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Systemic Lupus Erythematosus and Lupus Nephritis: Epidemiology Forecast to 2028

  • ID: 5004129
  • Report
  • January 2020
  • Region: Global
  • 57 pages
  • GlobalData
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Systemic Lupus Erythematosus and Lupus Nephritis: Epidemiology Forecast to 2028

Summary

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of multifactorial origin that can affect any organ or organ system, resulting in a broad spectrum of clinical manifestations ranging from dermatological involvement to multi-organ failure with episodes of relapses and remissions. Because of its dynamic nature, this disease has an unpredictable natural course leading to high rates of morbidity and even death (Bertsias, Cervera and Boumpas, 2012; Bhattacharya et al., 2011). Lupus nephritis (LN) or lupus glomerulonephritis is a complication of SLE in which the kidneys are affected. LN is a major contributor to morbidity and mortality among SLE patients (Bhattacharya et al., 2011; O'Neill and Cervera, 2010).

The publisher epidemiologists utilized historical data obtained from peer-reviewed articles and reports to build the forecast for the diagnosed incident cases and the diagnosed prevalent cases of SLE and LN in the 7MM. Epidemiologists applied the incidence and prevalence of SLE and LN drawn from the above sources to each country's population to calculate the number of estimated diagnosed incident cases and diagnosed prevalent cases for SLE and LN.

The following data describes the epidemiology of SLE and LN. In the 7MM, epidemiologists forecast an increase in the diagnosed prevalent cases of SLE from 571,021 cases in 2018 to 600,663 cases in 2028, at an Annual Growth Rate (AGR) of 0.52%. When examining the AGR of diagnosed prevalence of SLE in individual markets, epidemiologists forecast that the UK will see the highest AGR of 0.79% during the forecast period, while Germany will show the lowest negative AGR of 0.12%. In 2018, the 7MM had 98,620 diagnosed prevalent cases of LN, expected to increase to 102,939 diagnosed prevalent cases by 2028, at an AGR of 0.44%.

Scope
  • The Systemic Lupus Erythematosus and Lupus Nephritis Epidemiology Report provides an overview of the risk factors and global trends of Systemic Lupus Erythematosus (SLE) and Lupus Nephritis (LN) in the seven major markets (7MM: US, France, Germany, Italy, Spain, UK, and Japan).
  • This report includes a 10-year epidemiological forecast of the diagnosed incident and diagnosed prevalent cases of SLE segmented by age, and sex, and the diagnosed prevalent cases are further segmented by severity.
  • The report also includes a 10-year epidemiological forecast for various comorbidities of SLE. An epidemiological forecast of the diagnosed incident and diagnosed prevalent cases of LN among pediatric population and adult population for the 7MM is also incorporated.
  • Additionally, the report includes the diagnosed prevalent cases of LN segmented by World Health Organization (WHO) and International Society of Nephrology (ISN)/Renal Pathology Society (RPS) classification into Classes I-VI.
  • The SLE and LN epidemiology report is written and developed by Masters- and PhD-level epidemiologists.
  • The Epidemiology Report is in-depth, high quality, transparent and market-driven, providing expert analysis of disease trends in the 7MM.
  • The Epidemiology report is easy to navigate, interactive with dashboards, and epidemiology-based with transparent and consistent methodologies. Moreover, the report supports data presented in the report and showcases disease trends over a 10-year forecast period using reputable sources.
Reasons to buy

The SLE and LN Epidemiology series will allow you to:
  • Develop business strategies by understanding the trends shaping and driving the global SLE and LN markets.
  • Quantify patient populations in the global SLE and LN markets to improve product design, pricing, and launch plans.
  • Organize sales and marketing efforts by identifying the age groups and sex that present the best opportunities for SLE and LN therapeutics in each of the markets covered.
  • Understand magnitude of SLE and LN population by its severity.
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1.1 List of Tables
1.2 List of Figures

2 Systemic Lupus Erythematosus and Lupus Nephritis: Executive Summary
2.1 Catalyst
2.2 Related Reports
2.3 Upcoming Reports

