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Theory and Applications of Nonparenteral Nanomedicines

  • ID: 5007955
  • Book
  • September 2020
  • Region: Global
  • 416 Pages
  • Elsevier Science and Technology
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Theory and Applications of Non-parenteral Nanomedicines presents thoroughly analysed data and results regarding the potential of nanomedicines conceived by diverse non-parenteral routes. In the context of nanotechnology-based approaches, various routes such as oral, pulmonary, transdermal, delivery and local administration of nanomedicine have been utilized for the delivery of nanomedicine. This book discusses the non-parenteral application of nanomedicine, its regulatory implications, application of mucus penetrating nanocarrier, and detailed chapters on development of nanomedicines developed for drug delivery by various route.

Beginning with a brief introduction to the non-parenteral delivery of nanomedicine and the safety and regulatory implications of the nanoformulations, further chapters discuss the physiology of the biological barriers, the specificity of the nanocarriers as well as their multiple applications. Theory and Applications of Non-parenteral Nanomedicines helps clinical researchers, researchers working in pharmaceutical industries, graduate students, and anyone working in the development of non-parenteral nanomedicines to understand the recent progress in the design and development of nanoformulations compatible with non-parenteral applications.

  • Contains a comprehensive review of non-parenteral nanomedicines
  • Provides analysis of non-parenteral methods of nanomedicines including regulatory implications and future applications
  • Explores a wide range of promising approaches for non-parenteral drug delivery using the latest advancement in nanomedicine written by experts in industry and academia
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1. Introduction: An Overview of the non-parenteral delivery of nanomedicine
2. Challenges in non-parenteral nanomedicine therapy
3. Regulatory implication of non-parenteral nanomedicine
4. Physiology of the biological barriers
5. Mucoadhesive polymers in the design of nanocarrier
6. Mucoadhesive polymers, lipids used in solid lipid nanoparticles
7. Mucus penetrating nanocarrier
8. Nanomedicines developed for ocular drug delivery
9. From the nose to the brain, nanomedicine drug delivery
10. Oral drug delivery of nanomedicines
11. Nanomedicine for inflammatory bowel disease
12. Nanomedicine for vaginal drug delivery
13. Nanomedicine in reproductive biology
14. Regenerative nanomedicine, emerging non-parenteral applications
15. Electrospun nanofibers for wound healing
16. Nanomedicine in pulmonary delivery
17. Nanomedicine and pain management
18. Transdermal delivery of nanomedicine
19. Nanomedicine and insulin delivery
20. Non-parenteral nanoparticles in consumer products
21. Post-operative local administration of nanomedicine
22. Hydrogel for therapeutic delivery of nanomedicine
23. Regulatory pathway to introduce a nanomedicine product on the market at international level
24. Non-parenteral nanoparticles in consumer products
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Kesharwani, Prashant
Dr. Prashant Kesharwani is currently working as Assistant Professor, Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India. He received his doctoral degree in Pharmaceutical Sciences from the Dr H.S. Gour University (Sagar, India) with Prof N.K Jain's group. He is a recipient of several internationally acclaimed awards viz "Ramanujan Fellowship, DST, India-2017”, "Excellence Research Award-2014”, "Young Innovator Award (Gold medal)-2012”, "International Travel Award/Grant from DST (New Delhi), and INSA (CCSTDS, Chennai)-2012”. He has received ICMR Senior Research Fellowship (in PhD) and AICTE Junior Research Fellowship (in M. Pharm.). After his doctorate, he worked as postdoctoral fellows in the Wayne State University, Detroit (Michigan, USA). Dr. Kesharwani subsequently joined the School of Pharmacy, International Medical University (Malaysia) as lecturer in Pharmaceutical Technology. Subsequently he joined Central Drug Research Institute (CDRI), Lucknow as Ramanujan Fellow. An overarching goal of his current research is the development of nano-engineered drug delivery systems for cancer through with prime focus on dendrimer and polymeric nanomicelles mediated drug delivery systems. Dr. Kesharwani is a co-author on more than 120 publications in high impact factor international journals and 4 international books with total citations of more than 3300 (h index is 27 and i-10 index is 65 as per Google Scholar).
Taurin, Sebastien
Greish, Khaled
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