Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems explores the development of novel therapeutics and diagnostics to improve pulmonary disease management, looking at the nanoscale level for an efficient system of targeting and managing respiratory disease. Prevalence of chronic respiratory diseases has amplified due to an increase in pollution and decrease in air quality. A large population is affected by these respiratory diseases including individuals of all age groups incurring a high healthcare cost. This book examines numerous nanoparticle-based drug systems such as nanocrystals, dendrimers, polymeric micelles, protein-based, carbon nanotube, and liposomes that can offer advantages over traditional drug delivery systems such as improving the pharmacokinetic behavior of drug molecules entrapped in a biological entity and rapid absorption of the nanodrug due to its high surface area. Starting with a brief introduction on different types of nanoparticles in respiratory disease conditions, there is then a focus on the current trends in understanding the disease pathology using different in vitro and in vivo models, which are important toward the onsite clinical applications and developments of new therapeutics. Targeting Chronic Inflammatory Lung Diseases Using Advanced Drug Delivery Systems is designed to be useful to those new to the field and to specialized scientists and researchers involved in the pulmonary research and drug development.
- Explores the recent perspectives and challenges toward the management and diagnosis of chronic respiratory diseases related to drug delivery
- Provides insights into how advanced drug delivery systems can be effectively formulated and delivered for the management of various pulmonary diseases
- Includes the most recent information on diagnostic methods and treatment strategies using controlled drug delivery systems including nanotechnology
1. Preface 2. Introduction 3. Nanoparticles in chronic respiratory diseases 4. Targeting immune-system/ cellular level (macrophages & neutrophils) in respiratory diseases using advanced drug delivery systems 5. Mucoadhesive drug delivery system in respiratory diseases 6. Advancement in translational respiratory research using nanotechnology 7. Nanotechnology in pulmonary disease diagnosis 8. Clinical trials using in vitro and in vivo models 9. Targeting biofilms in respiratory diseases using novel drug delivery systems 10. Future prospects and challenges
Dr Kamal Dua works in the Discipline of Pharmacy at the Graduate School of Health in University of Technology Sydney, Australia.
Phil Hansbro works at the Centre for inflammation in Sydney, Australia.
Ridhima Wadhwa works in the Discipline of Pharmacy, Graduate School of Health at University of Technology Sydney, Australia.
Mehra Haghi, Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Australia
Pont, Lisa G.
Lisa G. Pont, Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Australia
Williams, Kylie A.
Kylie Williams, Discipline of Pharmacy, Graduate School of Health, University of Technology Sydney, Australia