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Oligonucleotide Synthesis Market - Growth, Trends, and Forecast (2020 - 2025)

  • ID: 5176069
  • Report
  • October 2020
  • Region: Global
  • 117 Pages
  • Mordor Intelligence
until Sep 30th 2021


  • Agilent Technologies
  • Bio-Synthesis Inc.
  • Danaher Corporation
  • Eurofins Scientific
  • GenScript
  • Merck KGaA
  • MORE
The oligonucleotide synthesis market is expected to register a CAGR of 12.3% during the forecast period. The growth of the oligonucleotide synthesis market is due to the increasing government investments and R&D expenditure in pharmaceutical and biotechnology companies and the use of synthesized oligonucleotides in molecular diagnostics and clinical applications.
  • The usage of synthetic oligonucleotides has been increasing rapidly over the past decade, owing to several benefits offered by molecular diagnostics and growing clinical applications. The nucleic acid application techniques are the reference methods, and they are very useful for carrying out the molecular diagnosis in several diseases, like for the detection of infectious diseases, such as hepatitis.
  • Synthetic oligonucleotides also have significant clinical applications, primarily for the detection of autoimmune antibodies. There have been consistent developments in synthetic biology over the past few years, where synthetic oligonucleotides were used to develop assays for the detection of anti-double-stranded DNAs. Thus, all these factors are responsible for the growth of the oligonucleotide synthesis market.
  • In addition, there are also other major factors influencing the market for oligonucleotide synthesis. These include the increasing advancement in the field of healthcare, increasing demand for innovation in the field of life science and medical academics, increasing investments by the government for the development of genomic technologies, and the increasing demand for oligonucleotide synthesis technologies by the public and private research firms.
Key Market Trends

The Probes Segment is Expected to Grow during the Forecast Period

Oligonucleotide probes are short stretches of single-stranded DNA or RNA, primarily used to detect the presence of complementary nucleic acid sequences (target sequences) by hybridization.

They have wide applications in the life sciences industry. They are frequently used in the polymerization chain reaction (PCR) technique. In the real-time PCR technique, the DNA amount, if increased, can be observed and detected directly in real-time. This direct observation for quantification has raised new applications, particularly in diagnostics and validation, and is attained by using fluorescent dyes.

There are several types of probes, such as dual-labeled probes, double-quenched probes, fret probes, gene probes, etc. All of them have almost similar functions but are used for different applications.

North America is the Largest Growing Segment and is Expected to Follow the Same Trend Over the Forecast Period

North America dominates the market due to the presence of better healthcare infrastructure and the increasing usage of oligonucleotides by pharmaceutical companies in the region. Furthermore, the strong foothold of North America in genomics, proteomics, oncology, diagnostic screening, and drug discovery has significantly contributed to maintaining its large share. In the region, the United States is leading the market and is expected to continue the same over the forecast period.

Competitive Landscape

The companies are seen adopting various strategies that include the acquisition of players in the emerging markets, distribution partnerships, and collaboration for the development of novel technologies. The companies operating in the oligonucleotide synthesis industry are also expanding and developing their product portfolios, which helps to drive the overall market.

Reasons to Purchase this report:
  • The market estimate (ME) sheet in Excel format
  • 3 months of analyst support
Note: Product cover images may vary from those shown


  • Agilent Technologies
  • Bio-Synthesis Inc.
  • Danaher Corporation
  • Eurofins Scientific
  • GenScript
  • Merck KGaA
  • MORE
1.1 Study Assumptions
1.2 Scope of the Study



4.1 Market Overview
4.2 Market Drivers
4.2.1 Increasing Government Investments and R&D Expenditure in Pharmaceutical and Biotechnology Companies
4.2.2 The Use of Synthesized Oligonucleotides in Molecular Diagnostics and Clinical Applications
4.3 Market Restraints
4.3.1 High Treatment Cost of Oligonucleotides
4.3.2 Lack of Skilled Professionals and Research Support in Undeveloped Countries
4.4 Porter's Five Forces Analysis
4.4.1 Threat of New Entrants
4.4.2 Bargaining Power of Buyers/Consumers
4.4.3 Bargaining Power of Suppliers
4.4.4 Threat of Substitute Products
4.4.5 Intensity of Competitive Rivalry

5.1 By Product Type
5.1.1 Synthesized Oligonucleotide Products
5.1.2 Reagents
5.1.3 Equipment
5.1.4 Services
5.2 By Application
5.2.1 Research
5.2.2 Diagnostics
5.2.3 Therapeutics
5.3 By End User
5.3.1 Academic Research Institutes
5.3.2 Pharmaceutical and Biotechnology Companies
5.3.3 Hospital and Diagnostic Laboratories
5.4 Geography
5.4.1 North America United States Canada Mexico
5.4.2 Europe Germany United Kingdom France Italy Spain Rest of Europe
5.4.3 Asia-Pacific China Japan India Australia South Korea Rest of Asia-Pacific
5.4.4 Middle-East and Africa GCC South Africa Rest of Middle-East and Africa
5.4.5 South America Brazil Argentina Rest of South America

6.1 Company Profiles
6.1.1 Agilent Technologies
6.1.2 Thermo Fisher Scientific
6.1.3 Merck KGaA
6.1.4 Danaher Corporation
6.1.5 Bio-Synthesis Inc.
6.1.6 Eurofins Scientific
6.1.7 Kaneka Corporation (Eurogentec)
6.1.8 GenScript
6.1.9 LGC Limited (LGC Biosearch Technologies)

Note: Product cover images may vary from those shown

A selection of companies mentioned in this report includes:

  • Agilent Technologies
  • Thermo Fisher Scientific
  • Merck KGaA
  • Danaher Corporation
  • Bio-Synthesis Inc.
  • Eurofins Scientific
  • Kaneka Corporation (Eurogentec)
  • GenScript
  • LGC Limited (LGC Biosearch Technologies)
Note: Product cover images may vary from those shown