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Liquid Biopsy Markets by Cancer Type and by Usage Type with Impact of COVID-19 Pandemic. Including Executive and Consultant Guides and Customized Forecasting and Analysis 2021-2025

  • ID: 5189748
  • Report
  • November 2020
  • Region: Global
  • 396 Pages
  • Howe Sound Research
Liquid Biopsy Progress Delayed by COVID Pandemic but Huge Cancer Screening Opportunity Still Looms

FEATURED COMPANIES

  • Abbott Diagnostics
  • Bioarray Genetics
  • Circulogene
  • Freenome
  • Janssen Diagnostics
  • Promega
  • MORE

The Screening, Diagnostic, Therapy Selection, Recurrence Monitoring and Screening Market Potential are all explored in this report. What is the impact of the COVID pandemic on the Liquid Biopsy market? This report provides a detailed analysis.

Circulating Tumor Cells? Cell-Free DNA? Exosomes? Find out about the technology in readily understood terms that explain the jargon. Find the opportunities and pitfalls. Understand growth expectations and the ultimate potential market size.

A revolution in cancer diagnostics is occurring using in vitro blood testing to identify cancer DNA. The technology has created the possibility of widespread screening for all types of cancers with a blood test.

GRAIL, a new company with impressive backing, has announced a single blood test to detect all cancers. The company is now working on a 10,000-plus subject study, called the Circulating Cell-Free Genome Atlas (CCGA) to help identify cancer early. The technology is moving faster than the market. New technology that definitively identifies disease conditions from blood samples is poised to replace expensive invasive surgical biopsy procedures. The market is still in its infancy but has just moved out of the development phase and into the growth phase. The impact on the health care industry is enormous. The report forecasts the market size out to 2024. In addition, the report looks at potential market sizes by country, by cancer and by the four types of usage: screening, diagnosis, therapy selection and recurrence monitoring.

The report includes detailed breakouts for 15 Countries and 4 Regions along with breakouts for Lung, Breast, Colorectal, Prostate, Cervical, and Other Cancers as well as breakouts by Screening/Early Detection, Diagnostic, Therapy Monitoring and Recurrence Monitoring.

Note: Product cover images may vary from those shown

FEATURED COMPANIES

  • Abbott Diagnostics
  • Bioarray Genetics
  • Circulogene
  • Freenome
  • Janssen Diagnostics
  • Promega
  • MORE

Liquid Biopsy Market - Strategic Situation Analysis & Impact of COVID-19

  • Guide for Executives, Marketing, Sales and Business Development Staff
  • Guide for Management Consultants and Investment Advisors

1. Introduction and Market Definition
1.1 What is Liquid Biopsy?
1.2 The Sequencing Revolution
1.3 Market Definition
1.3.1 Revenue Market Size
1.4 Methodology
1.4.1 Authors
1.4.2 Sources
1.5 A Spending Perspective on Liquid Biopsy
1.5.1 An Historical Look at Clinical Testing

