The Intestine. Stem Cell Innovation in Health & Disease

Table of Contents

Section 1: Cutting edge research on the intestinal stem cell functions 1. Intestinal organoid cell culture as a new modality to intestinal function, cellular processes and stem cell functions 2. Intestinal organoids in gastrointestinal pathology

Section 2: Cutting edge research on stem cell application in the intestinal diseases (from bench to bed) 3. Intestinal organoid culture as a new test-bed for intestinal therapeutic research and development 4. Engineered stem cells combine stem cell and gene therapy approaches to move intestine therapy from bench to bed 5. Application of CRISPR/Cas9 and other gene editing/ engineering technology in intestine diseases 6. New approaches for intestine and colon repair via stem cell-based tissue engineering 7. iPSCs and intestine diseases from bench to bed 8. The potential of embryonic stem cells for treating intestinal diseases from bench to bed 9. Stem-cell therapy with bone marrow (hematopoietic) stem cells for intestinal diseases 10. Mesenchymal and other stem cell-therapy of intestinal diseases

Authors

Ahmed El-Hashash Associate Professor of Biomedicine, Texas A&M University, College Station, Texas, USA. Dr. El-Hashash is a fellow of the California Institute of Regenerative Medicine and New York University Medical School. Prof. El-Hashash worked as a senior biomedical research scientist at Mount Sinai School of Medicine of New York University and Children's Hospital Los Angeles. He was Assistant Professor and Principal Investigator of Stem Cell & Regenerative Medicine at Keck School of Medicine and Ostrow School of Dentistry of The University of Southern California. In 2016, Prof. El-Hashash joined The University of Edinburgh, Edinburgh Medical School-Zhejiang International Campus, as Tenure-Track Associate Professor and Senior Principal Investigator of Biomedicine, Stem Cell & Regenerative Medicine. Prof. El-Hashash has several breakthrough discoveries in genes/enzymes that control stem cell behavior and regenerative medicine and has published more than 25 papers in international journals and serves as an editorial board member of repute. He is the editor or author of several books on stem cell and regenerative medicine. Eiman Abdel Meguid Senior Lecturer, Centre for Biomedical Sciences Education, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, UK. She completed her PhD thesis at Eberhard-Karls Universit�t T�bingen, Germany. Dr Abdel Meguid is an innovative educator and researcher and has published multiple scientific works in leading journals and is a reviewer and a member of the editorial board of a number of journals. Dr Abdel Meguid taught gross anatomy to medical, dental, human biology students and students enrolled in MSc in clinical anatomy. Her research interests are in the areas of stem cells, lung development, anatomical pedagogy, teaching strategies, and the integration of novel technologies to enhance learning.