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2021 Clinical Trial Analytics of the Microbiome Landscape

  • Report

  • 9 Pages
  • April 2021
  • Region: Global
  • Arogyam
  • ID: 5407317

The number of ongoing clinical trials with a focus on the microbiome has risen substantially from 2015-2019 to 190 trials, with almost seven times the number of trials recorded in 2019 relative to 2015. Like in clinical trials in other spaces, COVID-19 has impacted the number of ongoing clinical trials in 2020. Thankfully, the majority of these can be expected to re-initiate in 2021. 2020 also saw three key clinical trial successes that have spurred the industry, namely that of Seres, Rebiotix, and Finch. All three companies target recurrent C. diff infections, Seres announced that it has met its primary end point in a phase 3 trial, while Rebiotix/Ferring announces positive preliminary phase 3 data, and Finch release phase 2 data that showed statistically significant benefit. These breakthroughs are likely to pave the way for other indications. However, regulatory uncertainties regarding classification and frameworks for microbiome therapeutics continue to remain a barrier.


Table of Contents

  • Introduction: Report Scope and Methodology
  • Microbiome Based Clinical Trial Analytics (2015-2020)
    • Ongoing trials trend
    • Distribution by region and countries
    • Distribution by phase and sponsor type
    • Top 10 sponsors and top 10 companies with most ongoing microbiome trials
    • Distributions by top 10 therapy areas and indications
    • Distributions by endpoint classification, molecule type, and interventions