2. Market Overview
2.1 Players in a Dynamic Market
2.1.1 Academic Research Lab
2.1.2 Diagnostic Test Developer
2.1.3 Genomic Instrumentation Supplier
2.1.3.1 Cell Separation and Viewing Instrumentation Supplier
2.1.4 Pharmaceutical/Reagent Supplier
2.1.5 Independent Testing Lab
2.1.6 Public National/regional lab
2.1.7 Hospital lab
2.1.8 Physician Lab
2.1.9 Audit Body
2.1.10 Certification Body
2.2 Using Biopsies
2.2.1 Cancer
2.2.2 Precancerous conditions
2.2.3 Inflammatory conditions
2.3 Biopsy Sites
2.4 The Situation Today - Biopsy Analysis
2.5 Evidence of Cancer - Liquid Biopsy Technology
2.5.1 The Big Picture on Liquid Biopsy Technology
2.5.2 The Role of CTCs
2.5.2.1 Types of CTCs
2.5.2.2 CellSearch Detection- Ultimate Sensitivity
2.5.2.3 Epic Sciences Detection- Imaging Takes the Lead
2.5.2.4 Maintrac Detection - The Microscope
2.5.2.5 Other Methods
2.5.3 ctDNA - Going Mainstream?
2.5.4 Exosomes and Micro Vesicles - New Kid on the Block
2.5.5 The Multiple Play
2.6 Cancer Treatment Protocol Under Siege
2.6.1 Issues to Liquid Biopsy Adoption - Double Diagnostics
2.6.2 The Cancer Screening Market Opportunity
2.6.2.1 GRAIL - What Is It?
2.6.3 Cancer Management vs. Diagnosis
2.6.3.1 The Role of Risk Assessment
2.6.3.2 Managing Therapy
2.6.3.3 Monitoring Disease - What Is It?
2.6.4 Phases of Adoption - Looking into The Future
2.6.5 The Promise of Liquid Biopsy
2.7 Structure of Industry Plays a Part
2.7.1 Hospital Testing Share
2.7.2 Economies of Scale
2.7.2.1 Hospital vs. Central Lab
2.7.3 Physician Office Lab’s
2.7.4 Physician’s and POCT

3. Market Trends
3.1 Factors Driving Growth
3.1.1 Non Invasive Game Changer
3.1.2 Lower Cost
3.1.3 Greater Accuracy
3.1.4 Wide Range of Potential Uses
3.1.5 Aging Population
3.2 Factors Limiting Growth
3.2.1 Lower prices
3.2.2 Lack of Standards
3.2.3 Protocol Resistance
3.2.4 Initial Adoption Cost
3.2.5 COVID-19
3.3 Instrumentation and Automation
3.3.1 Instruments Key to Market Share
3.3.2 Bioinformatics Plays a Role
3.4 Diagnostic Technology Development
3.4.1 Next Generation Sequencing Fuels a Revolution
3.4.2 Impact of NGS on pricing
3.4.3 Pharmacogenomics Blurs Diagnosis and Treatment
3.4.4 CGES Testing, A Brave New World
3.4.5 Biochips/Giant magnetoresistance based assay

4. Liquid Biopsy Recent Developments
4.1 Recent Developments - Importance and How to Use This Section
4.1.1 Importance of These Developments
4.1.2 How to Use This Section

  • Liquid Biopsy NGS Panels - Diverse Test Claims
  • CMS Colon Cancer Screening Memo Bodes Well for Assays
  • Natera Liquid Biopsy Test Coverage to Expand
  • Freenome Closes Financing to Support Early Cancer Detection Trial
  • C$2.6M Liquid Biopsy Initiative
  • NeoGenomics, Inivata Partner for Lung Cancer Liquid Biopsy
  • Liquid Biopsy Shows Promise as Screen for Cancers
  • Inivata launches RaDaR™ for the detection of residual disease and recurrence
  • Liquid Biopsy Assay Detects 50+ Types of Cancer
  • Liquid Biopsy Study Confirms Concordance with Tissue Biopsy
  • Guardant Health Liquid Biopsy Expands Medicare Coverage
  • Aethlon Medical Lands Grant for Exosome Isolation Device
  • Biolidics to Develop Liquid Biopsy Breast Cancer Test
  • Liquid Biopsy Equal to Tissue to Indicate Immunotherapy Response
  • Exact Sciences buys Genomic Health
  • Multi-Gene Liquid Biopsy Breast Cancer Panel
  • Bio-Techne receives FDA breakthrough device for prostate cancer liquid biopsy
  • Thrive to Develop Earlier Detection of Multiple Cancer Types
  • Guardant Health Liquid Biopsy Test to be Covered by EviCore
  • Liquid biopsy combines Illumina’s ‘ultradeep’ sequencing with Grail’s machine learning
  • Biocept Partnership Offering for Liquid Biopsy Adds Several Key Services
  • Natera Commercializes Tumor Whole Exome Sequencing from Plasma
  • Sienna Buys Liquid Biopsy & Exosome Isolation Technology
  • Inivata Completes £39.8M Series B Funding Round
  • Bio-Rad Clinical ddPCR Test, Diagnostic System Get FDA Clearance
  • CellMax, Medigen Biotech Partner in Colorectal Cancer Clinical Trials
  • Biodesix Acquires Integrated Diagnostics
  • Predicine, Kintor Pharmaceuticals Partner on Clinical Trials, CDx
  • Bio-Techne to Acquire Exosome Dx for Up to $575M
  • GRAIL Announces Data on Detection of Early-Stage Lung Cancers
  • Precision for Medicine Acquires ApoCell
  • NeoGenomics to Acquire Genoptix for Cash, Stocks
  • PGDx Liquid Biopsy Assay to be Used in Cancer Drug Study
  • Liquid Biopsy IDs More NSCLC Mutations in Study of Guardant Test
  • Inivata Gets Draft Medicare Coverage Determination for Lung Cancer Test

