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Humanized Mice Model Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2020-2030F

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    Report

  • 180 Pages
  • November 2025
  • Region: Global
  • TechSci Research
  • ID: 5137016
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Oncology is the fastest growing segment, North America is the largest regional market

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The Global Humanized Mice Model Market, valued at USD 1.90 Billion in 2024, is projected to experience a CAGR of 10.10% to reach USD 3.38 Billion by 2030. Humanized mice models are laboratory animals engineered to carry functional human genes, cells, or tissues, thereby closely replicating human physiological and pathological conditions for research purposes. The market's expansion is primarily driven by the increasing global incidence of chronic diseases, necessitating advanced models for drug discovery and development, particularly in oncology and infectious disease research.

Key Market Drivers

The Global Humanized Mice Model Market is significantly propelled by both substantial technological advancements in genetic engineering and the increasing demand for preclinical drug development. Genetic engineering innovations, particularly advanced gene editing tools, enable the creation of highly refined humanized models that precisely mimic human physiological and pathological conditions. This precision is essential for developing more accurate preclinical tools. For example, according to the Innovative Genomics Institute (IGI), in March 2024, "CRISPR Clinical Trials: A 2024 Update", CRISPR Therapeutics initiated two phase 1 trials in 2023 targeting cardiovascular disease, directly demonstrating the application of these genetic techniques in therapeutic development.

Key Market Challenges

A substantial challenge impeding market expansion in the Global Humanized Mice Model Market is the significant cost associated with the development, maintenance, and ethical oversight of these complex models. These considerable financial requirements directly limit the accessibility and widespread adoption of humanized mice, particularly for smaller biotechnology firms, academic institutions, and emerging research initiatives that operate with more constrained budgets. The extensive investment needed for generating and sustaining these advanced research tools, alongside adherence to rigorous ethical guidelines, contributes to elevated preclinical research expenditures.

Key Market Trends

The increasing adoption of patient-derived xenograft (PDX) models is a significant trend driving the Global Humanized Mice Model Market, owing to their ability to closely mimic human tumor heterogeneity and response to therapies. These models provide a highly predictive preclinical platform essential for oncology drug development and the advancement of personalized medicine strategies. The American Association for Cancer Research (AACR), in its 2024 Cancer Progress Report, highlighted that from July 2023 to June 2024, the FDA approved several new anti-cancer therapeutics, including molecularly targeted drugs, underscoring the continuous output from intensive oncology research that relies on advanced preclinical tools.

Key Market Players Profiled:

  • Allentown LLC
  • Charles River Laboratories International, Inc.
  • HBM Holdings
  • Horizon Discovery Group plc
  • Ingenious Targeting Laboratory Inc.
  • Janvier Labs
  • Trans Genic Inc.
  • PolyGene AG
  • Aragen Life Sciences Ltd.
  • The Andersons, Inc.

Report Scope:

In this report, the Global Humanized Mice Model Market has been segmented into the following categories:

By Type:

  • Humanized Mouse Models
  • Humanized Rat Models

By Application:

  • Oncology
  • Immunology & Infectious Diseases
  • Toxicology
  • Others

By End User:

  • Pharmaceutical & Biotechnology Companies
  • Contract Research Organizations
  • Academic & Research Institutions

By Region:

  • North America
  • Europe
  • Asia-Pacific
  • South America
  • Middle East & Africa

Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the Global Humanized Mice Model Market.

Available Customizations:

With the given market data, the publisher offers customizations according to a company's specific needs. The following customization options are available for the report.

Company Information

  • Detailed analysis and profiling of additional market players (up to five).

