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Recent Advances in iPSCs for Therapy. Advances in Stem Cell Biology

  • ID: 5146469
  • Book
  • February 2021
  • Elsevier Science and Technology

The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. Recent Advances in iPSCs for Therapy, Volume 3 addresses the use of induced pluripotent stem cells for therapy of several disorders.

The volume teaches the reader about the biology of induced pluripotent stem cells and their possible use as cell therapy. Remarkable progress has been made in the obtention of induced pluripotent stem cells and their differentiation into several cell types, tissues and organs using state-of-art techniques.

This volume will cover what we know so far about the use of iPSCs for therapy of multiple diseases, such as: hair loss disorders, Parkinson's disease, Huntington's disease, ischemic stroke, Alzheimer's disease, Glaucoma, Optic Neuropathy, Age-Related Macular Degeneration, Type 1 Diabetes, Heart Failure, liver diseases, infertility, Autoimmune Diseases, and more.

The volume is written for researchers and scientists interested in cell therapy, stem cell biology, regenerative medicine, and organ transplantation and is contributed by world-renowned authors in the field.

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1. Strategies to Utilize iPS Cells for Hair Follicle Regeneration and the Treatment of Hair Loss Disorders 2. iPSCs and Cell Therapy for Parkinson's Disease 3. Induced Pluripotent Stem Cells as a Potential Treatment for Huntington's Disease 4. Present and Future of Adult Stem Cells and Induced Pluripotent Stem Cells Therapy for Ischemic Stroke 5. Stem Cell Therapy in Alzheimer's Disease 6. Stem Cell Therapies for Glaucoma and Optic Neuropathy 7. Induced Pluripotent Stem Cells (iPSC) In Age-Related Macular Degeneration (AMD) 8. Considerations in Using Human Pluripotent Stem Cell-Derived Pancreatic Beta Cells to Treat Type 1 Diabetes 9. Induced Pluripotent Stem Cells for Treatment of Heart Failure 10. Induced Pluripotent Stem Cells in Liver Disease 11. Induced Pluripotent Stem Cells: Potential Therapeutic Application for Improving Fertility in Humans and Animals 12. Induced Pluripotent Stem Cells in Wound Healing 13. Induced Pluripotent Stem Cells for Periodontal Regeneration 14. Current Development in Ipscs-based Therapy for Autoimmune Diseases

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Alexander Birbrair Department of Pathology, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil
Department of Radiology, Columbia University Medical Center, Medical Center, USA. Dr. Alexander Birbrair received his bachelor's biomedical degree from Santa Cruz State University in Brazil. He completed his PhD in Neuroscience, in the field of stem cell biology, at the Wake Forest School of Medicine under the mentorship of Osvaldo Delbono. Then, he joined as a postdoc in stem cell biology at Paul Frenette's laboratory at Albert Einstein School of Medicine in New York. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. His research is funded by the Serrapilheira Institute, CNPq, CAPES, and FAPEMIG. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC), and, in 2019, he was elected member of the Global Young Academy (GYA), and in 2021, he was elected affiliate member of The World Academy of Sciences (TWAS). He is the Founding Editor and Editor-in-Chief of Current Tissue Microenvironment Reports, and Associate Editor of Molecular Biotechnology. Alexander also serves in the editorial board of several other international journals: Stem Cell Reviews and Reports, Stem Cell Research, Stem Cells and Development, and Histology and Histopathology.
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