.
  • Drive revenues by understanding the key trends, innovative products and technologies, market segments, and companies likely to impact the seasonal influenza vaccine market in the future.
  • Formulate effective sales and marketing strategies by understanding the competitive landscape and by analyzing the performance of various competitors.
  • Identify emerging players with potentially strong product portfolios and create effective counter-strategies to gain a competitive advantage.
  • Organize your sales and marketing efforts by identifying the market categories and segments that present maximum opportunities for consolidations, investments, and strategic partnerships.
Note: Product cover images may vary from those shown
2 of 3

FEATURED COMPANIES

  • Cadila
  • Denka Seiken
  • Medicago
  • Mitsubishi Tanabe
  • Sanofi
  • Seqirus
  • MORE
1 Seasonal Influenza Vaccines: Executive Summary
1.1 Modest Growth Expected for the Seasonal Influenza Vaccine APAC Market over the Forecast Period from 2018-2028
1.2 Transition from Trivalent to Quadrivalent Influenza Vaccines in China and India, Launch of Specialized Vaccines in Japan
1.3 Higher Seasonal Influenza Vaccination Rates and Better Vaccine Efficacy Are Major Unmet Needs
1.4 Quadrivalent Inactivated and Live-Attenuated Influenza Vaccines Will Launch in China and India, Plant-Based Vaccine in Japan
1.5 What Do Physicians Think?

2 Introduction
2.1 Catalyst
2.2 Related Reports
2.3 Upcoming Related Reports

3 Disease Overview
3.1 Etiology and Pathophysiology

4 Epidemiology
4.1 Disease Background
4.2 Risk Factors and Comorbidities
4.3 Global and Historical Trends
4.4 Forecast Methodology
4.5 Epidemiological Forecast for Disease Seasonal Influenza (2018-2028)
4.6 Discussion

5 Disease Management in APAC
5.1 Diagnosis and Treatment Overview
5.2 China
5.3 India
5.4 Japan

6 Competitive Assessment
6.1 Overview

7 Unmet Needs and Opportunity Assessment in APAC
7.1 Overview
7.2 Immunization Programs Including the Elderly and Children
7.3 Enhanced Vaccine Efficacy in High-Risk Groups
7.4 Public Opinion of Seasonal Influenza Vaccines: Awareness, Hesitancy, and Skepticism
7.5 Vaccines Leveraging Improved Manufacturing Technologies and Featuring Broader Influenza Strain Coverage

8 Pipeline Assessment in APAC
8.1 Overview
8.2 Promising Drugs in Clinical Development

9 Current and Future Players in APAC
9.1 Overview
9.2 Trends in Corporate Strategy
9.3 Company Portfolio Assessment

10 Market Outlook in APAC
10.1 Global Markets
10.2 China
10.3 India
10.4 Japan

11 Appendix
11.1 Bibliography
11.2 Abbreviations
11.3 Methodology
11.4 Primary Research - KOLs Interviewed for This Report
11.5 Primary Research - Prescriber Survey
11.6 About the Authors
11.7 About the Author
11.8 Contact Us
11.9 Disclaimer

List of Tables
Table 1: Seasonal Influenza Vaccines: Key Metrics in the 3GM in APAC
Table 2: Influenza Symptoms
Table 3: Risk Factors and Comorbidities for Seasonal Influenza
Table 4: National Vaccination Recommendations for Seasonal Influenza
Table 5: Main Vaccines and Targeted Population for Routine Administration in China
Table 6: Main Vaccines and Targeted Population for Routine Administration in India
Table 7: Main Vaccines and Targeted Population for Routine Administration in Japan
Table 8: Leading Vaccines for Seasonal Influenza, 2019
Table 9: Takeda’s Disease Portfolio Assessment, 2019
Table 10: Denka Seiken’s Disease Portfolio Assessment, 2019
Table 11: Mitsubishi Tanabe’s Disease Portfolio Assessment, 2019
Table 12: Sanofi’s Disease Portfolio Assessment, 2019
Table 13: Seqirus’ Disease Portfolio Assessment, 2019
Table 14: Serum Institute’s Disease Portfolio Assessment, 2019
Table 15: Cadila’s Disease Portfolio Assessment, 2019
Table 16: Sinovac’s Disease Portfolio Assessment, 2019
Table 17: Medicago’s Disease Portfolio Assessment, 2019
Table 18: Other Companies’ Disease Portfolio Assessment, 2019
Table 19: Seasonal influenza Vaccine Market - Global Drivers and Barriers, 2018-2028
Table 20: Key Events Impacting Sales for Seasonal influenza Vaccines in China, 2018-2028
Table 21: Seasonal Influenza Vaccine Market - Drivers and Barriers in China, 2018-2028
Table 22: Key Events Impacting Sales for Seasonal Influenza Vaccines in India, 2018-2028
Table 23: Seasonal Influenza Vaccines Market - Drivers and Barriers in India, 2018-2028
Table 24: Key Events Impacting Sales for Seasonal Influenza Vaccines in Japan, 2018-2028
Table 25: Seasonal Influenza Vaccines Market - Global Drivers and Barriers in Japan, 2018-2028
Table 26: Key Historical and Projected Launch Dates for Seasonal Influenza Vaccines
Table 27: High-Prescribing Physicians (non-KOLs) Surveyed, By Country