  • About the Analyst

Samples

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Companies Mentioned

  • Shanghai Institute of Hematology
  • Shanghai Rui Jin Hospital
  • Edith Cowan University
  • Academic Medical Center
  • Big Ten Cancer Research Consortium
  • DNA Chip Research Inc
  • The Royal Marsden NHS Foundation Trust
  • University of Amsterdam
  • University of Pittsburgh
  • University of Wisconsin Hospitals and Clinics Authority
  • Vedanta Biosciences Inc
  • Enterome Bioscience SA
  • Medical College of Wisconsin
  • Fred Hutchinson/University of Washington Cancer Consortium
  • Genome & Co
  • National Cancer Institute US
  • UNC Lineberger Comprehensive Cancer Center
  • University of Texas MD Anderson Cancer Center
  • University of Washington
  • City of Hope
  • MaaT Pharma
  • Vaximm AG
  • 4D Pharma Plc
  • Institut fur Frauengesundheit GmbH
  • Karolinska University Hospital
  • Lawson Health Research Institute
  • Mayo Clinic
  • Medica Scientia Innovation Research SL
  • Morinaga Milk Industry Co Ltd
  • NYU Langone Health System
  • Perlmutter Cancer Center
  • Puma Biotechnology Inc
  • Sun Yat-sen University
  • The First Affiliated Hospital of Harbin Medical University
  • University Health Network
  • University of Kansas Cancer Center
  • University of Kansas Medical Center
  • Fred Hutchinson Cancer Research Center
  • University of California San Francisco
  • Baptist Health South Florida Inc
  • Ghent University Hospital
  • Saarland University Hospital
  • Asan Medical Center
  • Dana-Farber/Harvard Cancer Center
  • Massachusetts General Hospital
  • The Affiliated Hospital of Inner Mongolia Medical University
  • University Hospital of Careggi
  • Zealand University Hospital
  • Chonnam National University Hwasun Hospital
  • Maastricht University Medical Center
  • Hackensack University Medical Center
  • Haemato Oncology Foundation for Adults in the Netherlands
  • University Medical Center Groningen
  • University of Chicago
  • University of Chicago Comprehensive Cancer Center
  • Roswell Park Cancer Institute
  • AIO Studien GmbH
  • Rigshospitalet
  • Dana-Farber Cancer Institute Inc
  • Johns Hopkins University
  • Sidney Kimmel Comprehensive Cancer Center
  • Mercy Medical Center Inc
  • Institut Catala d'Oncologia
  • National University Hospital
  • Providence Health &
  • Services
  • University Hospital Freiburg
  • University of Arkansas
  • Canadian Cancer Trials Group
  • Cancer Research Institute
  • Centre Leon Berard
  • European Organization for Research and Treatment of Cancer
  • Queen''s University
  • UPMC Hillman Cancer Center
  • University of California Davis
  • Fox Chase Cancer Center
  • University of Wisconsin Madison
  • Wake Forest University Health Sciences
  • Aarhus University Hospital
  • Cambridge University Hospitals NHS Foundation Trust
  • Ontario Clinical Oncology Group
  • Lung Cancer Group Cologne
  • University of Cologne
  • Bristol-Myers Squibb Co
  • Dynavax Technologies Corp
  • Synlogic Inc
  • University of Leicester
  • Antoni van Leeuwenhoek
  • Ardigen SA
  • Australia and New Zealand Melanoma Trials Group
  • East and North Hertfordshire NHS Trust
  • Parker Institute for Cancer Immunotherapy
  • Peter MacCallum Cancer Centre
  • Sheba Medical Center
  • Medical University of South Carolina
  • European Thoracic Oncology Platform
  • Hospital Israelita Albert Einstein
  • Indiana University Melvin and Bren Simon Cancer Center
  • Kansai Clinical Oncology Group
  • Merck & Co Inc
  • NewYork-Presbyterian Hospital
  • Oslo University Hospital
  • Shanghai Pulmonary Hospital
  • Weill Cornell Medical College
  • Memorial Sloan Kettering Cancer Center
  • H. Lee Moffitt Cancer Center & Research Institute Inc
  • University of Colorado Denver
  • Columbia University
  • Herbert Irving Comprehensive Cancer Center
  • Showa University
  • Showa University School of Medicine
  • AstraZeneca Plc
  • The Netherlands Cancer Institute
  • Melanoma Institute Australia
  • West China Hospital of Sichuan University
  • BiomX Inc
  • McMaster University
  • University of Queensland
  • Uniformed Services University of the Health Sciences
  • Scientific Research Institute of Physical-Chemical Medicine
  • University of Texas Health Science Center at Houston
  • Catholic University of Louvain
  • Saint Luc University Hospital
  • Oxford University Clinical Research Unit
  • Yonsei University
  • 9 Meters Biopharma Inc
  • The University of Adelaide
  • Institute of Biomedical Research August Pi i Sunyer
  • Philadelphia VA Medical Center
  • Children's Hospital of Philadelphia
  • Deinove SAS
  • Duke University
  • Washington University School of Medicine
  • Min-Sheng General Hospital
  • McMaster Children's Hospital
  • Boston Children''s Hospital
  • Alpinia Laudanum Institute of Phytopharmaceutical Sciences AG
  • Arizona State University
  • Enterin Inc
  • Fooyin University
  • LKH University Hospital Graz
  • Medical University of Graz
  • Wuxi Third People's Hospital
  • Aichi Medical University
  • Children''s Hospital of Philadelphia
  • First Affiliated Hospital of Kunming Medical College