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Table of Contents

1. Product Overview
1.1. Market Definition
1.2. Scope of the Market
1.2.1. Markets Covered
1.2.2. Years Considered for Study
1.2.3. Key Market Segmentations
2. Research Methodology
2.1. Objective of the Study
2.2. Baseline Methodology
2.3. Key Industry Partners
2.4. Major Association and Secondary Sources
2.5. Forecasting Methodology
2.6. Data Triangulation & Validation
2.7. Assumptions and Limitations
3. Executive Summary
3.1. Overview of the Market
3.2. Overview of Key Market Segmentations
3.3. Overview of Key Market Players
3.4. Overview of Key Regions/Countries
3.5. Overview of Market Drivers, Challenges, Trends
4. Voice of Customer
5. Global Humanized Mice Model Market Outlook
5.1. Market Size & Forecast
5.1.1. By Value
5.2. Market Share & Forecast
5.2.1. By Type (Humanized Mouse Models, Humanized Rat Models)
5.2.2. By Application (Oncology, Immunology & Infectious Diseases, Toxicology, Others)
5.2.3. By End User (Pharmaceutical & Biotechnology Companies, Contract Research Organizations, Academic & Research Institutions)
5.2.4. By Region
5.2.5. By Company (2024)
5.3. Market Map
6. North America Humanized Mice Model Market Outlook
6.1. Market Size & Forecast
6.1.1. By Value
6.2. Market Share & Forecast
6.2.1. By Type
6.2.2. By Application
6.2.3. By End User
6.2.4. By Country
6.3. North America: Country Analysis
6.3.1. United States Humanized Mice Model Market Outlook
6.3.1.1. Market Size & Forecast
6.3.1.1.1. By Value
6.3.1.2. Market Share & Forecast
6.3.1.2.1. By Type
6.3.1.2.2. By Application
6.3.1.2.3. By End User
6.3.2. Canada Humanized Mice Model Market Outlook
6.3.2.1. Market Size & Forecast
6.3.2.1.1. By Value
6.3.2.2. Market Share & Forecast
6.3.2.2.1. By Type
6.3.2.2.2. By Application
6.3.2.2.3. By End User
6.3.3. Mexico Humanized Mice Model Market Outlook
6.3.3.1. Market Size & Forecast
6.3.3.1.1. By Value
6.3.3.2. Market Share & Forecast
6.3.3.2.1. By Type
6.3.3.2.2. By Application
6.3.3.2.3. By End User
7. Europe Humanized Mice Model Market Outlook
7.1. Market Size & Forecast
7.1.1. By Value
7.2. Market Share & Forecast
7.2.1. By Type
7.2.2. By Application
7.2.3. By End User
7.2.4. By Country
7.3. Europe: Country Analysis
7.3.1. Germany Humanized Mice Model Market Outlook
7.3.1.1. Market Size & Forecast
7.3.1.1.1. By Value
7.3.1.2. Market Share & Forecast
7.3.1.2.1. By Type
7.3.1.2.2. By Application
7.3.1.2.3. By End User
7.3.2. France Humanized Mice Model Market Outlook
7.3.2.1. Market Size & Forecast
7.3.2.1.1. By Value
7.3.2.2. Market Share & Forecast
7.3.2.2.1. By Type
7.3.2.2.2. By Application
7.3.2.2.3. By End User
7.3.3. United Kingdom Humanized Mice Model Market Outlook
7.3.3.1. Market Size & Forecast
7.3.3.1.1. By Value
7.3.3.2. Market Share & Forecast
7.3.3.2.1. By Type
7.3.3.2.2. By Application
7.3.3.2.3. By End User
7.3.4. Italy Humanized Mice Model Market Outlook
7.3.4.1. Market Size & Forecast
7.3.4.1.1. By Value
7.3.4.2. Market Share & Forecast
7.3.4.2.1. By Type
7.3.4.2.2. By Application
7.3.4.2.3. By End User
7.3.5. Spain Humanized Mice Model Market Outlook
7.3.5.1. Market Size & Forecast
7.3.5.1.1. By Value
7.3.5.2. Market Share & Forecast
7.3.5.2.1. By Type
7.3.5.2.2. By Application
7.3.5.2.3. By End User
8. Asia-Pacific Humanized Mice Model Market Outlook
8.1. Market Size & Forecast
8.1.1. By Value
8.2. Market Share & Forecast
8.2.1. By Type
8.2.2. By Application
8.2.3. By End User
8.2.4. By Country
8.3. Asia-Pacific: Country Analysis
8.3.1. China Humanized Mice Model Market Outlook
8.3.1.1. Market Size & Forecast
8.3.1.1.1. By Value
8.3.1.2. Market Share & Forecast
8.3.1.2.1. By Type
8.3.1.2.2. By Application
8.3.1.2.3. By End User
8.3.2. India Humanized Mice Model Market Outlook
8.3.2.1. Market Size & Forecast
