3D Cell Cultures: Technologies and Global Markets

Summary Table: Global Market for Cell Culture, by Segment, Through 2025
Table 1: Dimensionality of Cell Culture
Table 2: WHO R&D Roadmap of Priority Infectious Diseases
Table 3: 3D Bioprinting Roadmap
Table 4: Selected Online Prices for Bioreactors
Table 5: Current Clinical Trials on Remdesivir
Table 6: Tissue Types
Table 7: Cell Types Based on Developmental Origin
Table 8: Leading Cell Line Suppliers, April 2020
Table 9: Commonly Used Transformed Cells Lines
Table 10: Major Primary Cell Lines
Table 11: Leading Primary Cell Suppliers, April 2020
Table 12: Main Types of Stem Cells
Table 13: Stem Cell Services
Table 14: Areas of Interest in 3D Spheroid Research
Table 15: Global Market for Cell Culture Consumables in Research, Through 2025
Table 16: Selected Nanoparticle Products Used in Life Science Research
Table 17: Results of Liver-Chip Drugs Halted in Previous Clinical Trials Based on Animal Studies
Table 18: Companies and Universities Involved in the Organ-on-a-Chip Industry
Table 19: Global Market for Cell Culture Equipment, by Type, Through 2025
Table 20: Microfluidics Companies
Table 21: Selected Recent Patents Issued on Microfluidic Devices Related to Cell Culture Applications
Table 22: Selected Papers Published on Recent Microfluidic Advances in Cell Culture
Table 23: High-Content Screening Suppliers and Key Attributes, April 2020
Table 24: Selected Patents Issued Related to Flow Cytometers
Table 25: Thermo Fisher Imaging Products
Table 26: Publicly Disclosed Funding of Bioprinting Companies, 2017-2020*
Table 27: Bioprinting Company Deals and Strategic Partnerships, 2019 and 2020
Table 28: Bioprinting Modalities
Table 29: Maintaining Cell Viability During Printing
Table 30: Bioprinting Instrument Industry
Table 31: Biomaterial Components
Table 32: Bioink Types
Table 33: Classes of Matrix Bioink Hydrogels
Table 34: Matrix Bioink Selection Criteria
Table 35: Selected Bioink Companies, 2020
Table 36: Projected Unit Sales of Research Bioreactors, <10 Liters, 2020
Table 37: Leading Bioreactor Suppliers, 2020
Table 38: Label-Free Technologies and Suppliers, April 2020
Table 39: Global Market for Software and Services for Cell Culture Research, Through 2025
Table 40: Global Market for Bioprocessing Consumables for Cell Culture, Through 2025
Table 41: Global Market for Cell Culture Bioprocessing Equipment, by Type, Through 2025
Table 42: Global Market for Software for Cell Culture in Bioprocessing, Through 2025
Table 43: Developmental Issues Facing the Commercialization of Exosomes
Table 44: Companies Working on Exosome Products
Table 45: Global Market for Cell Culture, by End User, Through 2025
Table 46: Global Market for Cell Culture, by Application, Through 2025
Table 47: Global Market for Cell Culture, by Region, Through 2025
Table 48: Typical Assay Endpoints and Tests
Table 49: U.S. Patents on Assays Systems, 2019 and 2020
Table 50: Selected U.S. Patents on Assay Imaging, 2019 and 2020
Table 51: Recently Issued U.S. Patents on Cellomics, 2017-2019
Table 52: Toxicology Issues That Need to Be Addressed for FDA-Regulated Products
Table 53: Overview of Federal Regulation of the Cell Culture Markets
Table 54: FDA List of Cell, Biologic and Tissue Products Regulated Under CBER and CDRH
Table 55: FDA “Talking Point” Recommendations for Regenerative Medicine Advanced Therapies (RMATs)
Table 56: U.S. Regulatory Considerations
Table 57: Main Types of Models for Researching Cancer and Other Diseases
Table 58: Goals of Funding Opportunity Announcement RFA-CA-19-055
Table 59: Common 3D Assays
Table 60: 3D Tumor Models Developed for Drug Discovery, June 2017
Table 61: Summary of the Benefits and Advantages of EV3D
Table 62: ECVAM List of Current Activities, 2020
Table 63: In Vitro Testing in Cosmetics, by Test Class
Table 64: In Vitro and In Vivo Assays in the Tier 1 Screening Battery, January 2014
Table 65: Timeline of Key Developments in Stem Cell Research, 1978-2006
Table 66: Major and Minor Research Areas in Stem Cells
Table 67: Stem Cell Usage in Research
Table 68: Recent U.S. Patents Granted on Stem Cell Technologies
Table 69: Papers Published on Selected Stem Cell Research Trends
Table 70: Comparison of the Number of Citations in the Literature on Cell Culture versus Stem Cell Culture
Table 71: Number of Organ Transplants Performed in the United States, 2018 and 2019
Table 72: Total Global Financing of Regenerative Medicine
Table 73: Total Financing of Regenerative Medicine, by Therapeutic Area
Table 74: Leading Tissue Products and Suppliers, April 2020
Table 75: Printed Tissue and Organs: Commercialization Timeframe
Table 76: Tissue/Organ Complexity
Table 77: New Bioassay Kits Introduced by BioVision
Table 78: Partial List of Specialty Media Formulations Sold by Cell Applications Inc.

Summary Figure: Global Market for Cell Culture, by Segment, 2020-2025
Figure 1: Research Chain for Cell Culture
Figure 2: A Model for The Evolution of FDA Regulation
Figure 3: An Innovation Matrix
Figure 4: Bioprinting Strategic Roadmap
Figure 5: Gastrointestinal Organotype Cultures
Figure 6: iCELLis Nanoreactor: Example of Commercial 2D Cell Culture Systems
Figure 7: Prototype of 3D Model Lung-on-a-Chip from Wake Forest
Figure 8: Recent Photos of the HepaChip
Figure 9: Recent Photos of the HepaChip-MWP
Figure 10: University of Toronto Handheld Bioprinting Device
Figure 11: Collaborative Experiment Conducted by American, Russian and Israeli Scientists
Figure 12: Smart Marbles Concept for Quantifying Process Heterogeneity
Figure 13: Porcine Intestinal Organoids
Figure 14: Diagram of the Components of a Predictive Toxicology System
Figure 15: Gleason’s Pattern
Figure 16: Diagram of PDXs, Cell Lines and Organoid/Spheroid Xenografts
Figure 17: Cell Heterogeneity and Its Function
Figure 18: Electron Micrograph of Porous Microcarrier for Stem Cell Production
Figure 19: Photograph of Apligraf