5. Profiles of Key Players

  • Abbott Diagnostics
  • AccuraGen Inc
  • Acuamark Diagnostics
  • Admera Health, LLC
  • Agena Bioscience, Inc
  • Agilent
  • Amoy Diagnostics Co., Ltd
  • Anchor Dx
  • ANGLE plc
  • ApoCell, Inc
  • ArcherDx, Inc
  • Asuragen
  • AVIVA Biosciences
  • Baylor Miraca Genetics Laboratories
  • Beckman Coulter, Inc.
  • Becton, Dickinson and Company
  • BGI Genomics Co. Ltd
  • Bioarray Genetics
  • Biocartis
  • Biocept, Inc
  • Biodesix Inc
  • BioFluidica
  • bioMérieux Diagnostics
  • Bioneer Corporation
  • Bio-Rad Laboratories, Inc
  • Bio-Techne
  • Bioview
  • Bolidics
  • Boreal Genomics
  • Caris Molecular Diagnostics
  • CellMax Life
  • Cepheid (now Danaher)
  • Chronix Biomedical
  • Circulogene
  • Clinical Genomics
  • Cynvenio
  • Cytolumina Technologies Corp
  • CytoTrack
  • Datar Cancer Genetics Limited
  • Diagenode Diagnostics
  • Diagnologix LLC
  • Enzo Life Sciences, Inc
  • Epic Sciences
  • Epigenomics AG
  • Eurofins Scientific
  • Exosome Diagnostics
  • Exosome Sciences
  • Fluidigm Corp
  • Fluxion Biosciences
  • Foundation Medicine
  • Freenome
  • GeneFirst Ltd.
  • Genetron Health (Beijing) Co., Ltd
  • Genomic Health
  • GILUPI Nanomedizin
  • Grail, Inc
  • Guardant Health
  • HansaBiomed
  • HeiScreen
  • Helomics
  • Horizon Discovery
  • iCellate
  • Illumina
  • Incell Dx
  • Inivata
  • Integrated Diagnostics
  • Janssen Diagnostics
  • MDNA Life SCIENCES, Inc
  • MDx Health
  • Menarini Silicon Biosystems
  • Millipore Sigma
  • Miltenyi Biotec
  • miR Scientific
  • Molecular MD
  • Myriad Genetics/Myriad RBM
  • NantHealth, Inc
  • Natera
  • NeoGenomics
  • New Oncology
  • Novogene Bioinformatics Technology Co., Ltd
  • Oncocyte
  • OncoDNA
  • Oxford Nanopore Technologies
  • Perkin Elmer
  • Personal Genome Diagnostics
  • PrecisionMed
  • Promega
  • Qiagen Gmbh
  • Quidel
  • Rarecells SAS
  • RareCyte
  • Resolution Biosciences, Inc
  • Roche Molecular Diagnostics
  • Screencell
  • Siemens Healthineers
  • simfo GmbH
  • Singlera Genomics Inc
  • SRI International
  • Sysmex Inostics
  • Tempus Labs, Inc
  • Thermo Fisher Scientific Inc
  • Thrive Earlier Detection
  • Trovagene
  • Volition