8.3.2.1.1. By Value
8.3.2.2. Market Share & Forecast
8.3.2.2.1. By Type
8.3.2.2.2. By Application
8.3.2.2.3. By End User
8.3.3. Japan Humanized Mice Model Market Outlook
8.3.3.1. Market Size & Forecast
8.3.3.1.1. By Value
8.3.3.2. Market Share & Forecast
8.3.3.2.1. By Type
8.3.3.2.2. By Application
8.3.3.2.3. By End User
8.3.4. South Korea Humanized Mice Model Market Outlook
8.3.4.1. Market Size & Forecast
8.3.4.1.1. By Value
8.3.4.2. Market Share & Forecast
8.3.4.2.1. By Type
8.3.4.2.2. By Application
8.3.4.2.3. By End User
8.3.5. Australia Humanized Mice Model Market Outlook
8.3.5.1. Market Size & Forecast
8.3.5.1.1. By Value
8.3.5.2. Market Share & Forecast
8.3.5.2.1. By Type
8.3.5.2.2. By Application
8.3.5.2.3. By End User
9. Middle East & Africa Humanized Mice Model Market Outlook
9.1. Market Size & Forecast
9.1.1. By Value
9.2. Market Share & Forecast
9.2.1. By Type
9.2.2. By Application
9.2.3. By End User
9.2.4. By Country
9.3. Middle East & Africa: Country Analysis
9.3.1. Saudi Arabia Humanized Mice Model Market Outlook
9.3.1.1. Market Size & Forecast
9.3.1.1.1. By Value
9.3.1.2. Market Share & Forecast
9.3.1.2.1. By Type
9.3.1.2.2. By Application
9.3.1.2.3. By End User
9.3.2. UAE Humanized Mice Model Market Outlook
9.3.2.1. Market Size & Forecast
9.3.2.1.1. By Value
9.3.2.2. Market Share & Forecast
9.3.2.2.1. By Type
9.3.2.2.2. By Application
9.3.2.2.3. By End User
9.3.3. South Africa Humanized Mice Model Market Outlook
9.3.3.1. Market Size & Forecast
9.3.3.1.1. By Value
9.3.3.2. Market Share & Forecast
9.3.3.2.1. By Type
9.3.3.2.2. By Application
9.3.3.2.3. By End User
10. South America Humanized Mice Model Market Outlook
10.1. Market Size & Forecast
10.1.1. By Value
10.2. Market Share & Forecast
10.2.1. By Type
10.2.2. By Application
10.2.3. By End User
10.2.4. By Country
10.3. South America: Country Analysis
10.3.1. Brazil Humanized Mice Model Market Outlook
10.3.1.1. Market Size & Forecast
10.3.1.1.1. By Value
10.3.1.2. Market Share & Forecast
10.3.1.2.1. By Type
10.3.1.2.2. By Application
10.3.1.2.3. By End User
10.3.2. Colombia Humanized Mice Model Market Outlook
10.3.2.1. Market Size & Forecast
10.3.2.1.1. By Value
10.3.2.2. Market Share & Forecast
10.3.2.2.1. By Type
10.3.2.2.2. By Application
10.3.2.2.3. By End User
10.3.3. Argentina Humanized Mice Model Market Outlook
10.3.3.1. Market Size & Forecast
10.3.3.1.1. By Value
10.3.3.2. Market Share & Forecast
10.3.3.2.1. By Type
10.3.3.2.2. By Application
10.3.3.2.3. By End User
11. Market Dynamics
11.1. Drivers
11.2. Challenges
12. Market Trends & Developments
12.1. Merger & Acquisition (If Any)
12.2. Product Launches (If Any)
12.3. Recent Developments
13. Global Humanized Mice Model Market: SWOT Analysis
14. Porter's Five Forces Analysis
14.1. Competition in the Industry
14.2. Potential of New Entrants
14.3. Power of Suppliers
14.4. Power of Customers
14.5. Threat of Substitute Products
15. Competitive Landscape
15.1. Allentown LLC
15.1.1. Business Overview
15.1.2. Products & Services
15.1.3. Recent Developments
15.1.4. Key Personnel
15.1.5. SWOT Analysis
15.2. Charles River Laboratories International, Inc.
15.3. HBM Holdings
15.4. Horizon Discovery Group plc
15.5. Ingenious Targeting Laboratory Inc.
15.6. Janvier Labs
15.7. Trans Genic Inc.
15.8. PolyGene AG
15.9. Aragen Life Sciences Ltd.
15.10. the Andersons, Inc.
16. Strategic Recommendations17. About the Publisher & Disclaimer

Companies Mentioned

The companies profiled in this Humanized Mice Model market report include:
  • Allentown LLC
  • Charles River Laboratories International, Inc.
  • HBM Holdings
  • Horizon Discovery Group plc
  • Ingenious Targeting Laboratory Inc.
  • Janvier Labs
  • Trans Genic Inc.
  • PolyGene AG
  • Aragen Life Sciences Ltd.
  • The Andersons, Inc.

Table Information