Tailor-Made Polysaccharides in Drug Delivery provides extensive details on all the vital precepts, basics and fundamental aspects of tailored polysaccharides in the pharmaceutical and biotechnological industry for understanding and developing high quality products. The book offers a comprehensive resource to understand the potential of the materials in forming new drug delivery methods. It will be useful to pharmaceutical scientists, chemical engineers, and regulatory scientists and students actively involved in pharmaceutical product and process development of tailored-made polysaccharides in drug delivery applications.
The utilization of natural polymeric excipients in numerous healthcare applications demand the replacement of the synthetic polymers with the natural ones due to their biocompatibility, biodegradability, economic extraction and readily availability. The reality behind the rise in importance of these natural materials is that these sources are renewable if grown in a sustainable means and they can tender incessant supply of raw materials. Amongst these natural polymers, polysaccharides are considered as excellent excipients because of its non-toxic, stable, biodegradable properties. Several research innovations have been made on applications of polysaccharides in drug delivery.
- Provides methodologies for the design, development and selection of tailor-made, natural polysaccharides in drug delivery for particular therapeutic applications
- Includes illustrations that demonstrate the mechanism of biological interaction of tailor-made polysaccharides
- Discusses the regulatory aspects and demonstrates the clinical efficacy of tailor-made polysaccharides
1. Synthesis of tailor-made polysaccharides: An overview 2. Carboxymethylated polysaccharides in drug delivery 3. Thiolated polysaccharides in drug delivery 4. Esterified polysaccharides in drug delivery 5. Cross-linked polysaccharides in drug delivery 6. Grafted polysaccharides in drug delivery 7. Polysaccharide-based interpenetrating polymeric network systems in drug delivery 8. Polysaccharide-based polyelectrolyte complex systems in drug delivery 9. Modified alginates in drug delivery 10. Modified chitosan in drug delivery 11. Tailored plant gums and mucilages in drug delivery 12. Uses of tailor-made plant starches in drug delivery 13. Cancer targeting by using? tailor-made polysaccharides 14. Delivery of gene and growth factors using tailor-made polysaccharides
Amit Kumar Nayak, PhD, is currently working as Associate Professor at Seemanta Institute of Pharmaceutical Sciences, Odisha, India. He has earned his PhD in Pharmaceutical Sciences from IFTM University, Moradabad, U.P., India. He has over 10 years of research experience in the field of pharmaceutics, especially in the development and characterization of polymeric composites, hydrogels, novel and nanostructured drug delivery systems. Till date, he has authored over 120 publications in various high impact peer-reviewed journals and 72 book chapters to his credit. He has been the permanent reviewer of many international journals of high repute. He also has participated and presented his research work at several conferences in India and is a life member of Association of Pharmaceutical Teachers of India (APTI).
Hasnain, Md Saquib
Dr. Md Saquib Hasnain has over 6 years of research experience in the field of drug delivery and pharmaceutical formulation and analyses; especially systematic development and characterization of diverse nanostructured drug delivery systems, controlled release drug delivery systems, bioenhanced drug delivery systems, polymeric composites, nanomaterials and nanocomposites employing Quality by Design approaches. Till date he has authored over 30 publications in various high impact peer-reviewed journals, around 30 book chapters, 1 Indian patent application and 4 books to his credit. He is also serving as the reviewer of several prestigious journals. He is also serving as the associate editorial board member of Recent Patent on Drug Delivery & Formulation journal. Overall, he has earned highly impressive publishing and cited record in Google Scholar (H-Index: 12). He has also participated and presented his research work at over ten conferences in India, and abroad. He is also the member of scientific societies, i.e., Royal Society of Chemistry, Great Britain, International Association of Environmental and Analytical Chemistry, Switzerland and Swiss Chemical Society, Switzerland.