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Advances in CRISPR/Cas and Related Technologies, Vol 178. Progress in Molecular Biology and Translational Science

  • ID: 5146448
  • Book
  • March 2021
  • 300 Pages
  • Elsevier Science and Technology
Advances in CRISPR/Cas and related technologies, Volume 179, the latest release in this ongoing series, deals with a wide variety of research topics related to recent advancement in the genome editing techniques. Associated chapters in this new release include Challenges for Therapeutic application of CRISPR Cas techniques, Mitochondrial DNA modification by CRISPR Cas System: Challenges and future direction, Trends in CRISPR Cas technology application in cancer, Modified CRISPR-Cas for next generation application, Application of CRISPR Cas in Synthetic Biology: Challenges and Scopes, History of CRISPR Cas system from bacterial Adaptive Immune System to research application, and more.
  • Covers the Cas9 protein modification for reduced off-target effect
  • Includes discussions on Cas9 utilization for Metabolic Engineering
  • Provides information on the use of Cas9 for targeted delivery in therapeutic application
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Preface Dipanjan Ghosh 1. Challenges for Therapeutic application of CRISPR Cas techniques Sobhan Roy 2. Mitochondrial DNA modification by CRISPR Cas System: Challenges and future direction Anbarasu K 3. Trends in CRISPR Cas technology application in cancer Sujit K. Bhutia 4. Modified CRISPR-Cas for next generation application Munsi Azad Hossain 5. Application of CRISPR Cas in Synthetic Biology: Challenges and Scopes Guhan Jayaraman 6. History of CRISPR Cas system from bacterial Adaptive Immune System to research application Sivaprakash Ramalingam 7. Use of CRISPR Cas System for quick Diagnosis Kristie Jenkins 8. New Delivery System of CRISPR Cas for better efficacy Brian Rabinovich 9. Modification of CRISPR Cas component to reduce off target effect Dipanjan Ghosh
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Ghosh, Dipanjan
Dr. Dipanjan Ghosh has almost 19 years of research experience in the field of Molecular Biology, Cell Biology, Biochemistry, Immunology and genome editing. Presently Dr. Ghosh is working as Assistant Professor in the Department of Natural Products at National Institute of Pharmaceutical Education and Research (NIPER)-Kolkata. After getting MSc. in Biochemistry from University of Calcutta, Dr. Ghosh went to Indian Institute of Technology (IIT) Kharagpur where he did his MTech in Biotechnology and Bioprocess Engineering and then PhD in the field of Immunology, Cancer Biology Biochemistry. In his first postdoc at University of Texas Health Science Centre at Houston he worked in the field of catalytic enzyme. He then moved to UT MD Anderson Cancer Centre, Houston TX where he gained enough experience in field of genome editing using ZFN and CRISPR Cas systems. Dr. Ghosh received DST FAST TRACK YOUNG SCIENTIST GRANT from Department of Science and Technology, India. Presently he has initiated Synthetic Biology through metabolic bioengineering at his lab and acting as leading investigator of two major funded projects (one from DBT and another one from WBDBT) in the field of CRISPR Cas mediated genome editing.
Dr. Ghosh has enough experience, skill, knowledge and publication in the field of genome editing.
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