Osseoconductive Surface Engineering for Orthopedic Implants: Biomaterials Engineering provides a comprehensive overview on the state-of-the-art of osseointegration based on surface-mediating coatings. Each chapter delves into both engineering and clinical aspects of processing these bioactive coatings, including their characteristics and history of process technology to aid process selection, as well as a balanced overview of resultant implant osseointegration and therefore clinical application. This book provides a practical approach to design and development of implant coatings by reviewing and discussing the usability and efficacy of each processing technique.
Readers will learn about the variety, characteristics, advantages, challenges and optimum parameters for each process, hence further enabling the targeted selection of coatings and technologies used to enhance long-term implant-bone integration.
- Reviews the fundamental theories and challenges of biomaterials biocompatibility, including standards and regulations
- Provides an overview of the cellular and molecular mechanisms involved in host responses to biomaterials
- Systematically looks at cellular response and tissue response for a wide range of biomaterials, including polymers, metals, ceramics, alloys and nanomaterials
1. General Concepts of Osseoconductive Surface Engineering 2. Plasma Spraying Process for Osseoconductive Surface Engineering 3. Vapor Deposition Process for Osseoconductive Surface Engineering 4. Plasma Electrolyte Oxidation Process for Osseoconductive Surface Engineering 5. Biomimetic Coating Process for Osseoconductive Surface Engineering 6. Porous Structuring Process for Osseoconductive Surface Engineering 7. Effectiveness of Osseoconductive surface engineering Methods & Future Perspective Glossaries
Mr. Amirhossein Goharian is an independent product developer in the field of orthopedic implants. He holds a master's degree in both biomechanical and biomaterial engineering. With background in mechanics, biomaterials, and biomechanics, he has been engaged in research and development in the areas of trauma implants and total joint replacements since 2011. His main concern and interest in the development of orthopedic implants is the effective incorporation of biomechanical, material, biological, and clinical facets simultaneously to optimize the implant design, technology, and features and ultimately to enhance the biomechanical and clinical benefits of orthopedic implants in treatment of bone injuries, particularly in patients with osteoporotic bones. He attempts to challenge current concepts and methods of evaluation and development of orthopedic implants and to create and propose novel concepts for future development of these products. In the area of trauma plating systems, he has acquired rigorous and significant information regarding (1) design engineering, (2) biomechanical testing and analysis, (3) clinical studies and investigations, and (4) bone biology, bone biomechanics, and muscle-tendons constraints on effectiveness of trauma plating fixation in treatment of bone fractures. His experience and studies with regard to trauma plating systems motivated the writing of this reference book on this topic. As was presented in this publication, he aims to explore new development concepts and novel conceptual implants in future publications with the hope of advancing the biomechanical and clinical benefits of orthopedic implants.