Fragment-based Drug Discovery - Global Strategic Business Report

The global market for Fragment-based Drug Discovery was estimated at US$977.0 Million in 2024 and is projected to reach US$1.6 Billion by 2030, growing at a CAGR of 8.8% from 2024 to 2030. This comprehensive report provides an in-depth analysis of market trends, drivers, and forecasts, helping you make informed business decisions. The report includes the most recent global tariff developments and how they impact the Fragment-based Drug Discovery market.

Global Fragment-Based Drug Discovery Market - Key Trends & Drivers Summarized

Why Is Fragment-Based Drug Discovery a Game Changer in Pharmaceuticals?

Fragment-Based Drug Discovery (FBDD) has revolutionized pharmaceutical research by allowing scientists to develop drugs with higher specificity and efficacy. Unlike traditional drug discovery, FBDD involves screening smaller, “fragment” molecules that bind to target sites on proteins, which can then be optimized into potent drugs. This approach is particularly effective for complex disease targets such as cancer, where traditional methods have struggled. FBDD accelerates the drug discovery process and often leads to more viable drug candidates, making it a valuable approach for addressing unmet medical needs.

How Are Advanced Screening Techniques Enhancing FBDD?

The success of FBDD heavily relies on advanced screening technologies that enable the identification of fragment interactions with target proteins. Techniques like nuclear magnetic resonance (NMR), X-ray crystallography, and high-throughput screening allow researchers to visualize binding interactions in detail, facilitating more precise drug design. Recent advancements in AI-driven screening and computational modeling further optimize the FBDD process by predicting fragment-target binding more accurately. These innovations make FBDD a faster, more efficient, and cost-effective approach to drug discovery, appealing to pharmaceutical companies aiming for shorter development timelines.

What Role Does FBDD Play in Cancer and Neurological Research?

FBDD is particularly valuable in oncology and neurological research, where complex and traditionally “undruggable” targets are common. Cancer research, for example, benefits from FBDD’s ability to identify small molecule inhibitors that can precisely target and disrupt cancer cell growth mechanisms. Similarly, in neurological disorders, FBDD aids in discovering treatments that can cross the blood-brain barrier, addressing diseases like Alzheimer’s and Parkinson’s. The ability of FBDD to uncover novel therapeutic options for difficult-to-treat conditions makes it a growing area of focus in medical research.

What Drives Growth in the Fragment-Based Drug Discovery Market?

The growth in the FBDD market is driven by advancements in screening technologies, rising demand for targeted therapies, and its applications in challenging disease areas. New screening tools and AI-driven computational models enhance the efficiency of FBDD, attracting pharmaceutical companies looking for cost-effective drug discovery methods. The demand for targeted therapies, especially in oncology and neurology, further fuels FBDD adoption. Moreover, FBDD’s ability to identify novel treatment options for complex diseases provides a pathway for addressing unmet medical needs, making it a crucial area in modern pharmaceutical research.

SCOPE OF STUDY:

The report analyzes the Fragment-based Drug Discovery market in terms of units by the following Segments, and Geographic Regions/Countries:

• Segments: Technology (Fragment Screening, Fragment Optimization); End-Use (Biopharmaceutical Companies, Academic & Research Institutions, Contract Research Organizations)
• Geographic Regions/Countries: World; United States; Canada; Japan; China; Europe (France; Germany; Italy; United Kingdom; and Rest of Europe); Asia-Pacific; Rest of World.

Key Insights:

• Market Growth: Understand the significant growth trajectory of the Fragment Screening segment, which is expected to reach US$1.1 Billion by 2030 with a CAGR of a 9.9%. The Fragment Optimization segment is also set to grow at 7.0% CAGR over the analysis period.
• Regional Analysis: Gain insights into the U.S. market, valued at $270.8 Million in 2024, and China, forecasted to grow at an impressive 8.2% CAGR to reach $248.7 Million by 2030. Discover growth trends in other key regions, including Japan, Canada, Germany, and the Asia-Pacific.

Why You Should Buy This Report:

• Detailed Market Analysis: Access a thorough analysis of the Global Fragment-based Drug Discovery Market, covering all major geographic regions and market segments.
• Competitive Insights: Get an overview of the competitive landscape, including the market presence of major players across different geographies.
• Future Trends and Drivers: Understand the key trends and drivers shaping the future of the Global Fragment-based Drug Discovery Market.
• Actionable Insights: Benefit from actionable insights that can help you identify new revenue opportunities and make strategic business decisions.

Key Questions Answered:

• How is the Global Fragment-based Drug Discovery Market expected to evolve by 2030?
• What are the main drivers and restraints affecting the market?
• Which market segments will grow the most over the forecast period?
• How will market shares for different regions and segments change by 2030?
• Who are the leading players in the market, and what are their prospects?

Report Features:

• Comprehensive Market Data: Independent analysis of annual sales and market forecasts in US$ Million from 2024 to 2030.
• In-Depth Regional Analysis: Detailed insights into key markets, including the U.S., China, Japan, Canada, Europe, Asia-Pacific, Latin America, Middle East, and Africa.
• Company Profiles: Coverage of players such as Akaal Pharma Pty. Ltd., Algorae Pharmaceuticals Ltd., Aragen Life Sciences Ltd., Beactica Therapeutics AB, Carna Biosciences, Inc. and more.
• Complimentary Updates: Receive free report updates for one year to keep you informed of the latest market developments.

Some of the 44 companies featured in this Fragment-based Drug Discovery market report include:

• Akaal Pharma Pty. Ltd.
• Algorae Pharmaceuticals Ltd.
• Aragen Life Sciences Ltd.
• Beactica Therapeutics AB
• Carna Biosciences, Inc.
• Charles River Laboratories International, Inc.
• Crelux
• Evotec SE
• Marsala Biotech Inc.
• PsychoGenics, Inc.

This edition integrates the latest global trade and economic shifts as of June 2025 into comprehensive market analysis. Key updates include:

• Tariff and Trade Impact: Insights into global tariff negotiations across 180+ countries, with analysis of supply chain turbulence, sourcing disruptions, and geographic realignment. Special focus on 2025 as a pivotal year for trade tensions, including updated perspectives on the Trump-era tariffs.
• Adjusted Forecasts and Analytics: Revised global and regional market forecasts through 2030, incorporating tariff effects, economic uncertainty, and structural changes in globalization. Includes segmentation by product, technology, type, material, distribution channel, application, and end-use, with historical analysis since 2015.
• Strategic Market Dynamics: Evaluation of revised market prospects, regional outlooks, and key economic indicators such as population and urbanization trends.
• Innovation & Technology Trends: Latest developments in product and process innovation, emerging technologies, and key industry drivers shaping the competitive landscape.
• Competitive Intelligence: Updated global market share estimates for 2025, competitive positioning of major players (Strong/Active/Niche/Trivial), and refined focus on leading global brands and core players.
• Expert Insight & Commentary: Strategic analysis from economists, trade experts, and domain specialists to contextualize market shifts and identify emerging opportunities.
• Complimentary Update: Buyers receive a free July 2025 update with finalized tariff impacts, new trade agreement effects, revised projections, and expanded country-level coverage.