List of Figures
Figure 1: APAC 3GM Sales Forecast by Country for Seasonal Influenza Vaccines in 2018 and 2028
Figure 2: Analysis of the Company Portfolio Gap in Seasonal Influenza Vaccines During the Forecast Period
Figure 3: Competitive Assessment of the Late-Stage Pipeline Agents that researchers Expects to Be Licensed for the Prevention of Seasonal Influenza During the Forecast Period
Figure 4: Influenza Virus Structure
Figure 5: Diagnosed Incidence of Lab-Confirmed Seasonal Influenza, Men and Women, All Ages, Cases per 100,000 Population, 2018
Figure 6: 3GM, Sources Used and Not Used for Diagnosed Incident Cases of Lab-Confirmed Seasonal Influenza
Figure 7: 3GM, Sources Used for Lab-Confirmed Seasonal Influenza Mortality
Figure 8: 3GM, Sources Used for Proportion of People Receiving Seasonal Influenza Vaccination
Figure 9: 3GM, Diagnosed Incident Cases of Lab-Confirmed Seasonal Influenza, Both Sexes, All Ages, 2018
Figure 10: 3GM, Age-Specific Diagnosed Incident Cases of Lab-Confirmed Seasonal Influenza, Both Sexes, All Ages, 2018, N
Figure 11: 3GM, Sex-Specific Diagnosed Incident Cases of Lab-Confirmed Seasonal Influenza, All Ages, 2018, N
Figure 12: 3GM, Lab-Confirmed Seasonal Influenza Mortality, Both Sexes, All Ages, 2018, N
Figure 13: 3GM, Age-Specific Cases of People Receiving Seasonal Influenza Vaccination, Both Sexes, All Ages, 2018, N
Figure 14: Unmet Needs and Opportunities in Seasonal Influenza Vaccination
Figure 15: Overview of the Development Pipeline for Seasonal Influenza Vaccines
Figure 16: Key Phase II/III Trials for the Promising Pipeline Agents that researchers Expects to Be Licensed for Seasonal Influenza in the 3GM During the Forecast Period
Figure 17: Competitive Assessment of the Late-Stage Pipeline Agents that researchers Expects to Be Licensed for Seasonal Influenza Immunization During the Forecast Period
Figure 18: Analysis of the Company Portfolio Gap in Seasonal Influenza Vaccines During the Forecast Period
Figure 19: APAC (3GM) Sales Forecast by Country for Seasonal Influenza Vaccines in 2018 and 2028
Figure 20: Sales Forecast by Class for Seasonal Influenza Vaccines in China in 2018 and 2028
Figure 21: Sales Forecast by Class for Seasonal Influenza Vaccines in India in 2018 and 2028
Figure 22: Sales Forecast by Class for Seasonal Influenza Vaccines in Japan in 2018 and 2028
Note: Product cover images may vary from those shown
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  • Cadila
  • Denka Seiken
  • Medicago
  • Mitsubishi Tanabe
  • Sanofi
  • Seqirus
  • Serum Institute of India
  • Sinovac
  • Takeda
Note: Product cover images may vary from those shown
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