Biologically functional ceramic materials have been known about for several decades, like phosphate cements and gypsum, and they are within the zeroth generation. Modern and artificially synthesized bioceramics include amorphous materials in the Bioglass® family that were developed in the early 1970's and derivative glass ceramics such as Bioverit® and Cerabone A-W® that came in 1980's. They are from the 2nd generation of materials, and mostly applicable to bone replacement or bone defect fillers. Since the late 1990's, newer technologies have been introduced to the biologically functional material fields; they are the syntheses of organic-inorganic hybrids of micro- and macroscopic scales as well as nano-scales, organic fragment-covered ceramic particles of varied sizes, with light-controlling abilities to modify the frequency of light, in addition synthesis of high strength and high-tribological durability that had not been available before. With the advent of additive manufacturing technology employing lasers, electron beams, and printers, clinical materials of complicated porous structures are now easily prepared. These materials are of the 3rd generation.
This book will cover almost all kinds of such 3rd generation ceramic and ceramic-related biomaterials. This book conveys the current state-of-the-art on the science and technology of bioceramics, from nano-size dots or particles to macro-scale architectures, of a wide range of constitutions including quantum dots with peptide fragments, meso-scale therapeutic particles designed to involve drugs or genes, mesoporous organic-inorganic hybrids, nano-structured oxide layers on metals and alloys.
- Comprehensively covers all aspects (research/experimental and commercial products) related to the latest progresses in bioceramic science, technology and applications, with emphasis on nanobioceramics
- Pulls together a broad range of materials, concepts, and technologies based on nanomaterials
- Features novel preparation procedures like additive manufacturing (3-D printing and related techniques) that have also been introduced and practiced for forming complicated architectures
- Features innovative 3rd generation ceramic and ceramic-related biomaterials
1. Introduction 2. Importance of nano-structured surfaces 3. Nano-structured TiO2 layers on Ti for bone-bonding 4. Organic modification of magnetite nanoparticles for biomedical applications 5. NIR excitation of rare earth ions for diagnosis and bioimaging 6. Organic-Inorganic Nanohybrid Particles for Biomedical Applications 7. Incorporation behavior and biomedical applications of inorganic-layered compounds 8. Nano apatite formation on DCPD 9. Bone structure and formation: A new perspective 10. Sol-gel preparation of titanium oxide and hydroxyapatite microparticles for blood purification 11. Design of silica-doped calcium carbonates and their composites for biomedical use 12. Ceramics for Artificial Joints: Alumina, Zirconia and Alumina-Zirconia composites 13. Chemistry of bioceramics in joint arthroplasty: the missing key 14. Robocasting of mesoporous bioactive glasses (MBGs) 15. Glass and glass ceramics for tissue engineering 16. Bioactive ceramics: past and future 17. PILP and bone regeneration 18. Electrospinning and Nanofibrous Structures for Biomedical Applications
Dr. Akiyoshi Osaka is a Project Professor and Professor Emeritus of Okayama University, Japan, associated with Faculty of Engineering, and also affiliated with the School of Materials Science and Engineering, Henan University of Science and Technology, PR China, as a Distinguished Professor under the 1000 Talents Plan. He earned B.E. from Okayama University, and M.E. and PhD from Kyoto University. His research area extends from glass and glass ceramics in borates, phosphates, silicates, tellurites, borosilicates, or borophosphates, and to the sol-gel preparation of oxides and organic-inorganic hybrids as well as their biomedical applications. He is an author of over 250 publications and over 10 book chapters. Dr. Osaka was awarded for his achievements with Excellent Ceramic Scientist Award from the Ceramic Society of Japan 1994. He has been elected as Fellow of the Ceramic Society of Japan.
Dr. Roger Narayan is a Professor in the Joint Department of Biomedical Engineering at the University of North Carolina and North Carolina State University. He is an author of over two hundred publications as well as several book chapters on processing of biomedical materials. He currently serves as an editorial board member for several academic journals, including as editor-in-chief of Medical Devices & Sensors (Wiley) and associate editor of Applied Physics Reviews (AIP Publishing). Dr. Narayan has also edited several books, including the textbook Biomedical Materials (Springer), the handbook Materials for Medical Devices (ASM International), and The Encyclopedia of Biomedical Engineering (Elsevier). He has previously served as director of the TMS Functional Materials Division and the ASM International Emerging Technologies Awareness Committee; he currently serves as chair of the American Ceramic Society Bioceramics Division. As the 2016-7 ASME Swanson Fellow, Dr. Narayan worked with America Makes, the US national additive manufacturing institute, on several activities to disseminate additive manufacturing technology, including the development of an workforce/education/outreach roadmap for additive manufacturing, and the development of a repository containing educational materials related to additive manufacturing. Dr. Narayan has received several honors for his research activities, including the NCSU Alcoa Foundation Engineering Research Achievement Award, the University of North Carolina Jefferson-Pilot Fellowship in Academic Medicine, the National Science Faculty Early Career Development Award, the Office of Naval Research Young Investigator Award, and the American Ceramic Society Richard M. Fulrath Award. He has been elected as Fellow of AAAS, ASM International, AIMBE, and American Ceramic Society.