6. The Global Market for Liquid Biopsy Diagnostics
6.1 Global Market Overview by Country
6.1.1 Table - Global Market by Country
6.1.2 Chart - Global Market by Country
6.2 Global Market by Cancer - Overview
6.2.1 Table - Global Market by Cancer
6.2.2 Chart - Global Market by Cancer - Base/Final Year Comparison
6.2.3 Chart - Global Market by Cancer - Base Year
6.2.4 Chart - Global Market by Cancer - End Year
6.2.5 Chart - Global Market by Cancer - Share by Year
6.2.6 Chart - Global Market by Cancer - Segments Growth
6.3 Global Market by Usage - Overview
6.3.1 Table - Global Market by Usage
6.3.2 Chart - Global Market by Usage - Base/Final Year Comparison
6.3.3 Chart - Global Market by Usage - Base Year
6.3.4 Chart - Global Market by Usage - End Year
6.3.5 Chart - Global Market by Usage - Share by Year
6.3.6 Chart - Global Market by Usage - Segments Growth

7. Global Liquid Biopsy Diagnostic Markets - By Cancer
7.1 Breast
7.1.1 Table Breast - by Country
7.1.2 Chart - Breast Growth
7.2 Colorectal
7.2.1 Table Colorectal - by Country
7.2.2 Chart - Colorectal Growth
7.3 Cervical
7.3.1 Table Cervical - by Country
7.3.2 Chart - Cervical Growth
7.4 Lung
7.4.1 Table Lung - by Country
7.4.2 Chart - Lung Growth
7.5 Prostate
7.5.1 Table Prostate - by Country
7.5.2 Chart - Prostate Growth
7.6 Other
7.6.1 Table Other - by Country
7.6.2 Chart - Other Growth

8. Global Liquid Biopsy Diagnostic Markets - by Usage
8.1 Screening
8.1.1 Table Screening - by Country
8.1.2 Chart - Screening Growth
8.2 Diagnostic
8.2.1 Table Diagnostic - by Country
8.2.2 Chart - Diagnostic Growth
8.3 Therapy
8.3.1 Table Therapy - by Country
8.3.2 Chart - Therapy Growth
8.4 Monitor
8.4.1 Table Monitor - by Country
8.4.2 Chart - Monitor Growth

Appendices

  • United States Medicare System: 2020 Clinical Laboratory Fees Schedule
  • COVID-19 Approved Assays

List of Tables
Table 1 Medicare Clinical Lab Expenditures Actual & Forecast 2014 to 2024 ($Billion)
Table 2 Market Players by Type
Table 3 Biopsy Sites
Table 4 Advantages of Liquid Biopsy in Screening Market
Table 5 Outlook - Phases of Liquid Biopsy Adoption by Year
Table 6 Five Factors Driving Growth
Table 7 Factors Limiting Growth
Table 8 Key Diagnostic Laboratory Technology Trends
Table 9 Next Generation Sequencing Technologies - Speed and Cost
Table 10 - Global Market by Region
Table 11 Global Market by Cancer
Table 12 Global Market by Usage
Table 13 Breast by Country
Table 14 Colorectal by Country
Table 15 Cervical by Country
Table 16 Lung by Country
Table 17 Prostate by Country
Table 18 Other by Country
Table 19 Screening by Country
Table 20 Diagnostic by Country
Table 21 Therapy by Country
Table 22 Monitor by Country
Table 23 2020 Clinical Lab Fee Schedule
Table 24 COVID -19 Approved Assays