  • Fujita Health University School of Medicine
  • Guy's and St Thomas' NHS Foundation Trust
  • Hyogo College of Medicine
  • Immunic Inc
  • Jichi Medical University
  • Kanazawa University
  • King's College London
  • Qu Biologics Inc
  • Schneider Children's Medical Center of Israel
  • Shiga University of Medical Science
  • Takeda Pharmaceutical Co Ltd
  • Cedars-Sinai Medical Center
  • Glock Health, Science and Research GmbH
  • International Centre for Diarrhoeal Disease Research Bangladesh
  • North Zealand Hospital
  • Singapore General Hospital
  • University of Ulm
  • Xiyuan Hospital of China Academy of Chinese Medical Sciences
  • Targid University Leuven
  • Queen Fabiola Children's University Hospital
  • Shanghai General Hospital
  • Shanghai Jiao Tong University School of Medicine
  • Zhejiang University School of Medicine Hospital 1
  • Leading BioSciences Inc
  • Swansea Bay University Health Board
  • National University of Natural Medicine
  • Tel Aviv Sourasky Medical Center
  • The Chinese University of Hong Kong
  • People's Hospital of Tibet Autonomous Region
  • Shanghai 10th People's Hospital
  • Copenhagen University Hospital Hvidovre
  • Fundacio Institut de Recerca de l''Hospital de la Santa Creu i Sant Pau
  • Intercept Pharmaceuticals Inc
  • The Peking University School of Stomatology
  • Chuncheon Sacred Heart Hospital
  • Leiden University Medical Center
  • Translational Research Institute for Metabolism and Diabetes
  • The First Affiliated Hospital of Chengdu Medical College
  • Amsterdam University Medical Center
  • Applied Molecular Transport Inc
  • ISOThrive Inc
  • Assaf Harofeh Medical Center
  • Assembly Biosciences Inc
  • Baptist Memorial Health Care Corp
  • Children's Hospital Los Angeles
  • Kaleido Biosciences Inc
  • Nubiyota LLC
  • University of Birmingham
  • University of Vermont
  • Wolfson Medical Center
  • Chengdu University of Traditional Chinese Medicine Hospital
  • Evolve Biosystems Inc
  • Functional Gut Clinic Ltd
  • Institute Allergosan
  • Plymouth Hospitals NHS Trust
  • Rutgers The State University of New Jersey
  • Southern Cross University
  • University College Cork
  • University Hospital Schleswig-Holstein
  • University of Calgary
  • University of California San Diego
  • University of Pennsylvania
  • Seres Therapeutics Inc
  • University Hospitals Leuven
  • Albert Einstein College of Medicine
  • College of Medicine University of Malawi
  • CIncinnati Children's Hospital Medical Center
  • Hellenic Institute for the Study of Sepsis
  • Hospices Civils de Lyon
  • Lallemand Health Solutions
  • Murdoch Childrens Research Institute
  • Rotterdam Foundation Research Consortium Pediatrics
  • Sint Franciscus Gasthuis
  • VU University Medical Center
  • University of Oxford
  • Hadassah Medical Center
  • London School of Hygiene &
  • Tropical Medicine
  • AO Foundation
  • NHS Tayside
  • University of Dundee
  • Francis I. Proctor Foundation
  • University of Maryland Baltimore
  • Acurx Pharmaceuticals LLC
  • Finch Therapeutics Group
  • Rebiotix Inc
  • University of North Carolina at Chapel Hill
  • Clinical Directors Network Inc
  • Winclove Probiotics BV
  • AB-Biotics SA
  • F. Hoffmann-La Roche Ltd
  • The National Institute of Allergy and Infectious Diseases
  • Uconn Health
  • UKSH Campus Kiel
  • Rambam Health Care Campus
  • Assistance Publique - Hopitaux de Paris
  • Children’s Hospital of Fudan University
  • Jiangnan University
  • Kobe University
  • Peoples Hospital of Tinghu District of Yancheng City
  • Servatus Ltd
  • Napo Pharmaceuticals Inc
  • British Columbia Centre for Disease Control
  • Clinical and Translational Science Institute
  • Fundacio Clinic per a la Recerca Biomedica
  • Hospital Clinic of Barcelona
  • IRCCS San Raffaele Hospital
  • National Institute of Child Health and Human Development
  • National Institute of Mental Health
  • The HIV Vaccine Trials Network
  • University of Minnesota
  • University of the Witwatersrand
  • University of Toronto
  • Jenner Institute
  • Bandim Health Project
  • London School of Hygiene & Tropical Medicine
  • Rothman Orthopaedic Institute
  • Institute of Tropical Medicine
  • Jinan University
  • Stellenbosch University
  • Emory University
  • The University of British Columbia
  • Aristotle University of Thessaloniki
  • The Fertility Clinic Skive Regional Hospital
  • Ann &
  • Robert H Lurie Children’s Hospital of Chicago
  • UAS LifeSciences LLC
  • Women's and Children's Health Network
  • Kanazawa University Graduate School of Medical Sciences
  • Taipei Medical University Shuang Ho Hospital
  • Summit Therapeutics Plc
  • Baylor College of Medicine
  • Parc de Salut Mar
  • Zhejiang University School of Medicine Hospital 2
  • Zunyi Medical University
  • Azienda Ospedaliero-Universitaria di Modena
  • Nottingham University Hospitals NHS Trust
  • Clinic for Psychiatry and Psychotherapy
  • University of Surrey
  • European Commission
  • Oregon Health &
  • Science University
  • Vall d’Hebron Barcelona Hospital Campus
  • Kubota Children's Clinic
  • Peking Union Medical College Hospital
