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Camptothecin and Camptothecin Producing Plants

  • ID: 5018849
  • Book
  • July 2020
  • Region: Global
  • 376 Pages
  • Elsevier Science and Technology
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Camptothecin and Camptothecin Producing Plants: Botany, Chemistry, Anticancer Activity and Biotechnology provides updated information on camptothecin yielding plants, chemical diversity of camptothecin, extraction and exploitation methods, biosynthesis, biotechnological production and enhancement for drug delivery, and pharmacological properties of the drugs with modern approaches. It focuses particularly on camptothecin anticancer properties based on recent developments of biotechnology.

The book presents such topics emphasizing the anticancer activities, biosynthesis, potent derivatives currently undergoing experimental phases, and biotechnological methods to enhance the production. There are many review articles available regarding camptothecin, however this book covers several different aspects of the topic in one single place, making it a reference on camptothecin research.

This book is a valuable source for cancer researchers, oncologists, biotechnologists, pharmacologists and several members of biomedical field interested in camptothecin and its multiple applicability in cancer treatment.

  • Provides information on camptothecin producing plants and their anticancer properties for the development of new treatments
  • Discusses new applications of camptothecin making use of recent biotechnology advancements
  • Encompasses information on pharmacology of camptothecin to leverage new anticancer drugs developments
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1. Introduction (cancers, problems, treatments, anticancerous chemicals, need of anticancerous drugs)
2. Camptothecin: Chemistry, biosynthesis, analogues
Chemical structures and synthesis
3. Pharmacology of Camptothecin and camptothecin producing plants
4. Camptothecin producing plants. Their taxonomy, morphology, identification, distribution and other botanical details (it also includes colour photographs of plants)
5. Micropropagation of Camptothecin producing plants
Camptotheca acuminata
6. Micropropagation of Camptothecin producing plants
Nothapodytes nimmoniana
7. Micropropagation of Camptothecin producing plants
Ophiorrhiza species
8. Biotechnology of Camptothecin producing plants (Camptothecin production through hairy root cultures, suspension cultures, callus cultures etc) - Camptotheca acuminata
8. Biotechnology of Camptothecin producing plants (Camptothecin production through hairy root cultures, suspension cultures, callus cultures etc) - Nothapodytes nimmoniana
9. Biotechnology of Camptothecin producing plants (Camptothecin production through hairy root cultures, suspension cultures, callus cultures etc) Ophiorhiza
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Pullaiah, T.
Prof. T.Pullaiah has retired from active service in 2011 and then was UGC-BSR Faculty Fellow in the Department of Botany, Sri Krishnadevaraya University, Anantapur, India. He has published 75 books, 330 research papers, and 35 popular articles. He was the President of Indian Association for Angiosperm Taxonomy (2013) and the President of the Indian Botanical Society (2014). He has been a member of Species Survival Commission of International Union for Conservation of Nature and Natural Resources (IUCN).
Raghavendra, P.B.
Dr. P.B. Raghavendra is currently affiliated with School of Regenerative Medicine, Manipal University, Bangalore, India, and has served as Director of School of Chemical and Biological Sciences, REVA University. He is the author of Book Advances in Cell and Molecular Diagnostics and a number of articles and book chapters on various aspects of medical sciences and life sciences published in International journals. He is a visiting professor and technology consultant for many universities and biotechnology companies.
Karuppusamy, S.
Dr. S. Karuppusamy is currently affiliated with the Department of Botany, The Madura college, Madurai, India. He was Post Doctoral Fellow at Sri Krishnadevaraya University. He has published 10 books and 120 research papers. He was awarded Prof. Y.S.Murthy Gold Medal from Indian Botanical Society.
Raveendran, V.
Dr. V. Raveendran is working as Associate Scientist, Cardiovascular Research Program, King Faisal Hospital and Research Center, Riyadh, Kingdom of Saudi Arabia. He was a Post-Doctoral fellow at Department of Internal Medicine, University of Kansas Medical Center, Kansas, USA.
Anuradha, M.
Dr. M. Anuradha is currently affiliated to Padmashree Institute of Management and Sciences, Bangalore, India. She was scientist at Dr. Reddy's research foundation, Hyderabad, India and Sami Labs Pvt. Ltd. Bangalore, India. She published one book and more than 30 papers in national and international journals and co- author for book chapters. She also filed 6 Indian patents and has one US patent granted. She successfully completed four research projects on camptothecin yielding plants supported by Department of Science and Technology, New Delhi and National Medicinal Plants Board, New Delhi and consultant to private herbal companies dealing with camptothecin.
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