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Highlights
Cardiff Oncology Inc (Cardiff) is a clinical-stage biotechnology company focused on developing novel cancer therapies. The company's main activity involves leveraging PLK1 inhibition to create treatments for various cancers with significant unmet medical needs. Its major product is onvansertib, an oral and highly selective PLK1 inhibitor, which is being developed in combination with standard-of-care therapeutics. Cardiff is advancing various clinical trials, including the Phase 2 CRDF-004 trial for first-line RAS-mutated metastatic colorectal cancer (mCRC) and the TROV-054 trial for second-line KRAS-mutated mCRC. The company utilizes tumor genomics and biomarker assays to enhance patient response assessments. It is also investigating onvansertib for metastatic pancreatic ductal adenocarcinoma, small cell lung cancer, and triple-negative breast cancer, exploring various combination therapies. Cardiff is headquartered in San Diego, California, the US.Cardiff Oncology Inc Key Recent Developments
- Dec 08, 2025: Cardiff Oncology To Present At Sidoti Year-End Virtual Investor Conference
- Nov 06, 2025: Cardiff Oncology Reports Third Quarter 2025 Results and Business Update
- Jun 17, 2025: Cardiff Oncology Appoints Dr. Roger Sidhu as Chief Medical Officer and Announces Timing for the Next Update from the CRDF-004 Trial in First-Line RAS-mutated mCRC
- May 08, 2025: Cardiff Oncology Reports First Quarter 2025 Results and Provides Business Update
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Table of Contents
Companies Mentioned (Partial List)
A selection of companies mentioned in this report includes, but is not limited to:
- Boehringer Ingelheim International GmbH
- Jazz Pharmaceuticals Plc
- Genetix Biotherapeutics Inc
- Bio Green Med Solution Inc
- Coherus Oncology Inc