List of Figures
Figure 1 Medicare Clinical Lab Expenditures 2014 to 2024 ($Million)
Figure 2 Comparison of Liquid Biopsy Classes
Figure 3 Characteristics of Different Vesicle Types
Figure 4 Percentage of World Population Over 65
Figure 5 Global Market Density Chart
Figure 6 Global Market by Cancer - Base vs. Final
Figure 7 Global Market by Cancer Base Year
Figure 8 Global Market by Cancer End Year
Figure 9 Cancer Share by Year
Figure 10 Cancer Segments Growth
Figure 11 Global Market by Usage - Base vs. Final
Figure 12 Global Market by Usage Base Year
Figure 13 Global Market by Usage End Year
Figure 14 Usage Share by Year
Figure 15 Usage Segments Growth
Figure 16 Breast Growth
Figure 17 Colorectal Diagnostics Growth
Figure 18 Cervical Growth
Figure 19 Lung Growth
Figure 20 Prostate Growth
Figure 21 Other Growth
Figure 22 Screening Growth
Figure 23 Diagnostic Growth
Figure 24 Therapy Growth
Figure 25 Monitor Growth

Note: Product cover images may vary from those shown

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  • Abbott Diagnostics
  • AccuraGen Inc
  • Acuamark Diagnostics
  • Admera Health, LLC
  • Agena Bioscience, Inc
  • Agilent
  • Amoy Diagnostics Co., Ltd
  • Anchor Dx
  • ANGLE plc
  • ApoCell, Inc
  • ArcherDx, Inc
  • Asuragen
  • AVIVA Biosciences
  • Baylor Miraca Genetics Laboratories
  • Beckman Coulter, Inc.
  • Becton, Dickinson and Company
  • BGI Genomics Co. Ltd
  • Bioarray Genetics
  • Biocartis
  • Biocept, Inc
  • Biodesix Inc
  • BioFluidica
  • bioMérieux Diagnostics
  • Bioneer Corporation
  • Bio-Rad Laboratories, Inc
  • Bio-Techne
  • Bioview
  • Bolidics
  • Boreal Genomics
  • Caris Molecular Diagnostics
  • CellMax Life
  • Cepheid (now Danaher)
  • Chronix Biomedical
  • Circulogene
  • Clinical Genomics
  • Cynvenio
  • Cytolumina Technologies Corp
  • CytoTrack
  • Datar Cancer Genetics Limited
  • Diagenode Diagnostics
  • Diagnologix LLC
  • Enzo Life Sciences, Inc
  • Epic Sciences
  • Epigenomics AG
  • Eurofins Scientific
  • Exosome Diagnostics
  • Exosome Sciences
  • Fluidigm Corp
  • Fluxion Biosciences
  • Foundation Medicine
  • Freenome
  • GeneFirst Ltd.
  • Genetron Health (Beijing) Co., Ltd
  • Genomic Health
  • GILUPI Nanomedizin
  • Grail, Inc
  • Guardant Health
  • HansaBiomed
  • HeiScreen
  • Helomics
  • Horizon Discovery
  • iCellate
  • Illumina
  • Incell Dx
  • Inivata
  • Integrated Diagnostics
  • Janssen Diagnostics
  • MDNA Life SCIENCES, Inc
  • MDx Health
  • Menarini Silicon Biosystems
  • Millipore Sigma
  • Miltenyi Biotec
  • miR Scientific
  • Molecular MD
  • Myriad Genetics/Myriad RBM
  • NantHealth, Inc
  • Natera
  • NeoGenomics
  • New Oncology
  • Novogene Bioinformatics Technology Co., Ltd
  • Oncocyte
  • OncoDNA
  • Oxford Nanopore Technologies
  • Perkin Elmer
  • Personal Genome Diagnostics
  • PrecisionMed
  • Promega
  • Qiagen Gmbh
  • Quidel
  • Rarecells SAS
  • RareCyte
  • Resolution Biosciences, Inc
  • Roche Molecular Diagnostics
  • Screencell
  • Siemens Healthineers
  • simfo GmbH
  • Singlera Genomics Inc
  • SRI International
  • Sysmex Inostics
  • Tempus Labs, Inc
  • Thermo Fisher Scientific Inc
  • Thrive Earlier Detection
  • Trovagene
  • Volition
Note: Product cover images may vary from those shown
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