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Theory and Applications of Nonparenteral Nanomedicines

  • ID: 5007955
  • Book
  • September 2020
  • Elsevier Science and Technology

Theory and Applications of Nonparenteral Nanomedicines presents thoroughly analysed data and results regarding the potential of nanomedicines conceived by diverse non-parenteral routes. In the context of nanotechnology-based approaches, various routes such as oral, pulmonary, transdermal, delivery and local administration of nanomedicine have been utilized for the delivery of nanomedicine. This book discusses the non-parenteral application of nanomedicine, its regulatory implications, application of mucus penetrating nanocarrier, and detailed chapters on development of nanomedicines developed for drug delivery by various route.

Beginning with a brief introduction to the non-parenteral delivery of nanomedicine and the safety and regulatory implications of the nanoformulations, further chapters discuss the physiology of the biological barriers, the specificity of the nanocarriers as well as their multiple applications. Theory and Applications of Nonparenteral Nanomedicines helps clinical researchers, researchers working in pharmaceutical industries, graduate students, and anyone working in the development of non-parenteral nanomedicines to understand the recent progress in the design and development of nanoformulations compatible with non-parenteral applications.

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1. Introduction: An Overview of the non-parenteral delivery of nanomedicine
2. Challenges in non-parenteral nanomedicine therapy
3. Regulatory implication of non-parenteral nanomedicine
4. Physiology of the biological barriers
5. Mucoadhesive polymers in the design of nanocarrier
6. Mucoadhesive polymers, lipids used in solid lipid nanoparticles
7. Mucus penetrating nanocarrier
8. Nanomedicines developed for ocular drug delivery
9. From the nose to the brain, nanomedicine drug delivery
10. Oral drug delivery of nanomedicines
11. Nanomedicine for inflammatory bowel disease
12. Nanomedicine for vaginal drug delivery
13. Nanomedicine in reproductive biology
14. Regenerative nanomedicine, emerging non-parenteral applications
15. Electrospun nanofibers for wound healing
16. Nanomedicine in pulmonary delivery
17. Nanomedicine and pain management
18. Transdermal delivery of nanomedicine
19. Nanomedicine and insulin delivery
20. Non-parenteral nanoparticles in consumer products
21. Post-operative local administration of nanomedicine
22. Hydrogel for therapeutic delivery of nanomedicine
23. Regulatory pathway to introduce a nanomedicine product on the market at international level
24. Non-parenteral nanoparticles in consumer products
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Prashant Kesharwani Assistant Professor, Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India.

Dr. Prashant Kesharwani is Assistant Professor of Pharmaceutics at the School of Pharmaceutical Education and Research, Jamia Hamdard University, New Delhi, India. He has published more than 150 articles in well reputed international journals and edited 10 international books. Dr. Kesharwani has received several awards, including the 'Ramanujan Fellowship, DST, India-2017', 'Excellence Research Award 2014', 'Young Innovator Award (Gold medal) 2012', 'International Travel Award/Grant from DST (New Delhi) and INSA (CCSTDS, Chennai) 2012', as well as receiving an ICMR Senior Research Fellowship (PhD) and AICTE Junior Research Fellowship (M. Pharm.). He has presented invited talks and presentations at prestigious conferences, supervised students/junior researchers, and actively participated in outreach and scientific dissemination for the service of the wider community. Dr. Kesharwani's current research is focused on the development of nano-engineered drug delivery systems for various diseases.
Sebastien Taurin Associate Professor of Molecular Medicine, Arabian Gulf University, Kingdom of Bahrain.

Dr. Sebastien Taurin is Associate Professor of Molecular Medicine at Arabian Gulf University, Kingdom of Bahrain. He previously worked at the University of Utah in the department of Gynecology and obstetrics and the University of Otago in the Department of Pharmacology and Toxicology. He held a postdoctoral fellowship at the University of Chicago in the Section of Pulmonary and Critical Care Medicine. He is a researcher focused on cancer treatment, cancer cell signaling adaptation and heterogeneity, and modelization.
Khaled Greish Professor of Molecular Medicine, Princes Al-Jawhara Center, Arabian Gulf University, Kingdom of Bahrain.

Dr. Khaled Greish is Professor of Molecular Medicine, and head of the Nano-research unit, at Princes Al-Jawhara Center, Arabian Gulf University, Kingdom of Bahrain. His previous appointments included Senior lecturer of Pharmacology at the University of Otago, New Zealand, and Assistant Professor of Pharmaceutical Chemistry at University of Utah (UT, USA). He has published > 70 peer reviewed papers, and 10 book chapters in the field of targeted anticancer drug delivery. Controlled Release Society (CRS) awarded him the CRS Postdoctoral Achievement Award in 2008 and in 2010; he was elected as member of the CRS College of Fellows. In recognition of his research, University of Otago awarded him "Early Career Awards for Distinction in Research” in 2014. His research focuses on Nanomedicine, tumor vascular biology, and anticancer drug discovery/development.
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