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Lignin-based Materials for Biomedical Applications. Preparation, Characterization, and Implementation

  • ID: 5180515
  • Book
  • July 2021
  • Elsevier Science and Technology

Lignin-based Materials for Biomedical Applications: Preparation, Characterization, and Implementation explores the emerging area of lignin-based materials as a platform for advanced biomedical applications, guiding the reader from source through to implementation.

The first part of the book introduces the basics of lignin, including extraction methods, chemical modifications, structure and composition, and properties that make lignin suitable for biomedical applications. In addition, structural characterization techniques are described in detail. The next chapters focus on the preparation of lignin-based materials for biomedical applications, presenting methodologies for lignin-based nanoparticles, hydrogels, aerogels, and nanofibers, and providing in-depth coverage of lignin-based materials with specific properties-including antioxidant properties, UV absorbing capability, antimicrobial properties, and colloidal particles with tailored properties-and applications, such as drug and gene delivery, and tissue engineering. Finally, future perspectives and possible new applications are considered.

This is an essential reference for all those with an interest in lignin-based materials and their biomedical applications, including researchers and advanced students across bio-based polymers, polymer science, polymer chemistry, biomaterials, nanotechnology, materials science and engineering, drug delivery, and biomedical engineering, as well as industrial R&D and scientists involved with bio-based polymers, specifically for biomedical applications.

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1 Introduction to lignocellulosic materials 2 Lignin: an innovative, complex, and highly flexible plant material/component 3 Lignin extraction and isolation methods 4 Types of lignin, properties, and structural characterization techniques 5 Chemical modifications of lignin 6 Requirements and properties of biomaterials for biomedical applications 7 Development of lignin-based nanoparticles: fabrication methods and functionalization approaches 8 Lignin-based materials with UV-blocking property 9 Lignin-based materials with antioxidant and antimicrobial properties 10 Lignin-based materials for drug and gene delivery 11 Fabrication of lignin-based hydrogels and their applications 12 Present and future prospective of lignin-based materials in biomedical fields

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Patrícia Figueiredo Division of Pharmaceutical Chemistry and Technology, University of Helsinki, Finland. Patrícia Figueiredo is a postdoctoral researcher at the University of Helsinki, where she obtained her PhD in Pharmaceutical Technology with honors in 2020. Her research is focused on the development of lignin-based nanosystems with potential application in biomedicine and food science. She has authored/co-authored 37 publications, including reviews and book chapters, and 6 oral/poster presentations in international scientific meetings. She also has more than 800 citations and h-index=14. Hélder A. Santos Drug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland; Helsinki Institute of Life Science (HiLIFE), University of Helsinki, Helsinki, Finland; Department of Biomedical Engineering, University Medical Center Groningen/University of Groningen, Groningen, The Netherlands. Hélder A. Santos is a Full Professor in Pharmaceutical Nanotechnology at the Faculty of Pharmacy of the University of Helsinki (Finland), Head of the Nanomedicines and Biomedical Engineering Lab, Director of the Doctoral Program in Drug Research, Director of FinPharmaNet in Finland, Chair of the Controlled Release Society Focus Group in Nanomedicine and Nanoscale Delivery, and Chairman and co-founder of Capsamedix Oy. Prof. Santos' research is focused on nanobiomaterials, including nanoporous silica/silicon materials and polymeric-based nanoparticles for controlled drug delivery, diagnostics, and therapy. His research interests include the development of nanoparticles/nanomedicines for biomedical and healthcare applications. His current work builds a bridge between engineering, pharmaceutical, and medical research. He is the author/co-author of more than 330 publications, including reviews, journal editorials, book chapters, 4 edited books, and more than 260 conference proceedings/abstracts. He also holds 4 patents in the field.
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