3 Epidemiology
3.1 Disease Background
3.2 Risk Factors and Comorbidities
3.3 Global and Historical Trends
3.4 Forecast Methodology
3.4.1 Sources
3.4.2 Forecast Assumptions and Methods
3.4.3 Forecast Assumptions and Methods: Diagnosed Incident Cases of SLE
3.4.4 Forecast Assumptions and Methods: Diagnosed Prevalent Cases of SLE
3.4.5 Forecast Assumptions and Methods: Diagnosed Prevalent Cases of SLE by Severity
3.4.6 Forecast Assumptions and Methods: Diagnosed Prevalent Cases of SLE by Comorbidities
3.4.7 Forecast Assumptions and Methods: Diagnosed Incident Cases of LN
3.4.8 Forecast Assumptions and Methods: Diagnosed Prevalent Cases of LN
3.4.9 Forecast Assumptions and Methods: Diagnosed Prevalent Cases of LN by Severity, Based on WHO Classifications
3.4.10 Forecast Assumptions and Methods: Diagnosed Prevalent Cases of LN by Severity, Based on ISN/RPS Classification
3.5 Epidemiological Forecast for SLE and LN (2018-2028)
3.5.1 Diagnosed Incident Cases of SLE
3.5.2 Age-Specific Diagnosed Incident Cases of SLE
3.5.3 Sex-Specific Diagnosed Incident Cases of SLE
3.5.4 Diagnosed Incident Cases of LN
3.5.5 Diagnosed Prevalent Cases of SLE
3.5.6 Age-Specific Diagnosed Prevalent Cases of SLE
3.5.7 Sex-Specific Diagnosed Prevalent Cases of SLE
3.5.8 Diagnosed Prevalent Cases of SLE by Severity
3.5.9 Diagnosed Prevalent Cases of SLE by Comorbidities
3.5.10 Diagnosed Prevalent Cases of LN
3.5.11 Diagnosed Prevalent Cases of LN by Severity, Based on WHO Classifications
3.5.12 Diagnosed Prevalent Cases of LN by Severity, Based on ISN/RPS Classifications
3.6 Discussion
3.6.1 Epidemiological Forecast Insight
3.6.2 Limitations of the Analysis
3.6.3 Strengths of the Analysis

4 Appendix
4.1 Bibliography
4.2 Primary Research - Prescriber Survey
4.3 About the Authors
4.3.1 Epidemiologist
4.3.2 Reviewers
4.3.3 Global Director of Therapy Analysis and Epidemiology
4.3.4 Global Head and EVP of Healthcare Operations and Strategy
4.4 About the Publisher
4.5 Contact Us
4.6 Disclaimer

List of Tables
Table 1: Summary of Newly Added Data Types
Table 2: Summary of Updated Data Types
Table 3: Risk Factors and Comorbidities for SLE
Table 4: High-Prescribing Physicians (non-KOLs) Surveyed for Severity of SLE, By Country
Table 5: High-Prescribing Physicians (non-KOLs) Surveyed for Comorbidities of SLE, By Country

List of Figures
Figure 1: 7MM, Diagnosed Prevalent Cases of SLE, Both Sexes, N, All Ages, 2018 and 2028
Figure 2: 7MM, Diagnosed Prevalent Cases of LN, Both Sexes, N, All Ages, 2018 and 2028
Figure 3: 7MM, Diagnosed Prevalence of SLE, Men and Women, %, All Ages, 2018
Figure 4: 7MM, Diagnosed Prevalence of LN, Men and Women, %, All Ages, 2018
Figure 5: 7MM, Sources Used and Not Used to Forecast the Diagnosed Incident Cases of SLE
Figure 6: 7MM, Sources Used and Not Used to Forecast the Diagnosed Prevalent Cases of SLE
Figure 7: 7MM, Sources Used to Forecast the Diagnosed Incident Cases of LN
Figure 8: 7MM, Sources Used to Forecast the Diagnosed Prevalent Cases of LN
Figure 9: 7MM, Sources Used to Forecast the Diagnosed Prevalent Cases of LN by Severity, Based on WHO Classification
Figure 10: 7MM, Sources Used to Forecast the Diagnosed Prevalent Cases of LN by Severity, Based on ISN/RPS Classification
Figure 11: 7MM, Diagnosed Incident Cases of SLE, N, Both Sexes, All Ages, 2018
Figure 12: 7MM, Diagnosed Incident Cases of SLE by Age, N, Both Sexes, 2018
Figure 13: 7MM, Diagnosed Incident Cases of SLE by Sex, N, All Ages, 2018
Figure 14: 7MM, Diagnosed Incident Cases of LN, N, Both Sexes, All Ages, 2018
Figure 15: 7MM, Diagnosed Prevalent Cases of SLE, N, Both Sexes, All Ages, 2018
Figure 16: 7MM, Diagnosed Prevalent Cases of SLE by Age, N, Both Sexes, 2018
Figure 17: 7MM, Diagnosed Prevalent Cases of SLE by Sex, N, All Ages, 2018
Figure 18: 7MM, Diagnosed Prevalent Cases of SLE by Severity, N, All Ages, 2018
Figure 19: 7MM, Diagnosed Prevalent Cases of SLE by Comorbidities, N, All Ages, 2018
Figure 20: 7MM, Diagnosed Prevalent Cases of LN, N, Both Sexes, All Ages, 2018
Figure 21: 7MM, Diagnosed Prevalent Cases of LN by Severity Based on WHO Classification, N, Both Sexes, All Ages, 2018
Figure 22: 7MM, Diagnosed Prevalent Cases of LN by Severity Based on ISN/RPS Classification, N, Both Sexes, All Ages, 2018
Note: Product cover images may vary from those shown
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