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Tailor-Made Polysaccharides in Drug Delivery

  • Book

  • September 2022
  • Elsevier Science and Technology
  • ID: 5137673

Tailor-Made Polysaccharides in Drug Delivery provides extensive details on all the vital precepts, basics and fundamental aspects of tailored polysaccharides in the pharmaceutical and biotechnological industry for understanding and developing high quality products. The book offers a comprehensive resource to understand the potential of the materials in forming new drug delivery methods. It will be useful to pharmaceutical scientists, chemical engineers, and regulatory scientists and students actively involved in pharmaceutical product and process development of tailored-made polysaccharides in drug delivery applications.

The utilization of natural polymeric excipients in numerous healthcare applications demand the replacement of the synthetic polymers with the natural ones due to their biocompatibility, biodegradability, economic extraction and readily availability. The reality behind the rise in importance of these natural materials is that these sources are renewable if grown in a sustainable means and they can tender incessant supply of raw materials. Amongst these natural polymers, polysaccharides are considered as excellent excipients because of its non-toxic, stable, biodegradable properties. Several research innovations have been made on applications of polysaccharides in drug delivery.

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Table of Contents

1. Synthesis of tailor-made polysaccharides: An overview
2. Drug delivery dosage forms made of tailor-made natural polysaccharides
3. Carboxymethylated polysaccharides in drug delivery
4. Thiolated polysaccharides in drug delivery
5. Cross-linked polysaccharides in drug delivery
6. Graft copolymers of polysaccharides: Synthesis techniques and pharmaceutical applications
7. Grafted polysaccharides in drug delivery
8. Polysaccharide-based polyelectrolyte complex systems in drug delivery
9. Polysaccharide-based interpenetrating polymeric network systems in drug delivery
10. Polysaccharide nanoconjugates in drug delivery
11. Functionalized chitosan in drug delivery
12. Modified alginates in drug delivery
13. Uses of tailor-made plant starches in drug delivery
14. Cancer targeting by tailor-made polysaccharides
15. Delivery of gene and growth factors using tailor-made polysaccharides


Amit Kumar Nayak Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India.

Dr. Amit Kumar Nayak (MPharm, PhD) is working as a professor, at the Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to be University), Odisha, India. He has earned his PhD from IFTM University, Moradabad, Uttar Pradesh, India. He has over 14 years of research experiences in the field of pharmaceutics, especially in the development and characterization of novel biopolymeric and nanostructured drug delivery systems. Till date, he has authored more than 138 research and review publications in various high-impact peer-reviewed journals and 135 book chapters. He has edited/authored 23 international books to his credit. Dr. Nayak has presented his research work at several conferences. He has received University Foundation Day Research Award, 2019 and 2022 by Biju Patnaik University of Technology, Odisha. Dr. Nayak is a life member of the Association of Pharmaceutical Teachers of India (APTI) and a registered pharmacist.

Md Saquib Hasnain Department of Pharmacy, Palamau Institute of Pharmacy, Daltonganj, Jharkhand, India. Prof. (Dr.) Md Saquib Hasnain has over 10 years of research experience in the field of drug delivery and pharmaceutical formulation analyses, especially systematic development and characterization of diverse nanostructured drug delivery systems, controlled release drug delivery systems, bioenhanced drug delivery systems, nanomaterials and nanocomposites employing Quality by Design approaches and many more. Till date he has authored over 70 publications in various high impact peer-reviewed journals, more than 100 book chapters and 16 books to his credit. He is also serving as the reviewer of several prestigious journals. Overall, he has earned a highly impressive publishing and cited record in Google Scholar (h-index: 32). He has also participated and presented his research work at over ten conferences in India, and abroad. He was also a member of scientific societies i.e., Royal Society of Chemistry, Great Britain, International Association of Environmental and Analytical Chemistry, Switzerland and Swiss Chemical Society, Switzerland.