  • University of Rome Tor Vergata
  • Andalusian Public Foundation for Research Management in Seville Health
  • FUDAN University
  • University of Texas Medical Branch at Galveston
  • University of Hong Kong
  • Nationwide Children''s Hospital
  • The Newcastle upon Tyne Hospitals NHS Foundation Trust
  • Monash University
  • Ohio University
  • Montefiore Medical Center
  • Beijing Chao-Yang Hospital
  • Central South University
  • King''s College London
  • China PLA General Hospital
  • Griffin Hospital
  • MedStar Health Research Institute
  • Alkahest Inc
  • Ghent University
  • Multidisciplinary Association for Psychedelic studies
  • Karnataka Institute of Medical Sciences
  • Rajiv Gandhi University of Health Sciences
  • Ohio State University Comprehensive Cancer Center
  • RWTH Aachen University
  • French Cardiology Society
  • South Western Sydney Local Health District
  • Steno Diabetes Center Copenhagen
  • George Washington University
  • AtoGen Co Ltd
  • Uppsala University
  • Nanjing Medical University
  • Sir Run Run Shaw Hospital
  • Poznan University of Life Sciences
  • Royal Perth Hospital
  • Aarhus University
  • Charles University
  • Guangdong Provincial Hospital of Traditional Chinese Medicine
  • Central South University Xiangya Hospital
  • Federico II University
  • Inland Norway University of Applied Sciences
  • RMIT University
  • Tokyo Metropolitan Tama Medical center
  • Garvan Institute of Medical Research
  • University of California
  • Indiana University
  • Southern Medical University Hospital 3
  • Aboca SpA
  • APP Latvian Biomedical Research and Study Centre
  • Life Science and Medical University Hospital 1
  • Nantong University Hospital 3
  • Royal Adelaide Hospital SA
  • University of Milan
  • Bionou Research, S.L.
  • Centre for Human Drug Research
  • Integrative Skin Science and Research
  • University Hospital Antwerp
  • AOBiome LLC
  • Chang Gung Memorial Hospital
  • Gentofte University Hospital
  • Innovation and Development of Health Strategies
  • The Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine
  • Tehran University of Medical Sciences
  • University of Schleswig-Holstein
  • L'Oreal SA
  • Maruho Co Ltd
  • Erasmus MC
  • Reponex Pharmaceuticals Aps
  • Ilya Pharma AB
  • Alba Science Ltd
  • Micreos BV
  • Medical University of Vienna
  • The Sydney Children's Hospitals Network
  • Bispebjerg Hospital
  • Region Hovedstaden
  • University Hospital Tuebingen
  • The Massachusetts General Hospital Cancer Center
  • University of Erlangen-Nurnberg
  • High Institute for Education and Research in Transfusion Medicine
  • National Institute of Dental and Craniofacial Research
  • Stanford University
  • Quadram Institute Bioscience (UK)
  • Haga Teaching Hospital
  • Juliana Children's Hospital
  • University Medical Center Utrecht
  • Counties Manukau District Health Board
  • Harefield NHS Foundation Trust
  • Health Research Council of New Zealand
  • Royal Brompton &
  • Shanghai University of Traditional Chinese Medicine
  • Seattle Children''s Hospital
  • Vertex Pharmaceuticals Inc
  • University Hospital Tubingen
  • Anhui Medical University
  • National Autonomous University of Mexico
  • Noos Srl
  • KoBioLabs Inc
  • Yakult Honsha Co Ltd
  • Charite University Hospital of Berlin
  • German Center for Cardiovascular Research (DZHK) EV
  • University of Alberta
  • Bio-Competence Centre of Healthy Dairy Products Llc
  • Charity University Medicine
  • Texas Tech University
  • Federal University of Sao Paulo
  • University of Alabama at Birmingham
  • University of Louisville
  • Innovation and Development of Strategies in Health
  • University College Dublin
  • Instituto Bernabeu
  • Region Skane
  • Buddhist Tzu Chi Medical Foundation
  • Springfield College
  • Taipei Tzu Chi Hospital
  • The National Institute of Diabetes and Digestive and Kidney Diseases
  • Tongji Hospital
  • U.S. National Institutes of Health
  • Maharishi Markandeshwar Institute of Medical Science and Research
  • University of Manitoba
  • Mohammed Bin Rashid University Of Medicine and Health Sciences
  • University Hospital Essen
  • Johnson & Johnson
  • Seoul St. Mary''s Hospital
  • Nestle SA
  • National Institute of Nutrition
  • Tufts University
  • Jinling Hospital
  • OpenBiome
  • Beijing Tongren Hospital
  • Capital Medical University
  • Toulouse University Hospital
  • Florida International University
  • Karolinska Institute
  • University of Campinas Brazil
  • Pennsylvania State University
  • Therapies Probionase Inc
  • Waikato Hospital
  • Texas Tech University Health Sciences Center
  • New York Medical College
  • Kaiser Permanente
  • University of Auckland
  • Aga Khan University
  • Cornell University
  • Helsinki University Central Hospital
  • Kyodo Milk Industry Co Ltd
  • Probiotical SpA
  • United States Army Research Institute of Environmental Medicine
  • University of Hohenheim
  • University of Texas Health Science Center at San Antonio
  • WCCT Global Inc
  • Zhejiang University
  • Fujicco Co Ltd
  • Jennewein Biotechnologie GmbH
  • Brigham and Women's Hospital
  • University of Oulu